Overview
My “guide” is just a small quote I found online to solve a glitch in one of the optional quests.
Workaround:
“If you made the mistake of talking to her about HELIOS before you recruited ED-E and the dialogue wont come up, you can instead travel to FORT MCCARREN. In the AIRPORT building to the south (inside McCarren walls), the rooms with the lab equipment on the ground floor on the south east corner, you’ll find a man named THOMAS HILDERN and he will talk about HELIOS as well. From there you should be able to progress with the quest in the same way as if you talked to the Old Lady. Worked for me!”