The Binding of Isaac: Rebirth Guide

Advice I wish someone told me when i was getting started in this game for The Binding of Isaac: Rebirth

Advice I wish someone told me when i was getting started in this game

Overview

I have played this game for a very long amount of time (mobile and pc) and ive been with it since the release of the orignal binding of isaac. here is the a collection of advice i wish someone would have told me. Some of it is opinion based. sorry if its just thrown together its still worth your time to read.PLEASE comment anything like this that you think i missed.

Characters to avoid playing early in the file

*don’t play judas or ??? for now that way when you get ankh or judas shadow and you havent already 100% with those characters then you can still get use out of those items.
*don’t play your least favorite characters for now (for me it’s lazarus and apollyon) , that way when you get edins blessing you can use it on those characters.
*last thing is i might not play isaac, eve, or the lost til you get there starting items because in my opinion that makes them exponentially better.

run objectives

instead of doing runs with the objective of going to dark room or chest shoot for boss rush or blue womb because the game continues after you hit those objectives and you can still hit dark room or chest

Devil room tips

In my opinion devil rooms/ devil room items are the most important thing in the game if you want a good run. Here are my tips to getting a devil room as much as possible.
*DEVIL ROOMS CANT OPEN ON THE FIRST FLOOR
*wait to pick up soul hearts and enter curse rooms until you are ready to leave the first floor
*When you pick up a joker card save it until your devilroom door doesnt open.
*100% the first floor to increase your chance to find soul hearts so you can get a devil room at the end of the second floor. EVEN WHEN SPEEDRUNNING (devil room chance on second floor is 100% if you take no readheart damage)
*when you havent taken red heart damage on a floor try to get to and fight a boss as fast as possible
*ALWAYS keep your eyes peeled for secret rocks. they are much more common than you might think
*unlock abadon asap (its by far my favorite item)
*if i have curse of the blind and enough health i will still make devil deals.
*If you have 1 heart containor you can still pick up an item that requires 2 hearts without losing your soul hearts. So for this reason and the likelyhood of guppy or abadon i beleive the ideal amount of health you should have to enter a devil room is 2 and any amount of soul hearts or 3 (if you have no soul hearts) and i often base wether i pick up boss rewards befor entering the devil room off of this.

You can fight mega satan and lamb/??? in the same run.

if you have the key after you kill ??? or the lamb you can just leave the room and then head back and kill mega-satan. So it make sense to always go for a mega-satan run on character you havent beatin him yet on.

learn your transformations

learn your transformations and almost always pick up an item if its part of a set. Even if its a spacebar item you wont use and even if its seamingly bad like guppys tail, guppys hairball, magic mushroom, and puberty pills.

F*CK bobs brain, BBF, and one makes you larger pills (though one make you larger pills suposedly dont increase your hitbox)

Challenges

Pick challenges that you think have dope rewards and unlock those asap. for me its 2,6,7,8,9,14,17,18,29,31, 32, and 34

[link]

lucky coins

Unlock these ASAP

Sacrafice rooms in afterbirth+ are f*cking awsome

if you can damage yourself on the spike 7 or 10 or 11 times without ending your run ♥♥♥♥♥♥♥ do it

Checkout this guide. https://steamcommunity.com/sharedfiles/filedetails/?id=866011767

it just has alot of less known tips like how if you use an item that spawns hearts on the floor in a super secret room that starts with hearts on the floor they will spawn as that type of heart. For example if you use The lovers in a super secret room where when you enter theres an eternal heart, the 2 hearts you spawn will be eternal hearts.

platinumgod.co.uk

This website is amazing check it out.

Also if you didnt know you can sort by colors.
And at the very bottom they have a key for dice rooms and pills.

SteamSolo.com