The Bindening™ – A Comprehensive Guide to Everything Isaac: Rebirth

Overview

This guide is a follow-up to a guide created by Two of Diamonds/スydonia called “The Bindening™: A Comprehensive Guide to Everything Isaac” which explained everything about the original The Binding Of Isaac. This guide will be focusing on TBoI: Rebirth, Afterbirth, Afterbirth+ and Repentance

ANNOUNCEMENTS

This is the main hub for news regarding upcoming/done massive changes to this guide, and the other ones. I recommend to check this section from time to time.

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Announcements flushed.
For a period, which may last between 2 days to the end of the month, the whole item section will be nigh-unusable, possibly even gone entirely, due to the renovation. The same will apply to the trinkets section

Some of you may have already noticed, but Fandom, the service responsible for hosting and managing all of the wikis for various games, has pushed out a new UI, which is set by default from this day for all users of the service.
If you do not like the new UI, and want to go back to the old one, you can go to your preferences, navigate to the Appearance tab, and change the theme from FandomDesktop to HydraDark (AFAIK, this requires you to have a Fandom account).
Saving the preferences will revert the changes made by the new UI.

The items section is almost finished. Still need to add special items. Should be done in a while.
Either way, all items are catalogued in the guide and ready to be looked up.
Please report any mistakes.

The renovation is officially DONE! New visuals, repentance content, everything. It’s all done.
Frequent guide updates will most likely cease from now on, and I’ll only return whenever I feel like there’s something that needs an update. It’s certainly been an interesting journey. Farewell.

Note

This guide is literally my attempt of compressing an entire wiki into a single Steam guide.
To search for the thing you need, use the search function by clicking CTRL+F

Please report any mistakes in the guide comments, since there are bound to be some; I’m only a human after all. By reporting mistakes, you’re helping out the guide by a ton

Introduction

This is a guide that aims to explain everything in the game, including content from DLCs.
From the environment and characters to items and bosses. The guide has it all… or should, at least.

This guide automatically assumes that you have all DLC installed.
For obvious reasons, there will be spoilers for all the endings, bosses etc.; you have been warned

The information in this guide is partially based on my own experience with Isaac and information from the official The Binding Of Isaac: Rebirth Wiki[bindingofisaacrebirth.gamepedia.com]

Steam allows sections inside guides to have a maximum of 8’000 characters. This has forced me to split certain sections into parts. This is especially noticeable in large sections, like Items, Trinkets, or Achievements

Because of the guide’s size, some images may not load correctly. This issue seems fairly rare though.

Index

Here you can take a quick look on what will be looked over in the guide

• Environment
  Things such as rocks, poops, or fires than can block your way or hurt you.

• Pickups
  Different pickups and chests.

• Consumables
  A different type of pickup which disappears after use.

• Attributes
  Different stats and an explanation on what they do.

• Characters
  An in depth look at different stats the various characters have and what makes them unique.

• Floors
  All of the floors in the game, along with their general themes, rules, enemies and what not

• Special Rooms
  All of the special rooms in the game and what they contain

• Deal Rooms
  An overview of a subdivision of special rooms which appear after defeating the floor’s boss

• Curses
  Different curses which can hinder the player during their run

• The Map
  Quick overview of the in-game minimap and its contents

• Victory Laps
  What victory laps are, and how to start them

• Modes
  Different modes, which make the game harder.

• Machines
  Machines and beggars the player can use that can either benefit them or hinder their progress

• Rooms
  A quick explanation on the different special rooms.

• Deal Rooms
  Rules of Deal Rooms, what they are, and what they require to spawn.

• Tear Effects
  Different effects your tears may have, whether they may be positive or negative.

• Item Pools
  An explanation on what Item Pools are and how they work

• Items
  A list of EVERY item in the game sorted alphabetically and by their item pool

• Trinkets
  A list of every trinket in the game sorted alphabetically

• Transformations
  Different abilities characters acquire after picking up a certain set of items sorted alphabetically

• Champions
  An explanation, on what champion monsters are

• Enemies
  A list of every common enemy in the game sorted by the category they belong in

• Mini-Bosses
  A list of every mini-boss and their super version sorted alphabetically

• Bosses
  A list of every boss in the game with places where to find them and how they attack

• Final Bosses
  A list of every final boss in the game with places where to find them and how they attack

• Achievements
  A list of all achievements, and their unlock requirements

• Challenges
  A quick look at all of the challenges, what they start you with and what you unlock for beating them

• Completion Marks
  A section, which explains the post-it notes on each character, and why would you want to fill them all up.

• Secret Seeds
  Inputting some special seeds in the main menu unlocks special effects that you can use in your run. This section lists all of the 72 secret seeds

• Debug Console
  A mini-guide on how to activate the debug console, and what commands you can type in it

• Note Dump
  A section hosting notes, tips or trivia pieces which could not be fit into the guide

• Special Thanks
  Credits to people/websites that helped me with this guide

• Changelog
  List of changes made to the guide

Environment – Introduction

Environmental objects are obstacles and other things found throughout each room in the game. Some hinder your progress, some may help you out. All of them are listed down below.

Environment – Rocks

Rocks are the most common obstacle you’ll find in the game. There are multiple types of them, including:

• Normal rocks
• Tinted Rocks
• Super Secret Rocks
• Bomb Rocks
• Spiked Rocks
• Pots
• Buckets
• Mushrooms
• Skulls
• Marked Skulls
• Polyps

Their apperances, properties and habitats are listed in the table below

All of the rocks below block the player and their tears. This can be bypassed by having flight and spectral tears respectively. All of the rocks below can be destroyed by explosions, and can fill gaps unless specified otherwise. These notes have been added to avoid needless clutter in the table

Environment – Fires

Fires, just like rocks, are also a common obstacle. There are 5 types of fires, including:

• Normal fires
• Red fires
• Blue fires
• Purple fires
• White fires

All of them are listed in the table below.

All of the fires below block the player and their tears. Tears can pass through campfires if they’re piercing or spectral. This note has been added to avoid needless clutter in the table.

Environment – Poops

Poop is the third of the four common obstacles in the game. There are 9 types of poop, including:

• Poop
• Corny Poop
• Red Poop
• Golden Poop
• Rainbow Poop
• Black Poop (also called Meconium)
• White Poop
• Giant Poop
• Charming Poop

All of them are listed in the table below

All of the poops below block the player and their tears. This can be remedied by flight and spectral tears respectively. All poops can fill gaps unless specified otherwise. This note has been added to avoid needless clutter in the table.

Environment – Gaps

Gaps are the last of the four common obstacles you’ll encounter. They block the player, just like rocks, but let projectiles go through.

Gaps will most of the times block the player from accessing a certain area, which may contain valuable pickups.

Gaps can be filled, enabling the player to walk over them, if a bomb blows up a rock adjacent to the gap. The bomb must be on the opposite side of the rock from the perspective of the gap, as pictured below.

Gaps can be sometimes filled with water, or lava. This is purely cosmetic, and the gaps still need to be filled with rocks for the player to be able to walk over them

Environment – Creep

Creep is a puddle of liquid, which has an effect on the player, and occasionally enemies. Creep which affects the player flickers, while the creep that doesn’t, does not flicker. Enemy-spawned creep disappears immediately after the room is cleared. The effects of creep can be avoided by having flight, or the Callus trinket. There are ten types of creep in the game, these are:

• Red Creep
• Green Creep
• Yellow Creep
• Black Creep
• White Creep
• Blue Creep
• Grey Creep
• Orange Creep
• Brown Creep
• Static Creep

All of them are listed in the table below

Environment – Spikes

Spikes can be divided into two groups: stationary spikes, and moving spikes.

Stationary spikes can be walked over, but will damage the player for one full heart in the process. This can be avoided by having flight, the Callus trinket, the Orphan Socks item, or any sort of method to gain invincibility, such as the Book of Shadows. Spikes, just like gaps, will often block the player from accessing certain goods.

Moving spikes will damage the player for just half a heart (full heart in Chapter IV and beyond), but they, as the name suggests, can move. Having flight, Callus or Orphan Socks doesn’t protect the player from damage the moving spikes deal, although Flat Pile or any form of invincibility still nullify them

Stationary spikes

Moving spikes

Environment – Turrets

Turrets may be the most annoying obstacle of them all. They are stationary, invincible stone sculptures, which hinder the player, whether it be by direct or indirect damage. They can actually be killed under specific circumstances, for example by the Euthanasia item or the Chaos Card. There are an astonishing 11 types of turrets, including:

Environment – Shopkeepers

Shopkeepers are environmental objects, that do not interact with the player at all.
However, they can be killed, usually by blowing them up (they can also be killed by fire, Mom’s Foot, or a Holy Light beam). Killing shopkeepers increases Deal Room chance, and may cause them to spawn rewards.
Shopkeepers usually appear in Shops and Secret Rooms.

There are 4 types of shopkeepers, 2 of which need to be unlocked for them to spawn.
All of them are listed down below.

* – Unlocked by donating 234 coins to the Greed Donation Machine
** – Unlocked by donating 10 coins to the Greed Donation Machine

Environment – Other

Here are the other environmental objects that were too insignificant to have their own section.

Gas

TNT

Buttons

Blockers

Teleporters

Cobwebs

Dirt Patches

Ball and Chain

Spikeball

Pickups – Introduction

Pickups are minor items that can be found throughout a run.
They can be found from various sources, including:

• Room clears
• Bosses
• Machines
• Beggars
• Buying them in Shops
• As a pre-defined spawn in certain room layouts
• Active/passive items

Pickups – Hearts

Hearts are used to refill your health. There are twelve types of them, including:

Pickups – Coins

Coins serve as currency in the game. They can be used as payment when using Machines, Beggars or inside Shops.
There are seven types of coins in the game, including:

Pickups – Bombs

Bombs are a pickup, which can be used to grant access to certain areas or as a weapon. They can be dropped by pressing E, and will explode shotly after, destroying any breakable tiles within its range and dealing 100 damage to any entities within the range of the bomb.
There are eight bomb types in the game.

Tainted ??? uses poop as a replacement for bombs, these will be listed in a separate table

Tainted ???’s bomb pickups

Pickups – Keys

Keys are used to grant access to certain areas in the game. There are only 4 types of them.

Pickups – Batteries

Batteries recharge your active item charge. There are four types of them.

All batteries cannot overcharge unless specified otherwise

Pickups – Chests

Chests contain a set of pickups (or rarely items) when opened. Most chests have specific requirements for them to be able to be opened. There are an astonishing 11 types of chests in the game.

Pickups – Sacks

Sacks are pickups, which spawn more pickups when opened. There are two types of them

Consumables – Introduction

Consumables are a subdivision of pickups. They are pickups, which can be used only once (by pressing Q) under normal circumstances. They have their own slot in the bottom-right corner of the HUD.

Consumables – Tarot Cards

Tarot cards are the most common card-type consumable you’ll find. They have moderate effects.
There are 22 different tarot cards.

The effects of tarot cards are boosted if the player has the Tarot Cloth item. The boosts will also be listed.

Consumables – Reverse Tarot Cards

Completing most repentance challenges or defeating Ultra Greedier with tainted characters unlocks reversed tarot cards. These tarot cards have unique effects, ranging from extremely good to run-ending.

Reverse Tarot Cards when laying on the ground have a more reddish tint than normal tarot cards.
Their icon in the HUD is also upside-down as opposed to normal tarot cards.

Reverse Tarot Cards just like their normal counterpart, mostly get affected by the Tarot Cloth item. Its effects will also be listed.

All of the reverse tarot cards need to be unlocked to be able to acquire them. The unlock requirements will be in a separate section right after this one

Reverse Tarot Cards

Consumables – Reverse Tarot Cards Unlock Conditions

Mini-section displaying unlock conditions for the reverse tarot cards.
Couldn’t fit it in the main section due to the character limit

Unlock conditions

Consumables – Playing Cards

Playing Cards are rarer than tarot cards, and because of that, they have slightly stronger effects.

Playing Cards are unaffected by Tarot Cloth

Consumables – Special Cards

Special Cards are even more rare, but have even more powerful effects.
There are 14 different special cards in the game.
Special Cards got various backs alongside having different fronts. Both will be showcased

Consumables – Runes

Runes are unique, decently powerful consumables, which are a rare find.
There are 8 main runes and 3 miscellaneous runes.
The main runes can be divided into left-pointing runes and right-pointing runes.

Left pointing runes

Right pointing runes

Miscellaneous runes

Consumables – Soul Stones

Soul Stones are powerful consumables, which are relatively difficult to unlock.
Unlocking them requires the player to beat Boss Rush and Hush as a specific Tainted Character.
Doing so will unlock the corresponding stone.

There are 17 soul stones in the game.

Consumables – Pills

Pills are common consumables that can affect the player’s stats or give them temporary effects

There are 50 pill effects in the game but only 13 are chosen to spawn in a run, so it is not possible to see every pill effect in one run.
An exception to this rule are the rare gold pills, which can be used multiple times before they disappear, and can have any of the 50 effects each time it’s used. They need to be unlocked via defeating Mega Satan as Tainted Cain

Apart from gold pills, there are also horse pills, which have a more powerful effect than its normal counterparts. They need to be unlocked via defeating Mega Satan as Tainted Eve

All of the 50 effects, along with their horse pill variants will be listed in the section below.

Consumables – Pill Effects

Consumables – Pill Effects/Notes

This section lists all the notes for the pill effects, which couldn’t be fit into the previous section because of the character limit

Unlock methods

Notes regarding pill effects

Attributes

Apart from items, attributes are what make up your character. They detemine how durable you are, how dangerous you are, etc., and can be influenced by most items, or even consumables.

Attributes can be divided into character attirbutes, tear attributes and miscellaneous attributes.
You can see your current attributes in the pause menu, or on the Found Hud, located in the game’s settings menu.
The pause menu, nor the found hud show all attributes however, some of them are hidden, and will be described in a table of their own.
All will be described below

Character attributes

Tear attributes

Other attributes

Hidden attributes

Characters

There are 17 characters in TBoI: Rebirth that you can play as when you unlock them.
Each character has their own unique stats and items that they start with.
I will divide this section into a few categories as there are too many characters to fit in one table.

An underlined parameter means, it’s better than default
A parameter in italic text means, it’s worse than default

NOTE: Tables match Repentance values; if you don’t own the Repentance DLC, you’ll have different values

Characters from the original TBoI:

* – if unlocked

Characters added in the TBoI: Halloween Update:

* – if unlocked

Characters added in TBoI: Wrath of The Lamb:

* – if unlocked

Characters added in TBoI: Rebirth:

* – if unlocked

Characters #2

Characters added in the Afterbirth DLC:

* – if unlocked

Characters added in the Afterbirth+ DLC:

* – if unlocked

Characters #3

Characters added in the Repentance DLC:

Tainted Characters

Tainted characters are versions of the normal characters, which are different in a certain way, which usually mean they’re harder to play with than their base versions.
They’re unlocked by using the Cracked Key, or the Red Key on the top-most left wall in the left narrow corridor located inside Home, and touching the tainted character laying on the ground.

Tainted versions of the OG Isaac characters

Tainted version of Eve

Tainted version of Samson

Tainted Characters #2

Tainted versions of TBoI: Rebirth characters

Tainted Characters #3

Tainted versions of Afterbirth characters

Tainted versions of Afterbirth+ characters

Tainted versions of Repentance characters

Characters – Birthright

Birthright is a special passive item, found in shops, which grants effects based on which character you’re playing as.
All of the effects are listed below.
Roughly half of the effects are not implemented yet.

Birthright – Normal Characters

Birthright – Tainted Characters

Characters – Tips #1

Certain characters need to be played in a different way to benefit from them. This section lists some of such ways/tips for each character.

Isaac
No tips for him, really. Just play the game normally. If you have the D6 unlocked, reroll any active items you find, since it’s usually better to keep your D6 over anything else.

Magdalene
The biggest upside to Magdalene is her high health and the Yum Heart. This, paired with the Full Health pill (assuming it is unlocked already by completing challenge #32), can let you use the Sacrifice Room enough times to proc the Angel Room item spawn (7th sacrifice, 33% chance to spawn the item, 66% chance to spawn soul hearts instead).
Generally, you’ll want to stock up on red heart containers, considering you can regen red health with ease via the Yum Heart. Alternatively though, you could use the extra health to make deals with the devil with less risk.

Cain
Cain’s biggest upside is his Lucky Foot, which turns all pill effects into good/neutral ones, eliminating the bad ones entirely (also increases the chances of winning a Shell Game or any Slot Machine game, if you’re into that sort of thing). Considering pills are quite common in the game, you can have huge stat boosts from just the pills themselves. This makes items like Mom’s Bottle of Pills, Placebo, or Mom’s Coin Purse actually worth taking. The Lucky Foot effect also affects golden pills, making them unable to grant bad effects, turning them into extremely valuable and strong consumables. Cain also has a relatively high damage multiplier, making damage-ups significantly more effective. His Paperclip trinket also usually means you’ll be decently high on keys throughout the run.

Judas
You can consider Judas as a sort of “glass cannon” character; high damage, low health. This makes damage-ups very valuable, as generally they’ll have a stronger effect. Focus on getting health ups, so you don’t die in two hits. Devil Rooms are not recommended due to this. His Book of Belial is best used in large rooms and boss rooms. It is also very strong in Boss Rush, as continuous uses of the book in the same room grant further damage bonuses.

???
??? is baby’s first challenge character. His inability to have red health makes taking damage that much more irritating, and also makes Devil Rooms completely redundant. Items that can regenerate armor health, such as the Book of Revelations or The Nail are very strong. The Satanic Bible is also a viable choice, but it’s recommended to use it only after beating the boss, so you don’t turn the pedestal item into a deal with the devil.

Eve
Eve starts out weak, but if she goes into her ♥♥♥♥♥ of Babylon state, she becomes significantly more powerful. Because of this, unlike with the other characters, Devil Rooms are your best friend, since they let you get rid of your red health with ease. Health ups are more harmful than helpful for the reasons mentioned previously. If you don’t want to get rid of your red health however, you’ll have to put up with the 0.75x damage multiplier, which makes damage-ups less impactful, but reduces the risk of death, since you have more health to work with. The Book of Revelations is extremely strong with Eve.

Samson
Samson is kind of a bleak character. A slightly stronger Isaac and that’s it.
Going into the floor’s curse room can give you a free damage-up alongside the room’s pickups/items, assuming you are willing to sacrifice your health.
The Dull Razor is a sort of common and particularly powerful item for Samson, since it procs the Bloody Lust effect without any drawback, and has a measly 2-room charge.
The Blood Oath can also be a good item, since it synergizes extremely well with Bloody Lust, granting an enormous damage-up

Azazel
Azazel’s biggest downside is his range, which is extremely small. A range this small just barely lets you kill Boom Flies without getting hit by the explosions. Because of that, range upgrades are extremely important when playing as Azazel. ~10 range gives you a range you can work with.
You’d think that with Azazel’s default short-range brimstone, it would be pointless to aim for the normal Brimstone, but you’d be wrong. The normal Brimstone replaces Azazel’s short-range version and gives him full range, making Brimstone a very valuable item in any Azazel run.
Azazel apart from his brimstone also has flight, allowing him to hide over rocks and pick off enemies from a “distance”.

Lazarus
Lazarus is basically a worse Isaac… until you die. It’s generally recommended to proc the extra life from Lazarus’ Rags to get the stat increases. After that, it’s a normal TBoI run.
It’s heavily recommended to beat challenge #31 to unlock the Anemic item for Lazarus, since when playing as Lazarus Risen, the creep is being left behind constantly, instead of when damage has been taken.

Eden
There’s not much more to this character than resetting the run until you get a decent start.

The Lost
The Lost is arguably the most well-known challenge character in the game, being able to be killed by virtually anything in just one hit. Risk is not a thing with this character; exploit every aspect of the game to make sure you don’t lose a good run. Also make sure you unlock the Holy Mantle for him first by donating 879 coins to the Greed Donation Machine; a tedious feat, but one worth doing. His flight and spectral tears allow the Lost to get otherwise inaccessible pickups and kill enemies from a safe place. Any items which grant survivability, such as extra lives (Dead Cat, 1up!) or Psy Fly/Bot Fly are very valuable when playing as the Lost. Assuming the Holy Mantle is unlocked, the player can make a risky, yet sometimes rewarding move, by going into the Curse Room for free because of the Holy Mantle. This move is risky since enemies are a common sight in these rooms, and if you lose the mantle before exiting the curse room, you will die no matter what when trying to escape, unless there is an adjacent secret room.

Lilith
Lilith’s quirk is being blindfolded, and as such, being unable to fire tears. Instead, she uses her Incubus familiar to do the job. Apart from this, there’s not much else. Good items for Lilith are BFFS!, which acts as a free 2x damage up, and Revelation, since it lets Lilith fire a laser straight out of her body, eliminating the need to screw around with the Incubus.

Keeper
Keeper is a worse Lost, that’s it. Sure, he can afford to get hit, but not by much. One thing the Keeper’s got going for him is his triple shot and a high damage multiplier, making damage-ups and tear status effects that much more strong. Devil Deals are particularly strong with the Keeper, since when playing as him, deals with the devil cost money instead of hearts.

Characters – Tips #2

Apollyon
Apart from possessing the Void, and having slightly lower health, Apollyon is identical to Isaac. You can use the aforementioned Void to suck up passive items you’d not want to take, and exchange them for stat upgrades instead. Suck in active items only if you know what you’re doing.

The Forgotten
The Forgotten can be a very strong character if used properly, the biggest upside being able to get pickups with the soul form, which would be unavailable otherwise. There are many other benefits though, such as being able to use the Forgotten’s empty body as a projectile shield during hard fights. One downside with this character is that you have half the max health you would usually have per form, making you much more fragile, unless you switch to the soul before the body takes a killing hit and vice-versa, allowing you to keep fighting for longer. For the body, range upgrades are pretty good, since with your bone club you’re limited to melee range only. 10-12 range is optimal. For the soul, anything which works with your normal Isaac works just as well with the soul.

Bethany
Bethany’s biggest downside is being unable to have armor health, or the common kind at least. This makes getting deal rooms extremely difficult, since you have no room for error when fighting enemies. I said “or the common kind at least”, since Bethany can still have Rotten Hearts and Bone Hearts, which act as armor hearts and prevent the loss of the deal room chance. They’re a relatively rare find though. Her Book of Virtues, or rather the wisps it spawns can be very helpful, as they not only act as additional DPS but also protect you from projectiles, which may save your deal room chance every now and then. The wisps can also out-damage you if used with certain active items. A good example is the Tear Detonator wisp, the projectiles of which can be detonated just as well as your normal tears. Not only that, the wisp will detonate all player-spawned projectiles on screen when it dies. These wisps will more often than not cover the entire screen with tears, especially on boss fights. Another good example, and certainly a more well-known one is the Shoop da Whoop wisp, which will fire a laser if Shoop da Whoop is used by the player. A ton of these wisps and a few soul heart charges can melt most bosses in a few seconds. These were just two examples, and there are many more.

Jacob & Esau
Jacob & Esau seem extremely hard at first, mostly because you get half the items per character, which more often than not completely kills your run. However, if you go for the full alt path from Basement I, you can remedy that completely, and have a working run. You can do that by aligning the two characters horizontally, or veritcally, depending on the orientation of the two items, and running into both of them at once with the two characters. This will grant the two items, one per each character. There’s not much else to this character, other than using bombs to your advantage; bombs are significantly more powerful with J&E than with any other character, since both Jacob and Esau place a bomb, at the cost of just one. This may not seem like a large thing at first, but it is extremely helpful. There is a surprising amount of times, where you need two bombs to gain access to certain pickups, which can be accessed with just one bomb as J&E. The double bomb also helps greatly with bosses, especially the early ones.

Tainted Characters – Tips #1

Tainted Isaac
Even when tainted, Isaac is still boring. Play the game normally, switch out anything useless for something useful.
The effects of some items are permanent, even if you leave them behind. This happens mainly with HP upgrades but can happen with other items, such as the Red Stew, or the Consolation Prize. This also goes for any items added directly to the character, such as familiars from the Soul of Lilith.

Tainted Magdalene
Because you constantly bleed out, you can play Tainted Maggy in two ways. You can either rush through each floor, trying to keep your HP at the highest point it can be at, or you can take your time, and think everything through, which leaves you at little to no HP at all times. In either case, you should stock up on health upgrades; one thing that Tainted Maggy’s got going for her, is that the bleedout health functions as armor health, even when red. This allows you to use your melee attack regardless if you want to keep your deal room chance or not.
Also make sure to check every shop, as it can contain the Sharp Plug item. With Sharp Plug, you can recharge your Yum Heart at a maximum cost of two hearts. Since T.Maggy’s Yum Heart heals you for two hearts, you can spam the item endlessly, and because damage from Sharp Plug triggers invincibility frames, you’re free to use your melee attack free of charge. In Layman’s terms, it turns you into an invincible killing machine.

Tainted Cain
This character is basically having the debug console as a gameplay feature. You can craft virtually (almost) any item with your Bag of Crafting, if you get lucky with the pickups you get, and because of that, there’s tons of room for creativity. The recipes for items are pre-determined*, meaning you can just go look at the wiki[bindingofisaacrebirth.fandom.com] and choose what you want to craft like you’re in a supermarket. Due to some questionable design choices, powerful items like Rock Bottom or the Red Stew have decently cheap crafting recipes, so I recommend you unlock these first before attempting Tainted Cain.
If you don’t want to look at the recipes, you can just play the game normally, you’ll hit a good recipe eventually. Rarer pickups result in better items most of the time
* – bound to be changed in a future hotfix, but I’ll keep it in here for now

Tainted Judas
Apart from your Dark Arts item, there’s not much else to this character. Dark Arts is best used to traverse through spikes without getting hurt, or to kill large swathes of enemies/projectiles in one move, granting you a huge damage boost. Items which block projectiles are not recommended, since they persist when the player is using Dark Arts. This will usually result in the item blocking many projectiles, which would give you tons of free damage otherwise.
Just like Tainted Maggy, Tainted Judas also has an item which guarantees a win, and that is the Converter. The converter converts a soul/black heart into a health upgrade, and since health upgrades for Tainted Judas default to black hearts, the Converter has no effect on the health of the player. For some reason though, converting a black heart still activates its effect, meaning that each use of the Converter is a free 40 damage to all enemies in the room. After you get the Converter, it’s just a matter of how fast you can spam your active item button.

Tainted ???
Tainted ??? is a tough character to play at times for the same reason as regular ???, and that is the lack of red health, but on top of that, Tainted ??? also has worse fire rate, and additionally a little something, which I’ll talk about later. To compensate, Tainted ???’s got an arsenal of different poops which you can use by pressing Q. There are eleven different poops T.??? can use, including:

• A normal poop, which can deal 15 damage to enemies when thrown at them
• A corny poop, which spawns up to three blue flies.
• A stone poop, which is very durable, but has the same properties as normal poop otherwise.
• A green poop, which constantly leaves behind trails of explosive and poisonous gas.
• A red poop, which has a fire inside of it, which can damage enemies upon contact and explode any explosive gas
• A black poop, which constantly leaves behind black creep and deals 10 damage to all enemies when destroyed
• A white poop, which behaves identically to the normal white poop
• A bomb, which explodes 1.50s after spawning
• The explosive diarrhea pill effect
• A fart, which deals poison damage to nearby enemies and spawns a cloud of explosive gas
• A trail of creep, which deals immense damage to enemies stanidng on it and gives stat boosts to the player when they stand on it

That little something I talked about earlier while discussing T.???’s downsides was the amount of explosive gas he spawns. Even with only two poop types which actually do that, the amount of explosive gas you release is tremendous. This usually results in tons of self-damage, as campfires are not a rare sight in any room and will explode any explosive gas they come into contact with. Because of this, hoarding health with Tainted ??? is even more important than with the normal version.

Tainted Eve
Tainted Eve is a weird one; some people think she’s overpowered, some people think she’s underpowered. She can fire continuously to create a blood clot, which behaves like what you’d get from combining Incubus and Jacob & Esau controls. With enough of these, you can become incredibly strong, being able to clear every room in just a couple of shots. You can choose two ways of creating clots; the safe one, which involves turning only excess health into clots, and a bit of your own health if you feel confident, or the risky way, which involves turning ALL of your health into clots from the get go; this method gives you significant firepower, but turns you into a worse version of the Lost. Which way you choose is up to you, but what applies to both methods is good luck. Just like with any other character you need some good RNG to get a run that will end up killing an endgame boss. This luck is slightly more required for Tainted Eve, as usually during final boss fights you’ll lose most of your blood clots no matter what; the only reason why I beat Delirium with Tainted Eve is because Eve was strong enough on her own in my run.

Tainted Samson
The berserk mode is a nifty tool in the early floors, but becomes increasingly more annoying as you get more powerful on your own. Focus on items that may be a great help when in berserk, a.k.a. any damage-up

Tainted Azazel
Azazel but you’re not limited by range anymore and that’s about it. The lack of flight makes pickup hoarding slightly more difficult but it’s worth the unlimited range. Make sure to make good use of your hemoptysis. Also keep in mind that hemoptysis can deal great damage by itself, especially when you have multi-shot items, such as the Inner Eye, Mutant Spider etc. It can also be used to create some distance between you and the enemy due to its heavy knockback.

Tainted Lazarus
Imagine Jacob & Esau without any benefits of Jacob & Esau. That is Tainted Lazarus. Because of how he works, he needs double the amount of good items to keep himself alive, which in turn requires immense luck. I recommend you to not bother with this character unless you absolutely have to, he’s supposed to get a rebalance soon.

Tainted Characters – Tips #2

Tainted Eden
Tainted Eden can be pretty fun. His quirk involves the player rerolling their items each time they get hit. This in turn sort of forces you to play every run, since you might just get that godlike combination and not worry about getting hit ever again, and getting as many passive items as you can maximise these chances. I recommend you go for Angel Rooms; health is hard to come by as Tainted Eden, since it cannot be easily gained, but can be easily lost due to the rerolls, and trading your health just makes the situation worse. Even then, Angel Rooms are more likely to grant you powerful items anyway. Additionally, items from the Devil/Curse pool can get rerolled into Dead Cat, which will annihilate your HP and kill your run no matter in how good of a situation you are. Try to aim for as many character-bound heart containers as possible. These will mainly come from eternal hearts, but may come from items like Experimental Treatment, the heart containers of which do not get rerolled. You may have heard of getting as many soul hearts as possible with Tainted Eden, to keep the health situation in check, but the soul hearts can be rerolled just as easily if you get unlucky and get a load of HP upgrades.

Tainted Lost
If your definition of fun in this game is getting some OP, or just straight up wacky item combiniations, then this character is the perfect choice for you. Good runs are significantly more likely to happen with Tainted Lost, in exchange for the complete lack of health, and even the Holy Mantle. The key to this character is literally just practice, and semi-good RNG. It doesn’t even matter whether you want Angel Rooms or Devil Rooms; with Tainted Lost, both choices are fine (although if you have Damocles unlocked, Devil Rooms are significantly better, considering how common Damocles is in the Devil Room pool and how extremely powerful it can be with Tainted Lost. Make sure you have it unlocked, it’s very worth it. However if you still want to stick to the angels, consider heading for the Beast as Tainted Lost first, as this unlocks Sacred Orb, another very good item).
When playing as Tainted Lost, tear effect items, such as the Holy Light, Common Cold, Sinus Infection etc. are particularly powerful, considering T. Lost gets the Perfection trinket every time after defeating the Caves I/Downpour II boss, which grants a free +10.00 luck at the cost of your trinket slot. Because of this, Mom’s Purse is significantly more valuable, as it lets you carry an additional trinket alongside Perfection. Tick-based items such as Brimstone, or Tech X get indirectly buffed because of this as well, since they have a chance to proc the tear effect with each tick of damage they deal. Be careful around convert all cards when Perfection is in the room, as it will convert Perfection into the respective pickup. I’ve done this by accident more times than I’m willing to admit.
As with the normal Lost, exploit the game to its fullest, take cover behind each safe rock, pick enemies from the largest distance you can manage and keep a very strong mental note of any red poops, fireplaces, spiked rocks, slides, grudges and the such; they’ve ended too many of my runs, each of which were super good until I ran face first into a slide and killed myself on it.
Any card-generating items are significantly better now, since they have a higher chance to generate Holy Cards, while Little Baggy is even worse than it was before.
Make sure to not pick up many items which would create tons of visual clutter on screen. The last thing you want is to not know where you are in the room. Anything that causes uncontrollable damage is bad as well; I’ve been killed by too many Boom Flies which died right in my face because my Demon Baby decided that was the best enemy to attack.

Tainted Lilith
The strategy with Tainted Lilith is sort of similar to how you play with normal Lilith, except this time you can also damage enemies directly by slinging your fetus at them. As disgusting as that sounds, it’s a pretty good source of damage early on, and if you get some damage-ups, it can carry you even to the endgame. Try to also get out of slow speed.

Tainted Keeper
Not much more to this character than to just keep trying. At least this time you’ll be having fun. I was, at least. Each run is worth playing considering you have to kill enemies to get items. I recommend skipping the first treasure room to get a planetarium later on, as most likely you’ll get equally as good items in the shop.

Tainted Apollyon
Even being tainted did not help Apollyon with being unique. He’s still the “Isaac but has the Void” but this time you have the Abyss. Suck in bad items and take the good ones. Focus on getting damage ups, as your locusts scale with your damage.

Tainted Forgotten
Tainted Forgotten can be quite fun, even with the challenge he presents, although winning with him mostly boils down to getting lucky with damage ups and multi-shot items, as these are the biggest game changers when playing as him. Try to get familiar with how the character works, since at first it will catch you off guard. If I had to explain how Tainted Forgotten works, imagine the skeleton functioning as THE player, who can control everything, pick up anything, and generally just do everything a normal character would (this includes bomb placement), except for moving around. For that, the soul comes into play. The soul can throw the skeleton around in order to move it around and deal damage, but can also open doors, go through them and pick up pickups, and items, which get transferred to the skeleton. Be very careful around trapdoors to the next floor, as any of the two entities can trigger them. Tainted Forgotten can also move extremely fast through rooms, by throwing the skeleton into the doorway to the next room. When you get it down, it’s the best thing about this character, since you can backtrack with almost no penalty in regards to getting to Boss Rush and/or Hush.

Tainted Bethany
Tainted Bethany even with her Lemegeton still has to rely on actual items to get far in the game. Do not fully rely on your wisps as they will all die on final bosses if you haven’t got any sort of invincibility. The best way to use the Lemegeton is to use it only when it’s full with actual charge, and not the blood charges. The blood charges then can be used for the Lemegeton in an angel room, to get tons of good items. For this reason, items that grant you red health are really good (e.g. the Leech).

Tainted Jacob
Honestly? I don’t even know. This character was not designed to be fair it seems. You can either stick to how the character works, or exploit your way out of him, depending on your moral compass.
If you want to take the easy way out, you can kill Dark Esau and quit the game during his death animation. When you continue, Dark Esau will be gone but you will not be turned into the lost form.
This is the best, and the most scummy way to eliminate Dark Esau completely, but there is another one, involving the Eraser. The Eraser projectile deals 15 damage to any boss enemies instead of removing them. However, if the Eraser kills the boss with the 15 damage it dealt, the boss is removed regardless. This applies to Dark Esau as well, meaning that if by some chance you manage to get him down to below 15 HP and have the Eraser on you, you can remove Dark Esau for the rest of the run.

Characters – Unlock Criteria

These are the unlock criteria for all characters

The Forgotten:
The process of unlocking the Forgotten is slightly complicated, and is too long to fit in the table.

The Forgotten is unlocked by unearthing him in the Dark Room by using Mom’s Shovel on top of his grave.

Before attempting this, the player must have defeated The Lamb, and unlocked the Negative.
The puzzle can be attempted in both normal and hard mode.

To assemble the shovel, the player needs to beat the Basement I boss in under a minute. After doing so, the player will hear Mom shouting “Isaac!” and some muffled steps.

Going back to the spawn room and placing a bomb there will drop the first piece of the shovel. While having the shovel in your inventory, Mom’s foot will constantly stomp the player every few seconds. Using the shovel prevents that from happening for one room, or one Boss Rush wave.
Make sure to not replace the shovel with any active item, as leaving the first piece behind and exiting the room will make it disappear.

To get the second piece, the player needs to beat the Boss Rush.
The 20 minute requirement does not apply when holding the first shovel piece, and the passage to the Womb will not open until Boss Rush has been defeated
Beating the Boss Rush grants the second piece.
Having the assembled shovel prevents Mom from stomping the player constantly.
The passage to the Cathedral will not be present after defeating Mom’s Heart/It Lives!, forcing the player to go down to Sheol

In the Dark Room there will be an empty room with a lone patch of disturbed dirt in the middle. Standing on top of it and using the shovel unlocks The Forgotten

Floors – Introduction

Floors are.. well.. floors. You need to progress through them to progress in your run.
Floors are divided into chapters, depending on how far they are in the game. Generally, the deeper you go, the harder and tankier the enemies are, along with bosses, and the overall chance to take damage, or even die, increases.
In total, there are 26 different floors, and seven distinct chapters.

Floors – Chapter I

These are all the floors of Chapter I
These floors generally contain simple and semi-fragile enemies and easy bosses.

The first and most iconic floor in the game.

The Basement contains simple enemies, most of them relying on contact to damage the player. The bosses of the floor are fairly simple as well.

The chapter always contains a shop, treasure room and a boss room.
Curse Rooms, Sacrifice Rooms, Vaults/Bedrooms/Dice Rooms, and Challenge Rooms of any type may also sometimes appear.
A Planetarium also has a chance to appear, albeit a very small one, at just 1% in the first floor (notes on planetarium spawn chance can be found in Special Rooms).
(The trend above is continued in the Caves and the Depths, along with their alt-path versions)

The first floor’s shop and treasure room are always open, while the second floor and further chapters require a key to open each room.
The treasure room very often appears near spawn, mostly opposite to the shop, but in rare cases can appear after the shop.

A Deal Room cannot spawn on the first floor, requiring the Joker card or a red chest to get inside it. This is not the case for the second floor. In further chapters the Deal Room will always have a chance to appear.

An alternate version of the Basement, unlocked by defeating all Chapter I bosses at least once

The enemies inside the Cellar are often spiders, but normal Basement enemies aren’t a rare sight either. This makes the Cellar a tougher floor to get through, both in terms of effort and time.

The Cellar’s boss pool is slightly different from the Basement’s, featuring additional spider/ghost-themed bosses, mainly the Widow, the Haunt, Blighted Ovum and also Pin, who is neither a ghost or a spider, but a worm, yet appears in the Cellar only anyway.

An alternate version of the Basement, unlocked by defeating Mom’s Heart 11 times

The floor is themed around fire, and so are its enemies. A burning enemy is a fairly common sight in this floor, and they will usually be slightly weaker than their base version or signifcantly more annoying and tiresome to deal with, no in-between.

Unlike the Cellar, the Burning Basement does not have unique bosses.

An alternate-path version of the Basement, with its access door unlocked by defeating Hush three times.

The water-themed Downpour is a completely different floor from the Basement. It’s accessed by opening the door to it using a key in the Basement I’s boss room.

The enemies inside Downpour are slightly more complex, and usually rely on projectiles to damage the player.

Its level generation is near-identical to the Basement’s.
Downpour II contains a special mirror room, used in the Repentance puzzle.

The floor has some special visual effects, mainly the flooded floor and the occasional lightning strikes.

The bosses in this floor are completely unique. No Basement/Cellar bosses can appear in Downpour and vice versa. Some of this floor’s bosses are shared with Dross though.

An alternate version of Downpour, unlocked by defeating all Downpour bosses at least once.

The sewage-themed Dross is a harder version of Downpour. Its enemies rely on both erratic movement and complex-ish projectile patterns alike to damage the player.

Some rooms in this floor may have an active current running through them, hindering the player’s movements slightly, but also enemies’. Current-possessing rooms are usually 1×1 but can very rarely be of bigger sizes.

The floor features some bosses of its own, mainly Clog, Colostomia and Turdlet.

The floor has some special visual effects, mainly the flooded floor and the toxic(?) gas in the background

Just like in Downpour II, the mirror room appears in Dross II as well

Floors – Chapter II

These are all the floors of Chapter II
These floors generally contain simple, albeit tanky enemies, and semi-difficult bosses.

The second chapter. A step-up from the Basement in terms of difficulty.

The Caves can be entered from Basement II, or Downpour II (Downpour will lead you to Caves II, skipping Caves I)

The enemies inside the Caves are usually fairly tanky, requiring 6 base damage shots on average to kill. This means that you’ll usually spend more time in this chapter than you did in the previous one, by just trying to get to your destination.

In terms of level generation, the Caves are a bit more complex than the Basement. They’re not straightforward anymore in most of the cases, and will branch out in different directions.

Just like the enemies, the bosses in this chapter have their fair share of health as well, making fights with base stats very tedious.

An alternate version of the Caves, unlocked by defeating all Caves bosses at least once.

Not much different from the Caves, other than being more likely to have rooms with spiders.

The floor’s got some unique bosses, mainly the Husk, the Hollow, the Wretched and the Carrior Queen, all themed around decay, except for the Dark One and Polycephalus, which are just sort of there.
The floor also has bosses which are shared with the Flooded Caves, these are the Forsaken and the Frail.

An alternate version of the Caves, unlocked by defeating It Lives! 16 times

The enemies in this floor are usually themed around being drowned/bloated.

The floor’s got some additional visual effects, mainly the flooded floor and the ever-present blue fog/tint.

The alternate-path version of the Caves, with its access door unlocked by defeating Hush three times.

The Mines are accessed by unlocking the door leading to it. This door appears in Downpour II, and Caves I/II, and requires two bombs to be unlocked, just like a Bedroom.

The enemies in this floor are mainly themed around explosions and fire.

The floor’s got some unique environmental objects, such as throwable bombs, enemies in minecarts, or dark rooms.

Mines II contains the minecart room used in the Repentance puzzle. This room only spawns when the player has the first knife piece, it will not spawn otherwise.

The bosses of this floor, just like in Downpour, are completely unique, meaning they can’t appear in the Caves and vice versa. Some of this floor’s bosses are shared with Ashpit.

An alternate version of the Mines, unlocked by defeating all Mines bosses at least once.

The ash-themed Ashpit is a harder version of the Mines, featuring tankier, and heavier-hitting enemies, mainly themed around skeletons, ghosts or fire.

The floor’s got some unique visual effects, mainly a continuous stream of ash running through the screen.
The Ashpit contains the same unique environmental objects, you’d find in the Mines.

The minecart room appears in Ashpit II just like how it does in Mines II.

Floors – Chapter III

These are all the floors of Chapter III
These floors generally contain complex, tanky enemies, and bosses ranging in difficulty from easy to hard.

The third chapter. A significantly harder floor than the two previous ones.

The Depths can be entered from Caves II, or Mines II (Mines will lead you to Depths II, skipping Depths I)

The enemies inside the Depths are sort of on par in terms of health with the enemies from the Caves, but they use more complex attacks in order to deal damage to the player. The difficulty in this chapter mostly comes either from lack of room to dodge, enemy spam, or just complex enemies.

Rooms with traps are not a rare sight in this chapter, and they’re usually pretty bad too.

The trap room above has killed far too many of my runs. As far as I know there is no way to pass through it without taking damage, assuming you don’t blow up the skull.

As said in the main description, the bosses of this floor are either easy (i.e. Monstro II), or tanky and tedious (i.e. the Cage or the Adversary).
The boss of the second floor is always Mom.

As far as level generation goes, it’s usually the same as the Caves’, albeit a bit more exaggerated.
The spawn room additionally tends to be on the edge of the map.

The Strange Door will always generate above the spawn room once Mother has been killed.
This also applies for the Necropolis and Dank Depths, but not Mausoleum and Gehenna

An alternate version of the Depths, unlocked by defeating all Depths bosses at least once.

Just like the Catacombs compared to the Caves, the Necropolis isn’t much different from the Depths.

In the Necropolis there are generally more skulls, death-themed enemies and also more trap rooms.

The floor’s got a few unique bosses, mainly the Adversary, the Mask of Infamy, and also the Bloat and the Pile, both of which are also shared with the Utero and Ashpit respectively.

An alternate version of the Depths, unlocked by defeating It Lives 21 times.

The Dank Depths are a step-up in difficulty from the normal Depths.
The floor features tar-themed enemies, which tend to be significantly tankier.

An alternate-path version of the Depths, with its access door unlocked by beating Hush three times.

The Mausoleum is accessed via the door leading to it. The door spawns in Mines II/Depths I and requires two full hearts to unlock it (with the exception of the Lost and his tainted version, which can open the door for free (the door can also be opened for free with the Sharp Key, Dad’s Key or Mr. ME! items)).

The Mausoleum contains significantly more complex enemies in comparison to the previous three floors. They tend to be slightly tankier as well.

The floor contains a few environmental objects of its own, including Teleporters and Grudges.
The colors are slightly tinted purple as well.

The bosses inside the Mausoleum are very complex, expect to take a few hits if you’re not experienced.
Just like in the Depths, the boss of Mausoleum II is always Mom. In the Mausoleum though, Mom spawns as a harder version of herself, more on that in Final Bosses – Mom.

Unlike in Downpour and the Mines, the Mausoleum hasn’t got a Repentance puzzle room, except for the Mom’s Heart fight that spawns after defeating Mausoleum Mom.

An alternate version of the Mausoleum, unlocked by defeating all Mausoleum bosses at least once.

The torture-themed Gehenna is a harder version of the Mausoleum, and the difficulty spike is more noticeable than with the other alt-path floors.

Its enemies are even more complex than the ones in the Mausoleum, but not by much.

The floor’s got one more environmental object, that’s exclusive to Gehenna, and that’s the Ball ‘n’ Chain. These can be run-enders sometimes.
The colors in the floor are also more saturated.

Floors – Chapter IV

These are all the floors of Chapter IV
These floors generally contain complex and very tanky enemies, but the bosses are on par with the ones in the Depths, sometimes even easier.

The fourth chapter, unlocked by defeating Mom for the first time. Last chapter before you enter the endgame.

The Womb is entered from Depths II/Mausoleum II.

The biggest difference between the Womb and the previous chapters is that Treasure Rooms, Shops and Planetariums no longer spawn. This trend is continued for the rest of the further chapters. This also indirectly results in a lot of dead ends inside the floor.

The enemies inside the Womb are relatively complex and usually very tanky, requiring a heap of hits at base damage to be killed.

Rooms with traps are a normal sight, and usually there is at least one such room in each floor.

The bosses of this floor are relatively simple in comparison to the previous chapters, but will make up for that with tons of HP.

The floor’s got a visual overlay composed of a grain-like layer, which moves across the screen.

The boss of Womb II and its alternate versions is always Mom’s Heart/It Lives

An alternate version of the Womb. This one, unlike the other alternate floors, does not need to be unlocked.

Enemies in this floor are more bloody and/or deformed. Not many other differences.

The floor’s got a visual overlay composed of some sort of bodily fluid, slightly warping the screen and giving it a slight orange tint.

The floor’s got a few unique bosses of its own, including Teratoma, Daddy Long Legs, and also Sisters Vis, the Bloat and Triachnid, which are shared with other floors.

An alternate version of the Womb, unlocked by defeating It Lives 30 times.

Enemies in this floor are significanlty injured and/or scarred. Red poop may sometimes replace normal rocks.

An alternate-path version of the Womb, requiring a special process to unlock it. More on the process in Floors – Unlocking the Corpse. There is no turning back now.

The dead Corpse is a significant step-up in difficulty from the Womb. Its decayed enemies are significantly more complex and most of the times even tankier than the normal Womb enemies.

The floor can be entered only from Mausoleum/Gehenna II.

The floor’s got an an enviromental object of its own; the Spikeball. They’re usually not a big problem, but can become one in rooms with enemies.

The bosses inside Corpse are just straight up unfair, its not even worth talking about them; expect to get hit, a LOT.
The boss of Corpse II is always Mother.

After defeating Mother, there is no way to progress further in the run. The only remaining option is to end the run with the End Chest.

Floors – The Blue Womb

 

An optional chapter, accessed by defeating Mom’s Heart/It Lives in under 30 minutes.

The floor layout is always the same.
One main chamber, with two treasure rooms to the side, a shop below, and the boss chamber above.

The starting room contains 4 golden chests.
Each treasure room has two items to choose from. When one is chosen, the other disappears.
The shop is always fully upgraded, regardless of the unlocked shop upgrades.

The boss room contains Hush, one of the final bosses.
Defeating Hush for the first time will spawn the End Chest, ending the run. Subsequent kills will present gateways to Sheol, Cathedral and the Void.

Floors – Chapter V

These are all the floors of Chapter V
These floors are usually very difficult in runs with little good items.

The dark side, and the beginning of the endgame.

The floor is accessible only after defeating It Lives in Womb II (cannot be accessed if Mom’s Heart has been killed instead, unless the player encounters a devil room after the fight, which will have a trapdoor to the floor.)

The enemy encounters in Sheol are usually very fast-paced, requiring the player to have good thinking skills and reaction times to avoid damage.
As for the enemies themselves, they mostly rely on projectiles to damage the player, but contact-damage-based enemies aren’t a rare sight either. Bosses may often appear in the floor as regular enemies.
Forced damage is not a rare thing in Sheol. Take any of the rooms that have Camillo Jr. for example.

The boss of the floor is always Satan.

The holy side, and the beginning of the endgame.

The floor is accessible only after defeating It Lives in Womb II (cannot be accessed if Mom’s Heart has been killed instead, unless the player encounters an angel room after the fight, which will have a beam of light leading to the floor.)

Unlike in Sheol, enemy encounters are slower-paced.
The enemies rely on projectiles and contact damage alike to kill the player. Bosses may often appear as regular enemies inside rooms, just like in Sheol.
Forced damage is significantly less common than in Sheol.

The boss of the floor is always Isaac

Floors – Chapter VI

These are all the floors of Chapter VI
These floors are extremely hard without good items.

The first of the two final floors.

Accessed through the Cathedral’s boss room, while having the Polaroid item in your inventory.

The starting room of the floor will always contain four golden chests.
Every chest in the floor (with the exception of Red Chests) will always spawn a random item from the Treasure Room pool.

Beating ??? or the Lamb once will force the Golden Door to always spawn on the northern wall of the spawn room. This door leads to the Mega Satan fight, and can be unlocked with the following items:

• An assembled key from the items: Key Piece 1, Key Piece 2
• Dad’s Key active item
• Sharp Key active item
• Mr. ME! active item
• Cracked Orb passive item
• Get Out of Jail Free consumable

The door also appears in the Dark Room after the conditions have been met for it to spawn.

The enemies inside the Chest are almost always bosses, but rooms with enemies can rarely appear as well.

One thing of note is that doors cannot be bombed open anymore, something not seen in the previous floors/chapters.

The boss of the floor is always ???

The second of the two final floors.

Accessed through the Sheol’s boss room, while having the Negative item in your inventory.

The starting room of the floor will always contain four red chests.
Each red chest in the starting room will spawn an item for sale, priced in heart containers, just like in a Devil Room.
Every chest in the floor (with the exception of Red Chests) will always spawn a random item from the Treasure Room pool.

The enemies inside the Dark Room are almost always bosses, but rooms with enemies can rarely appear as well.

Just like in the Chest, doors cannot be bombed open.

The Dark Room contains a special room, called the Grave Room. It spawns every time, and contains 1-4 disturbed patches of soil. Using the Mom’s Shovel item while standing on top of them will unlock the Forgotten character. Subsequent uses of Mom’s Shovel will unearth chests, which contain items. The We Need To Go Deeper! active item does the same thing, but cannot unlock the Forgotten.

The boss of the floor is always the Lamb.

Floors – Chapter VII (Endgame)

These are the two truly final chapters.

The actual final chapter, unlocked by defeating Hush.

Accessible only through a Void Portal.
These portals have a chance to spawn after defeating a final boss.
The stronger the final boss is, the higher the chance is for the portal to appear.
The individual chances for each final boss are listed below:

* – requires the player to have either 10+ damage or 20+ items.

The floor is enourmous, usually stretching out to the 13×13 floor size limit.
Each room in the floor is a random room from any floor between Chapter I and Chapter VI.
The floor contains multiple boss rooms, and one of them will always contain Delirium.
The non-Delirium boss rooms will have a random boss fight. This includes final bosses (except Mega Satan, Hush, Mother and the Beast)

The room containing Delirium can be figured out by looking at which rooms it neighbors.
Delirium’s boss room is always 2×2, which is not depicted on the map. Using this information it’s possible to deduce its position, by checking if the room meets the conditions to be able to spawn as a 2×2.

Killing Delirium does not immediately end the game and lets the player explore the floor a bit further. Ultimately though, the player has to enter the End Chest dropped by Delirium and finish the run.

The second true final chapter, added in Repentance. Unlocked by defeating Mother.

Home is accessed by ascending back out of the Basement. More on that in Floors – Going Home.

The layout of Home is always the same, just like the Blue Womb.

The right wing contains the starting room, along with a little closet, which can contain a random pickup, or an item in extremely rare cases. The starting room contains a golden chest and a bed. This bed functions normally, just like the ones in Bedrooms.

The left wing contains Mom’s room, and a hidden closet, containing:

• A tainted character, if it has not been unlocked yet for the character you’re playing as
• A shopkeeper, if the tainted character has been unlocked and Inner Child has not.
• The Inner Child item, if the tainted character has been unlocked, and Inner Child itself is unlocked

The hidden closet can only be opened by the following:

• the Red Key active item
• the Cracked Key consumable
• the Soul of Cain consumable

The middle room contains a couch and a TV, both non-interactable.

As for the previously mentioned Mom’s room, the player can find Mom’s bed, Mom’s chest and a few non-interactable pieces of furniture. Mom’s chest will always drop the Red Key the first time it’s opened. Subsequent openings will spawn a random Mom-related item.
Sleeping in Mom’s bed triggers a stage switch, and Home turns dark.

In the dark Home, the only differences are the turned-on TV in the middle room.
Walking in front of it triggers the Dogma boss fight, which in turn triggers the Beast fight sequence.

Floors – Unlocking the Corpse

The fourth repentance chapter, The Corpse, is locked by default, and the player needs to complete a puzzle to unlock it.
The puzzle consists of assembling a special knife, and using it in Mausoleum II to open the Womb door, leading to the Corpse.

The first piece of the knife is located in Downpour II (or Dross II, the version does not matter)
For accessing Downpour, see Floors – Chapter I

To acquire it, the player needs to access the treasure room inside the Mirrorspace.

To access the Mirrorspace, the player needs to kill themself on a white fire, which spawns in a random room on the floor. This will temporarily turn the player into The Lost.

The Lost, Tainted Lost and Tainted Forgotten do not have to touch the white fire, and can go inside the Mirrorspace right away

It is recommended to clear the area between the Treasure Room, the mirror room and the white fire room before attempting the puzzle, to know where you’re going and what you’re going to be up against in the Mirrorspace.

Once the player is turned into The Lost, they need to head to the mirror room, which spawns in a random dead end in the floor. In there, the player needs to walk through the mirror; this will take them into the Mirrorspace.

Inside the Mirrorspace, all rooms contain enemies again, as if you didn’t enter them before. Various special rooms are also completely empty, with the exception of Treasure Rooms and Boss Rooms.
The map information is kept between the realms.

Once inside, the player needs to head to the floor’s treasure room.
The knife piece will be standing on top of a pedestal inside the room.
Once the player has acquired the knife piece, they can head back to the mirror, which will turn them back into their normal character.

The player can additionally exploit the Mirrorspace, by defeating the realm’s boss, as Boss Rooms do not get emptied unlike other special rooms. This lets the player acquire an additional boss item at the cost of having higher risk of death.

The second piece is located in Mines II.
For accessing the Mines, see Floors – Chapter II

To acquire it, the player needs to enter the puzzle room inside the minecart room.

The minecart room always spawns on Mines II, if the player has the first Knife Piece acquired.
This minecart room will host an unfinished rail system, a yellow button, and occasionally a few enemies. There is also a boarded-up door on the northern wall. This door leads to the puzzle room.

The door can be opened in two ways.
The first one involves just bombing the door twice. It behaves like a regular bedroom door. This method requires the player to have flight though, along with two bombs.
The second, inteded method is to press the three yellow switches, scattered across the floor.
One of the switches is always in the minecart room, while the two others are in random 1×1 rooms in the floor.

Once the door has been opened, the player can enter the puzzle room.
The puzzle room always has a pre-defined layout, shown below.

The room tinted red in the picture contains the second piece of the knife.
Picking it up triggers an escape sequence; Mother’s Shadow spawns above the pedestal, and the doors close until the shadow finishes the laughing animation.
After the doors open, the player is tasked with escaping the puzzle room.
The path previously walked by the player will be laid with various obstacles and/or traps, which need to be cleared, all while the Mother’s Shadow is trying to stop the player.

In Mausoleum II, when the player kills Mom, a Womb-esque door appears.
This door needs to be cut open using the assembled knife. Doing so will remove it from the inventory.

In the room, the player will have to fight a stronger version of Mom’s Heart.
After killing the heart, the player will stumble upon the entrance to the Corpse when they walk out of the room.

• The whole process needs to be repeated each time the player wants to access the Corpse.
• The puzzle parts in Downpour II and Mines II can be done at any point in the floor, so the player can spend as much time as possible casing the floor and preparing themselves.
• It is heavily recommended that the player unlocks the Holy Mantle for the Lost, since this transfers to the Lost form in Downpour as well, giving extra survivability
• More than one white fire can spawn. However, all of the additional white fires will be in the same room as the original one
• It’s heavily discouraged to use items that give flight temporarily, such as the Bible, when entering the puzzle room in Mines II, as exiting the puzzle room after entering it will softlock the player with no way out, assuming any of the three switches haven’t been pressed.
• Characters which have flight by default (e.g. Azazel, The Lost, Tainted Lost, Tainted Forgotten) do not have that flight taken away when entering the puzzle room, meaning they can carelessly rush through the obstacles presented during the escape sequence.
• The player can take an “easy route” by entering as little repentance floors as possible. This can be done by normally doing Basement I and II, and entering Downpour II from Basement II, instead of entering Downpour I from Basement I. After acquiring the first knife piece, instead of heading down to the Mines, the player can go to Caves II, and then from there to Mines II to get the second piece. After this, however, the player will still have to go through Mausoleum I regardless. This method gives you less options regarding items, but results in a safer run
  • If you’re going to do this, keep a constant mental note of where you will go after the boss. There’s nothing worse than forgetting to go to Downpour II and going to Caves I instead.

Floors – Going Home

Home is a secret chapter added in the Repentance DLC. This floor hosts 6 boss fights and not much else, sort of similar to the ??? floor.
This is also the floor where the player can unlock a tainted version of their character (more on that in Tainted Characters).

After defeating Mother, a weird, fancy door will always appear in Depths II and its variants (except for Mausoleum/Gehenna II).
This door needs to be unlocked to get to Home.

To open the door, the player needs to unlock it with the Polaroid, or the Negative.
This poses a problem, because under normal circumstances the player cannot acquire the Polaroid, or the Negative, and get back to the spawn room, since the player is permanently locked in once they enter Mom’s boss room.
This lockdown can be bypassed by teleporting yourself out of the boss room.
This can be done in 4 ways, including:

• Any tarot card with a teleport effect (except for the Emperor card for obvious reasons)
• Any active item with a teleport effect
• Taking damage while charging Cursed Eye
• The Telepills pill effect

Fortunately enough, in Depths II, once the Strange Door has been unlocked, a marked skull will always appear in a random room in the floor. (see Environment – Rocks for more info).

Alternatively, the door can be unlocked with the Faded Polaroid trinket; a little nod to how the player used to access the Chest in the original Binding of Isaac.

Behind the door the player will find the trapdoor to Mausoleum II.
In Mausoleum II’s boss room, the player doesn’t fight Mom. Instead, they see Dad’s Note placed on a pedestal in the middle of the room.
Picking it up triggers the ascension sequence,

As the title above says, after picking up the note, the player then starts ascending back through the floors they came from, starting in Mausoleum II and finishing at Basement I.

Unlike what you’d expect, the floors get harder the higher up you are.

• Depths-level floors are usually extremely small, only consisting of up to ten rooms, and contain usual depths-like enemies.
• Caves-level floors are larger than the previous ones, and contain slightly harder enemy layouts.
• From Caves II and onwards the player can encounter tainted enemies; special, and hard-to-kill versions of normal enemies. Their high survivability comes from the fact that they have boss armor, meaning they get a certain amount of damage absorption the more they’re hit. Bombs ignore this mechanic entirely (does not apply for Dr. Fetus; its bombs are considered tears).
• Basement-level floors are just as big as Depths-level floors when not ascending, and contain difficult enemy layouts. Tainted enemies are not a rare sight in the Basement.

Going through the light beam in Basement I takes the player to Home
To read up about Home, navigate to Floors – Chapter VII (Endgame)

Special Rooms – Introduction

Floors in the game are made out of rooms. Some rooms have special properties, and such rooms will be discussed in this section.

Special Rooms #1

A Treasure Room, as the name implies, contains treasure, in the form of items, whether they be passive or active.

They spawn from Basement I all the way up to Depths II.
They can also spawn in the Womb, if the player holds the Bloody Crown trinket.
They can also spawn in Sheol if the player is holding the Wicked Crown trinket.
Only one Treasure Room spawns per floor (in XL floors, two treasure rooms will spawn)

These rooms are locked by default and need a single key to open them, with the exception of the Treasure Room in Basement I, which is always open

A Treasure Room may rarely contain two items, with the player being able to pick up only one of them. These rooms are guaranteed to spawn if the player has the More Options passive item.

“Bulb” enemies may sometimes be encountered in these rooms.

Shops contain items on sale. These items can have a price ranging from 2 to 15 cents.
The price depends on the type of item on sale, as shown in the table.
Items on sale in shops can also be on a discount, halving their price.

Shops, just like Treasure Rooms, require a single key to open, with the exception of the Basement I shop, which is always open.

Shops, just like Treasure Rooms, will appear from Basement I, to Depths II.
They will also appear in the Womb, if the player is holding the Silver Dollar trinket.

A default shop will contain two pickups/consumables on sale.
Each shop contains a Donation Machine, to which the player can donate money.
Donating enough money upgrades the shop for future encounters.
Shops can be upgraded 4 times. Each upgrade level is shown in the table below.

In shops past Caves I, the Greed miniboss can appear inside a Shop, replacing all of the items on sale.
If Greed has been encountered previously, Super Greed will spawn.
If both have been killed by the player previously, they will not be able to spawn in shops anymore.

Shops also have two rare room variants that can spawn.
One of them is a fully upgraded shop, with two lucky pennies and two Keeper enemies,
while the other one has a single item for sale and nothing else.

Boss Rooms are the gatekeepers of pathways to further floors.
There is always one boss room on each floor, with the exceptions being:

• XL floors, featuring two boss rooms
  • The two rooms will be connected to each other
  • The second room’s boss will need to be defeated to be able to progress to the next floor.
• The Void, featuring multiple boss rooms

Killing the floor’s boss rewards the player with the path to the next floor, a Boss Room item, and/or a few hearts, depending on the difficulty.

Sometimes a Devil/Angel room may also appear in the room after defeating the boss.
It’s recommended to not leave the boss room when this happens, as the deal room will often disappear upon reentering.

Boss Rooms may rarely feature a Double Trouble fight, which involves fighting two, weaker bosses at the same time. The reward is the same.
Double Troubles start to have a chance to appear from Caves I.

Some boss rooms may be bigger than a standard 1×1 room. The size of the room is determined by what is the floor’s boss. The following bosses will have a bigger boss room:

Mini-boss rooms are regular rooms, which feature a mini-boss fight.
This fight can feature one regular deadly sin mini-boss, or one super mini-boss.
Ultra Pride can also rarely spawn in these.

Mini-boss rooms appear as normal rooms on the map, unless you have a form of mapping that reveals special icons (these are the Spelunker Hat, Compass, and the Mind passive items)

Active mini-boss rooms prevent the player from bombing the door.
Bombing an adjacent secret room wall will reveal the secret room but not open the door.

Challenge Rooms contain 1-3 chests of any type.
Opening any of the chests spawns three waves of enemies, each one after the previous one was killed.

Challenge Rooms will be open only when the player’s health is equal to, or greater than their amount of red heart containers.

Once any chest has been opened, the player cannot leave the room until they clear all waves.
This can be bypassed by teleporting yourself out of the room.

Only opening chests and picking up pedestal items triggers the room. Picking up pickups does not.

Special Rooms #2

Boss Challenge Rooms function identically to normal Challenge Rooms, except they always have an item from the Boss Room pool instead of chests, and, as the name suggests, the room spawns bosses of the current floor instead of enemies.

The conditions for the room to open are different as well, requiring the player to have one, or less hearts to enter the room.

Curse Rooms most of the time contain red chests, but can also rarely contain items, or just enemies and nothing else.

Entering a Curse Room has a price, and the price is health. The door hurts the player for half a heart (for a full one in the Womb and beyond).

This damage can be partially bypassed if the player has flight; entering the room does not damage the player, but exiting, does.

The damage can also be bypassed entirely if the player has a reliable source of invincibility, such as Tooth and Nail, Breath of Life, or the i-frames from Ventricle Razor

Sacrifice Rooms are rooms, where the player can exchange large amounts of health for various goods.

The player can sacrifice their health on the spikes in the middle of the room.
The spikes bypass flight, and damage the player for a full heart.

The room’s rewards are always pre-determined, but only have a chance to occur upon each sacrifice.
The rewards are the following:

* – 1 bomb (100%), if the player has defeated the floor’s boss in under a minute and has no bombs.
** – Replaces the Devil Room with an Angel Room if the effect occured on a Chapter 1 XL floor.

Arcades contain various gambling machines and/or beggars.
Arcades are locked by default, and need to be unlocked via entering a single penny in the door slot.

They have a chance to spawn only if the player has 5+ coins on them when they enter the floor.

Libraries are rooms that contain book-related items.
They are locked by default, and need a key to be opened.

Libraries can also rarely contain consumables, and may very rarely contain enemies.

Libraries take their items from the Library item pool. This pool is one of the, if not the smallest in the game, meaning it can easily be exhausted, with items like the D6.
After the pool is exhausted, Libraries will start spawning Treasure Room items.

Planetariums are rare rooms, which contain items from the Planetarium item pool.
They are locked by default, and need a key to be opened.

Planetariums by default have a 1% chance of spawning on a floor.
This chance can be increased by the following:

Bedrooms are special rooms, where the player can recover their health.
They are locked by default and need two bombs to be opened.

A bedroom will always contain a bed. Sleeping in the bed heals any empty red heart containers.
If the player has no red heart containers, the bed will grant three soul hearts instead.
The player can sleep in the bed only once per floor.

There are two types of bedrooms, clean ones and dirty ones.
The only difference between the two, is that a clean bedroom will have the carpet spawn a Crawl Space when it’s bombed, while the dirty bedroom will spawn the trapdoor to the next floor instead.

Special Rooms #3

Vaults are rooms, where the player can usually find chests with various loot.
Vaults are locked by default and need two keys to be opened.

Make sure to have a handful of keys on you, as the two required to open the door are usually not enough, considering the Vault itself often contains keyblocks and/or golden chests.

Dice Rooms are rooms where the player can cast an effect, which affects the floor.
This can be done via the dotted mat in the center of the room.
Pickups and/or consumables may also rarely spawn in the room.
Dice Rooms are locked by default and need two keys to be opened, just like Vaults.

The effect of the room is determined by the amount of pips on the mat.
There are six different effects, including:

Secret Rooms are rooms that are not visible on the map under normal circumstances, and need to be bombed into to access them.

These rooms often contain a handful of pickups, but can contain items in rare cases.
They also almost always contain at least one Shopkeeper.
(Super) Greed may also sometimes spawn in the room.

Secret Rooms often spawn next to 2-4 normal rooms. These rooms cannot have any obstacles, which would otherwise obstruct a doorway leading to the Secret Room.
There can be only one secret room per floor.

Super Secret Rooms are secret rooms, which are adjacent to only one room.
They are accessed the same way normal Secret Rooms are.
There can be only one super secret room per floor.

The rewards inside Super Secret Rooms are usually worse than what you’d find in a normal secret room, since they’re mostly situational.

A Super Secret Room can have various rewards depending on its background.

Ultra Secret Rooms are the red room variant of Secret Rooms.
Each Ultra Secret Room contains a random item from the Angel Room item pool.
There can be only one ultra secret room per floor.

Ultra Secret Rooms generate adjacent to at least two red rooms, which are themself adjacent to any normal room (one of the red rooms needs to be adjacent to a special non-red room).
The red rooms can only be accessed by:

• The Red Key active item
• The Cracked Key consumable
• The Soul of Cain consuamble
• The Crystal Key trinket

Upon entering a red room that is adjacent to the Ultra Secret Room, the secret room will be automatically opened and the secret room jingle will play.

The player can also teleport directly into the Ultra Secret Room via the reversed XVIII – The Moon tarot card

Crawl Spaces are special, Treasure-Room-like areas, which are hidden somewhere in the floor by default, and need to be revealed to be entered.

A Crawl Space entrance will look like a trapdoor to the next floor, with an additional ladder leading downwards.

This entrance can be uncovered, or spawned by the following methods:

The inside of a Crawl Space has different physics than normal rooms.
This is because Crawl Spaces are viewed from the side, instead of how rooms are usually viewed; from the top.
This in turn causes the player to be affected by gravity, if they’re not on top of a ladder.

A Crawl Space may also rarely not feature any items or pickups at all, but an entrance to a Black Market. This entrance also has a chance to bring you to the I AM ERROR room.

Black Markets are special, Devil-Room-like 2×1 rooms, which are accessed via Crawl Spaces.

In the Black Market, the player will find a trapdoor to the next floor, along with a couple items on sale for heart containers. Taking the deal will not decrease Angel Room chance.
The player may also find a few pickups, beggars or machines alongside the items.

On the western wall there will be a door leading back into the crawl space.

Special Rooms #4

I AM ERROR rooms are special rooms, which are not connected to any rooms on the floor.
They can only be accessed via means of teleportation, or by glitching out of a Crawl Space.

These rooms will usually contain a few items, or consumables, but they will always contain a trapdoor to the next floor.

There is no way to escape the room other than the trapdoor, unless the player has a way to teleport themselves out of the room.

The I AM ERROR room can be accessed via the following methods:

* – includes the floor’s Deal Room
** – consumes both the Blank Card and the ? Card

Red Rooms are inaccessible rooms that are hidden from the player.
They can be accessed via the Red Key active item, or the Cracked Key/Soul of Cain consumables.

Red Rooms behave identically to normal, non-special rooms, with the exception of the walls of the room being tinted red, and the soundtrack having its pitch shifted slightly every few seconds.

Generated Red Rooms have a 10% chance to be a special Red Room, e.g. a Treasure Room, Angel Room, etc. (Such red rooms can never be mini-boss/boss rooms). There is no limit to how many special Red Rooms can generate on a floor.

The general purpose of Red Rooms is to allow the player get more pickups/items.

In Chapter V and below, creating a red room past the 13×13 boundaries of the floor will create a door, which will lead the player to an I AM ERROR room.

The player can see such doors being created if they look at the map when they create the door;
if no adjacent cell is revealed upon unlocking a new red room, the doorway will lead the player to an I AM ERROR room.

Deal Rooms

Deal Rooms are special rooms, which may appear after defeating a boss, and contain items that are free (Angel Room), or on a sale (Devil Room)

There are two Deal Room types; the Devil Room and the Angel Room

Devil Rooms
Devil Rooms are deal rooms, where the player can trade their heart containers for items.

Low-tier items usually cost one red heart container, while high-tier items cost two.
If the player doesn’t have enough/any heart containers, they can pay with soul hearts instead.

If the player doesn’t have enough health to make the trade, picking up an unavailable item will kill them immediately. If the player had extra lives prior to their death, they will respawn and get to keep the item they took.

Sometimes black hearts may spawn alongside the trades.
Sometimes a row of three red chests can replace the trades instead.

Trading with the devil eliminates the chance of Angel Rooms spawning.

Not entering the first DeviI Room the player sees guarantees a 100% chance for the deal room to be an Angel Room the next time they encounter a deal room spawn.

Krampus may sometimes spawn and replace the trades.

Angel Rooms
Angel Rooms are deal rooms, where the player gets rewarded with an item, which they can take for free.

Taking an item from the Angel Room does not eliminate the chance of a Devil Room spawning instead.

Sometimes the free item may be accompanied by pickups, such as eternal hearts or soul hearts.

Sometimes the player may have to choose between two to four items; taking an item causes all others to despawn.
The items may very rarely be locked behind a keylock.

Spawn rules:
Deal Rooms are not guaranteed to spawn after a boss fight, and the chances of the deal room spawning are decreased if:

• The player took damage to their red hearts
  If they did, the Deal Room chance decreases by 66% if they were hit in a normal room, or by more than 90% if they were hit in the Boss Room.

• A Deal Room door was seen less than two floors ago
  If a Deal Room door was seen two floors ago, the chance for another one to spawn decreases to 66%. If the door was seen one floor ago, the chance decreases to 33%

Angel Room spawn rules:
Angel Rooms have one more spawning rule.

• The player didn’t trade off their hearts
  If they did, the Angel Room chance drops to 0% and stays like that until the end of the run, unless they pick up items which prevent that from happening, or revert it.

Modifying the spawn chance:
The spawn chance of a Deal Room can be modified by doing certain things.
These actions are listed below:

Multipliers stack additively
Most of these modifiers affect the current floor only

Curses

Throughout a run, you can get a random curse which lasts for the entire floor. While the chance of getting a curse is not established (based on available information), the chance of getting a curse is small in normal mode, yet much higher in hard mode.

When the floor has a curse, a small, purple icon will appear under the map (Repentance only)

Below is a table describing each of the six curses.
(There is also a seventh curse; the Curse of the Cursed, which turns every door into a spiked door. However, this curse only appears in a single challenge and will not be listed)

The Map

• The room that you’re currently in is white
• The rooms that you’ve cleared are light gray
• The rooms that you haven’t cleared are gray
• Without certain items you can only see rooms adjacent to the rooms you’ve been in
• Pickups are marked on individual tiles on the map
• Machines are marked with their respective symbols on the map
• A golden star on a tile means that there is an item in that room
• A silver star on a tile means that there is a trinket in that room
• A white questions mark signifies a secret room
• A gray question mark signifies a super secret room
• A red question mark signifies an ultra secret room
• Various symbols indicate special rooms, navigate to Special Rooms to check them all out

Parts of the map can be shown by certain items such as:

• The Compass – Reveals special room icons
• Treasure Map – Reveals tiles
• Blue Map – Reveals secret rooms
• The Mind – Reveals everything

These items, if acquired, will appear under the map as a small icon, as pictured below.

Victory Laps

Victory Laps are very similiar to loops in Nuclear Throne. Upon killing The Lamb you get a message, which asks you if you want to start a victory lap or not. Choosing “NO” will end the game normally. Choosing “YES” will spawn you in Basement 1 with all of your items.

Beginning a Victory Lap adds difficulty to the game.

In a Victory Lap:

• The player takes a full heart of damage
• Completion Marks and Achievements cannot be earned, except for achievements specifically tied to Victory Laps
• The game automatically switches to hard mode

After a third lap, the player becomes The Lost, and shops are gone.
Killing a final boss other than The Lamb will end the Victory Lap streak

Modes – Introduction

The game can be played in four difficulty modes; Normal, Hard, Greed and Greedier (the last two need to be unlocked first)

This section will be going over the Hard mode, Greed mode, and Greedier mode.

Modes – Hardmode

As the name suggests, hardmode is a harder version of the game.

The differences between normal and hard are:

• 2-3 more rooms generate per floor
• Easy rooms have a lower chance of appearing
• Enemies have a base chance of 20% of becoming a Champion, instead of the normal mode’s 5%
• The shot speed and movement speed of some enemies is increased
• Hearts are 33% less likely to drop upon a room clear
• Curses are more common
• Blood Donation Machines and the IV Bag item give out only one coin per use
• Devil Beggars and normal Beggars require at least six donations to pay out
• Shops with lower upgrade levels can appear
• Blue (and Purple) Fires drop soul hearts 10% of the time instead of the normal mode’s 25%
• The Dogma item does not provide the Wafer effect

Filling every non-tainted character’s sticky note with completion marks on hard mode unlocks the Mega Mush item.

Filling every character’s sticky note with completion marks on hard mode unlocks the Death Certificate item.

Modes – Greed(ier)

Greed Mode is a mode completely different from the game. Its more arcadeish, features different floor progression with two new floors entirely, and a unique final boss.

All floors in Greed Mode are laid out like in the picture above, with the exception of The Shop, which lacks the treasure rooms, and Ultra Greed, which has a completely different layout.

The main, 1×2 room is the arena, where the player fights enemies and earns money.
The two rooms to its side are the Treasure Rooms, as indicated by the icons on the map.
The room to the left is the Curse Room, where the player can risk their health in exchange for various rewards
The room to the north is the Shop, where the player may buy a few items to aid them in their run, and the room to the south is the exit to the next floor, which is unlocked only when all waves have been cleared.

Greed Mode has different floor progression, which includes two new floors.
The progression goes like so:

Just like in normal/hard mode, the first 4 chapters of Greed Mode have an alternate version of themselves. There aren’t any massive difficulty spikes between them though.

One thing to note is that the player takes half a heart of damage in all floors, unlike in normal/hard mode, where the player starts taking full heart damage in Chapter IV and beyond.

To progress through the floors, the player has to go through ten (11 in Greedier) waves of enemies, the last two of which are boss waves.

When a wave spawns, a corresponding amount of coins is spawned in the top half of the room.
These coins can never be anything other than pennies, and how many will spawn depends on the wave:

After all waves have been cleared, including the boss waves, the button used to spawn the waves will have a pentagram symbol on it. Pressing the button will spawn a harder boss wave, which upon completion spawns the entrance to the floor’s Deal Room in the bottom left corner of the room.

Unlike in the normal game, the Deal Room is guaranteed to spawn once its corresponding wave has been dealt with.

The Deal Room wave does not spawn any coins and is not necessary to complete to progress to the next floor.

The waves can be spawned in by stepping on the button in the middle of the room.
Once pressed, the timer below the button will begin ticking down, indicating when the next wave will spawn. If all enemies in the room are killed before the timer reaches 0, it automatically spawns the next wave immediately, regardless of how much time was left.

The button can be pressed again to stop the game from spawning waves, at the cost of half a heart, indicated by the spikes that sprout out of the button.

The amount of time left before more enemies spawn depends on the current wave and floor.
Generally, stronger waves and early-game floors will give you more time before more enemies spawn, while weaker waves and end-game floors will give you less time.
Boss waves always set the timer to 30 seconds.

The game will not spawn bosses after all enemy waves have been cleared, and the player will need to press the button again to do so.

The first new floor the mode introduces is the Shop, which is basically the equivalent of Chapter VI in the normal game. In this floor, the enemies are very complex, sometimes tanky, and spawn in extremely large amounts. Bosses aren’t a rare sight either. The Deal Room wave of this floor usually includes tons of enemy spam, and almost always contains the Stain, for some reason.

The second new floor is Ultra Greed. This floor is the final floor of the mode, and hosts its final boss, Ultra Greed.
The floor consists of three rooms; the spawn room, the mini-boss room, and the final boss room.

The mini-boss room appears empty at first, but once the player walks in the middle, a random assortment of minibosses spawn. This miniboss needs to be killed to proceed to the next room.

The final boss room contains Ultra Greed. Killing him finishes the run, spawning an End Chest and a Greed Donation Machine. (Ultra Greed will transform into Ultra Greedier upon death, if you’re playing on Greedier Mode)

FInishing the run spawns a Greed Donation Machine alongside the End Chest. This machine can be donated to, and doing so can unlock special features, which affect both the normal game, and Greed Mode itself. The rewards, and the amount of coins that needs to be donated to attain them are listed in the table below.

The machine can also jam, just like regular Donation Machines.
The chance is dynamic, and dependent on the character youre currently playing as.
The more coins you donate with a specific character, the higher the jam chance is for that character.
Upon killing Ultra Greed, the jam chance appears on the left side of the HUD.

Greedier is what Hard mode is to Normal mode; a harder version of its predecessor.
It’s locked by default, and the player needs to donate 500 coins to the Greed Donation Machine to unlock it.
The differences between Greedier and Greed are:

• An additional enemy wave is added, bringing the total to 11 (12) waves (9 enemy, 2 boss, (1 deal room))
• The time between waves is significantly shorter from the Depths and beyond (this includes boss waves)
• Enemies have a chance of becoming champions, and do not drop champion rewards
• The waves give less coins overall
• Ultra Greed gains a second phase (see Final Bosses – Ultra Greedier
• The Greed Donation Machine jam chance is significantly reduced

Machines and Beggars

Gambling machines and beggars may sometimes appear during a run. The player can use them to exchange money for possible goods.
In total, there are 8 types of machines, and 8 types of beggars in the game.

Machines

Beggars

Entity Effects

Entity effects are effects, which, as the name suggests, affect entities over time. They can be divided into two sections; status effects and tear properties.

Status Effects
Status effects affect enemies, usually in detrimental ways. There are 13 different status effects an enemy can have, these are:

Tear Properties
The tears the player fires can have different properties, of which there are three: piercing, spectral and homing

Items – Introduction

Items are the biggest part of each of your runs, and the game in general. You need them to survive, and to progress through the challenges the game presents.

The Binding Of Isaac: Rebirth, with its all 3 expansions has 700+ items.
This section aims to list each and every single item, explain their effects and give a few notes or tips on the way.

Items can be divided into two types; passive, and active items.

Passive items are items, which apply their effects to the player constantly, such as stat-ups, probabilities of firing a special tear, etc.

Active items are items, which have their own special slot in the top-left corner of the screen.
The player can only hold one active item at a time under normal circumstances.
Active items can be activated by pressing the spacebar, and they have various effects, such as spawning pickups, dealing damage to enemies, spawning various entities, giving passive effects for the duration of the room, and more.
Active items have a charge to them (most, at least), and can be only used when they’re at full charge.
They can be recharged by clearing rooms, picking up batteries, or picking up items which charge active items.
A few active items can also be used only once, and will be consumed upon doing so.

Passive items also have a subdivision called familiars.
Familiars are entities, which are friendly to the player, and will aid them in their run.
They will usually be dragged behind the player, but there are exceptions.

Familiars themselves also have a subdivision, called orbitals.
Orbitals, as the name suggests, will orbit the player, usually doing contact damage, and blocking enemy projectiles.

There are also temporary familiars in the form of blue flies and spiders.
Blue flies will orbit the player, and attack nearby enemies, dealing 2x the player’s damage to them, while blue spiders will crawl around the room randomly, locking in on nearby enemies, and dealing 2.5x the player’s damage to them. Multiple passive, and active items are able to spawn blue flies and spiders.

This section will put passive and active items in separate groups, and will have them ordered by their internal ID,
(I’m doing this because the internal files of the game also sort them by internal ID, meaning that if I wanted to sort them another way, I’d have to rename all 700+ items manually, which I will NOT be doing)
regardless of any other property, such as their name, or item pool.

There is also such a thing as an Item Pool. These pools are assigned to special rooms, which can drop items, and they dictate what items can be spawned by that room.

Each individual item can be seen only once per run; once you encounter an item, you won’t encounter it in the run again. This means that item pools can get emptied (or “exhausted”). In such case, they will start spawning items from the Treasure Room item pool, and when that one runs out, the game will keep spawning the Breakfast item.

Fixed item drops from enemies like the Deadly Sins overwrite the item pool rules, meaning that if you, for example, find the Virus item in a Treasure Room, and then fight Lust, Lust will still be able to drop the Virus, giving you a chance to have a copy of the item.

The Greed game mode has a completely different set of item pools from the base game.

There are 22 individual item pools in the game, and 9 Greed Mode item pools, but for the sake of my sanity, Greed Mode pools will not be mentioned in the item properties, only the normal mode pools.

To allow for easier searching, item pools will not be described as e.g. “Treasure Room”, but “pool_treasureroom” in the tables, to avoid the search tool mixing up results from the actual items section, and non-items sections, which just happened to mention that specific item pool in normal wording.

All of such tags and their explanations are listed in the table below

Use these tags to search for specific item pools

Passive Items #1

These are all of the passive items in the game, sorted by internal ID.

Passive Items #2

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Passive Items #46

Active Items #1

This is a list of all active items, sorted by internal ID

Active Items #2

Active Items #3

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Active Items #14

Active Items #15

Active Items #16

Active Items #17

Special Items #1

These are special items; items, which are essential to progression in the endgame, cannot be rerolled, and spawn from specific events.
They’re all listed below and sorted by their internal ID

Special Items #2

Trinkets – Introduction

Trinkets are useful little things that help you throughout your run.
They have their own slot in the bottom left corner, and under normal circumstances the player can hold only one trinket at a time.
Trinkets can drops from various sources, including room clears, chests, or even some items.

Most of the trinkets provide small boosts/effects as long as the player keeps hold of them.
If the player does not want to hold a certain trinket, they can stand still and hold LEFT CTRL, to drop their trinket, along with their current consumable.

After defeating Mega Satan with Tainted Jacob, trinkets will have a small chance to appear as their golden version. Golden trinkets have double the effect they would have normally, however, some trinkets don’t benefit from being golden at all.

The game with all of its DLC installed contains 188 trinkets.
All of them, just like the items, will be sorted by their internal ID.

Disclaimer: I will not put the effects of golden versions in the table, as doing so would mean I’d have to spend at least 5 minutes on each trinket, and I don’t have that kind of time, nor commitment.
For a golden trinket, just imagine you’re holding two instances of the same trinket, and that should give you the rough idea of how the golden version will work.

Trinkets #1

Trinkets #2

Trinkets #3

Trinkets #4

Trinkets #5

Trinkets #6

Trinkets #7

Trinkets #8

Trinkets #9

Trinkets #10

Trinkets #11

Trinkets #12

Trinkets #13

Transformations – Introduction

Picking up items with a certain theme to them can transform the player.
This gives them a unique costume and a special ability which comes with the transformation.
There are 15 transformations in the game, with all of its DLC installed.
Their properties and requirements are listed below

Transformations #1

Transformations will be sorted alphabetically, while the required items will be sorted by internal ID, and active items will be listed before passive items, regardless of ID

A transformation always requires the player to pick up three items of a certain theme; not encounter, nor anything else. Active items contributing to a transformation can be dropped safely; they are recorded for the rest of the run. I’ll avoid putting this bit in the “required items” section to avoid needless clutter

Transformations #2

Enemies – Introduction

Enemies are your main and biggest obstacle in TBoI: Rebirth. Their difficulty varies with floor, with some enemies not even being able to damage you, while others being able to end your run in mere seconds.

Enemies in this section will be grouped into categories, and the categories will be sorted by the complexity of enemies they contain. The same will mostly apply to enemies themselves, although visual similarity will also be a factor.

For the sake of my sanity, this guide will not specify where enemies can be encountered, or how much HP they have, just their behavior

Turrets are considered as enemies by the game, but I won’t put them in this section, as this has already been done in Environment – Turrets

All enemies deal contact damage to the player, unless otherwise specified.

Enemies can also appear as champions. What they are and how they work is described in the section below, along with entity armor and stage HP.

Enemies – Champions

Champions are stronger versions of enemies, which boast higher health pools and/or special abilities.
They appear more often in Hard mode than in Normal mode, and are indicated by having a tint, or a special animation.
Champions will also sometimes drop pickups upon death.
There are 25 different champion types in the game. They will be sorted by their internal ID.

Enemies – Entity Armor, Stage HP, and Boss Enemies

Armor is a mechanic mostly found on bosses and final bosses, however some of the more lategame enemies also have this mechanic, hence why this section is grouped with Enemies rather than Bosses.

To put it short, entity armor is a feature introduced in Afterbirth to provide extra challenge while fighting enemies.
This mechanic enables some enemies and bosses to retaliate against high damage attacks by reducing how much damage they take from them.
The formula which decides this is fairly complicated but all you need to know is that the more you attack an armored enemy in a short period of time, the less damage you’ll be doing.
This video is a really good showcase of this mechanic.[a.pomf.cat]

Armor is a value in the game’s code. The higher it is, the more effective the damage scaling is.
Below is a table showing the armor values of all enemies and bosses which possess entity armor.

For reference:

• 0-5 armor is barely noticeable
• 10-15 armor is noticeable on enemies, not so much on bosses
• 15-30 armor is highly noticeable on enemies and slightly noticeable on bosses
• 30+ armor poses a challenge, regardless of the enemy type
• 100+ armor extends a 1 minute boss fight into a 10 minute one.

Enemies

Bosses

* – Delirium’s armor increases depending on damage taken while in minion form. His true form always has no armor

Stage HP is a mechanic sort of similar to entity armor, albeit a bit fairer.

Stage HP is a value, which gets added to the HP of an enemy with each floor you descent.

In Layman’s terms, a Dip with 3 HP in Basement 1 will have 4 HP on Basement 2, since their stage HP value is 1. This essentially means that a Dip gets an additional 1 HP per floor.

This mechanic is the most noticeable specifically on Dips, as in Basement 1, a single base damage shot can kill them, while on Basement 2, you’ll need two shots to kill a Dip.

Boss Enemies are a subdivision of enemies, which are powerful and/or complex enough to be considered a boss by the game.
Enemies considered as bosses by the game will be very resistant to status effects, and will usually display a boss health bar on screen when encountered.

Enemies – Flies #1

These are the enemies, which resemble flies.

Enemies – Flies #2

Enemies – Flies #3

Enemies – Spiders #1

These are enemies, which resemble spiders

Enemies – Spiders #2

Enemies – Wall Creeps

These are enemies, which resemble spiders, but crawl on the walls of the room.

Enemies – Poops

These are enemies, which resemble poop

Enemies – Worms

These are enemies, which resemble worms

Enemies – Maggots

These are enemies, which resemble maggots

Enemies – Hoppers

These are enemies, which resemble the Hopper enemy, or behave similarly to it.

Enemies – Pacers

These are enemies, which resemble the Pacer enemy, or behave similarly to it.

Enemies – Maws

These are enemies, which resemble severed, floating heads, often called Maws.

Enemies – Gapers

These are enemies, which resemble the Gaper enemy, or behave similarly to it.

Enemies – Fatties

These are enemies, which resemble the Fatty enemy, or behave similarly to them

Enemies – Skinnies

The Skinny enemy and its variants

Enemies – Mulligans

These are enemies, which resemble the Mulligan enemy, or behave similarly to it.

Enemies – Clotties

These are enemies, which resemble the Clotty enemy, or behave similarly to it

Enemies – Gyros

The Gyro enemy and its grilled variant

Enemies – Globins

These are enemies, which resemble the Globin enemy, or behave similarly to it

Enemies – Knights

These are enemies, which resemble the Knight enemy, or behave similarly to it

Enemies – Hosts

These are enemies, which resemble the Host enemy, or behave similarly to it

Enemies – Vises

These are enemies, which resemble the Vis enemy, or behave similarly to it.

Enemies – Boils

These are enemies, which resemble the Boil enemy, or behave similarly to it

Enemies – Shopkeepers

These are enemies, which resemble the Shopkeeper environmental object

Enemies – Gurgles

These are enemies, which resemble the Gurgle enemy, or behave similarly to it.

Enemies – Moles

The Mole enemy and its tainted variant

Enemies – Buttlickers

The Buttlicker enemy and its Dank Depths variant

Enemies – Bats

The One Tooth and Fat Bat enemies

Enemies – Ghosts

These are enemies, which resemble ghosts

Enemies – Bonies

These are enemies, which resemble the Bony enemy, or behave similarly to it

Enemies – Death’s Heads

These are enemies, which resemble the Death’s Head enemy, or behave similarly to it

Enemies – Whippers

These are enemies, which resemble the Whipper enemy, or behave similarly to it

Enemies – Goats

The Goat enemy and its variant

Enemies – Cultists

The Cultist enemy and its variant

Enemies – Mom’s Hands

The Mom’s Hand enemy and its variant

Enemies – Masks and Hearts

The Mask + Heart enemy and its variant

Enemies – Balls

The Dark Ball enemy and its variant

Enemies – Oobs

The Oob enemy and its variant

Enemies – Brains

These are enemies, which resemble brains

Enemies – Guts

These are enemies, which resemble guts/intestines

Enemies – Eyes

These are enemies, which resemble eyes

Enemies – Babies

These are enemies, which resemble the Baby enemy, or behave similarly to them

Enemies – Nerve Endings

The Nerve Ending enemy and its variant

Enemies – Tumors

The Tumor enemy and its variants

Enemies – Lumps

The Lump enemy, and the Tar Boy, which functions similarly

Enemies – Leeches

These are enemies, which resemble leeches

Enemies – Doples

The Dople enemy and its variant

Enemies – Demons

These are enemies, which resemble demons

Enemies – Hush

These are enemies, which are visually themed after Hush

Enemies – Coins

Coin enemies spawned by Ultra Greed in Greed Mode.

Enemies – Portals

These are enemies, which resemble portals

Enemies – Other #1

These are enemies, which could not be categorized

Enemies – Other #2

Mini-Bosses – Introduction

Mini-Bosses are monsters that are way stronger than normal monsters, but are too weak to be considered as a boss.

Even then, mini-bosses are still considered boss enemies, and fall under the effects which this category provides

In TBoI: Rebirth there is a total of 18 mini-bosses
All of the mini-bosses are listed down below

Mini-Bosses – The Deadly Sins

This section hosts information for the following bosses:

• Envy
• Gluttony
• Wrath
• Pride
• Lust
• Greed
• Sloth

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Appears in:

• Mini-boss room (Boss)
• Chapter IV, Cathedral (Enemy)

HP: ~100 in total. Exact HP values unknown
Stage HP: 7.5

Behavior:

• Behavior
  Floats diagonally. Upon death, splits into two large heads. Each large head splits into two medium heads. Each medium head splits into two small heads. Small heads do not split and die normally instead. The speed of a head depends on it size; the smaller it is, the faster it floats

• Death
  Envy upon death drops a troll bomb, or, rarely, the Shoop da Whoop item

Tips for the fight:

• Focus on one large head at once

Appears in:

• Mini-boss room (Boss)
• Chapter III, Corpse, Sheol, Cathedral, The Chest, Dark Room (Enemy)

HP: 60
Stage HP: 20

Attacks & Behavior:

• Behavior
  Walks randomly around the room and performs 2 attacks

• Radial Burst
  Occasionally fires out 8 very fast projectiles in all directions

• Brimstone
  If the player is adjacent cardinally to Gluttony, they can charge up and release a brimstone laser shortly after.

• Death
  Gluttony upon death can drop a few Red Heart pickups or the <3 item

Tips for the fight:

• Try to bait Gluttony into using its Brimstone laser; this gives you a decent attack window

Appears in:

• Mini-boss room (Boss)
• Chapter III, Sheol, Cathedral, The Chest, Dark Room (Enemy)

HP: 60
Stage HP: 24

Behavior:

• Behavior
  Walks around erratically and occasionally lobs a bomb towards the player. Wrath tries to run away from their own bombs, but not the player’s

• Death
  Wrath upon death can either drop a few bombs or the Mr. Boom item

Tips for the fight:

• Sometimes Wrath may get stuck on their own bombs.
• If you wanna bomb Wrath instead of fighting them, a good time to put a bomb is when Wrath is walking through a hallway. Putting the bomb in their path usually doesn’t give them the chance to run away

Appears in:

• Mini-boss room (Boss)
• Cathedral (Enemy)

HP: 60
Stage HP: 20

Attacks & Behavior:

• Behavior
  Walks around erratically and performs 2 attacks

• Lasers
  Fires 4 lasers in diagonal directions

• Troll Bombs
  Spawns 4 troll bombs in random places in the room. Pride is immune to their bombs

• Death
  Pride upon death can drop a key, or the Anarchist Cookbook item

Tips for the fight:

• Stay cardinal to Pride, never diagonal
• Try to separate the troll bombs, so they don’t knock each other unexpectedly

Appears in:

• Mini-boss room (Boss)
• Chapter III, Sheol, The Chest, Dark Room (Enemy)

HP: 60
Stage HP: 20

Behavior:

• Behavior
  Chases the player, leaving creep behind themself. Accelerates overtime.

• Death
  Lust upon death drops a pill, or the Virus item

Tips for the fight:

• High speed and/or fire rate help a lot in this fight
• Try to go through a lot of corners in order to slow down Lust

Appears in:

• Mini-boss room (Boss)
• Randomly found in Shops in Caves II and beyond (Boss)
• Sheol, Cathedral, The Chest, Dark Room

HP: 60
Stage HP: 20

Attacks & Behavior:

• Behavior
  Walks around randomly and performs 2 attacks. Greed’s projectile attacks and contact damage from them make the player drop coins (this also deducts coins from their coin count)

• Triple Shot
  Fires a triple shot in the closest cardinal direction to the player

• Spawn Hopper
  Spawns 2 Hoppers.

• Death
  Greed upon death drops either lots of pennies, or, rarely, the Steam Sale item

Tips for the fight:

• Try to put some distance between you and Greed; this gives you the ability to dodge Triple Shot with minimal movement, as you only need to weave in between the shots instead of going around the whole spread
• Alternatively, you can circle Greed at high speeds to avoid getting hit by the Triple Shot

Appears in:

• Mini-boss room (Boss)
• Chapter III, Corpse, Cathedral, Sheol, The Chest, Dark Room (Enemy)

HP: 60
Stage HP: 20

Attacks & Behavior:

• Behavior
  Walks around randomly and performs 2 attacks

• Spawn Charger
  Spawns a charger.

• Ipecac
  Fires an Ipecac-like projectile towards the player

Tips for the fight:

• Focus on the chargers if there are more than two of them

Mini-Bosses – The Super Deadly Sins

This section hosts information for the following bosses:

• Super Envy
• Super Gluttony
• Super Wrath
• Super Pride
• Super Lust
• Super Greed
• Super Sloth

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Appears in:

• Mini-boss room (Boss)
• Cathedral, The Chest, Dark Room (Enemy)

HP: 60
Stage HP: 7.5

Behavior:

• Behavior
  Floats diagonally. Splits into three large heads upon death. Large heads split into 2-3 medium heads. Medium heads split into two small heads. Small heads do not split and die normally

• Death
  Super Envy upon death drops a troll bomb, or, rarely, the Forever Alone item

Tips for the fight:

• Focus on one large head at a time

Appears in:

• Mini-boss room (Boss)
• Corpse, Cathedral, The Chest, Dark Room (Enemy)

HP: 60
Stage HP: 25

Attacks & Behavior:

• Behavior
  Walks around aimlessly and performs 2 attacks

• Brimstone
  If the player is adjacent cardinally to Super Gluttony, they can charge up and release a brimstone laser in front of them and also behind them shortly after.

• Upgraded Radial Burst
  Fires 8 projectiles in all directions along with a small Monstro-like spray of projectiles aimed towards the player

• Death
  Upon death Super Gluttony drops either a few red hearts or the Bucket of Lard item

Tips for the fight:

• Try to bait Super Gluttony into using its Brimstone Laser; this gives you a decent attack window

Appears in:

• Mini-boss room (Boss)
• Cathedral, Sheol, The Chest, Dark Room (Enemy)

HP: 60
Stage HP: 30

Behavior:

• Behavior
  Walks around erratically and occasionally spawns a Super Troll Bomb

• Death
  Upon death Super Wrath drops a few bombs or the Mr. Mega item

Tips for the fight:

• You can use your tears to knock the troll bombs back a bit if they’re too close

Appears in:

• Mini-boss room (Boss)
• The Chest, Dark Room (Enemy)

HP: 60
Stage HP: 25

Attacks & Behavior:

• Behavior
  Walks aimlessly and performs 2 attacks

• Upgraded Lasers
  Fires 4 lasers diagonally and additionally shoots a 6-shot in a hexagonal pattern in a random orientation

• Super Troll Bombs
  Spawns 2 Super Troll Bombs

• Death
  Upon death Super Pride drops either a tarot card or the Dead Cat item

Tips for the fight:

• For obvious reasons stay cardinal to Super Pride, never diagonal
• You can use your tears to knock the troll bombs back a bit if they’re too close

Appears in:

• Mini-boss room (Boss)
• The Chest, Dark Room (Enemy)

HP: 60
Stage HP: 25

Behavior:

• Behavior
  Chases the player, while leaving behind creep. Accelerates over time.

• Death
  Upon death Super Lust either drops a pill or the Yum Heart item

Tips for the fight:

• Flight, or the Callus trinket are good things to have when fighting this boss
• High tear rate and/or speed help a lot in this fight.

Appears in:

• Mini-boss room (Boss)
• Any shop after Caves II and after encountering normal Greed (Boss)
• Chapter III (extremely rare), Cathedral, Sheol, The Chest, Dark Room (Enemy)

HP: 60
Stage HP: 25

Attacks & Behavior:

• Behavior
  Walks around erratically and performs 2 attacks. Any of Super Greed’s projectile attacks or contact damage from them make the player drop a few coins (this also deducts coins from the player’s coin count)

• Spawn Keeper
  Spawns two Keeper enemies

• Quad Shot
  Fires a quad shot towards the player

• Death
  Upon death Super Greed either drops a ton of coins or the Quarter item

Tips for the fight:

• Heavily prioritise killing the Keepers over damaging Super Greed
• Because of how quad shot works, you can dodge it entirely by just not moving, and weaving in between the center projectiles. Because of that, constantly stay cardinal to Super Greed and at least 5 tiles away from them

Appears in:

• Mini-boss room (Boss)
• Corpse, The Chest, Dark Room (Enemy)

HP: 60
Stage HP: 25

Attacks & Behavior:

• Behavior
  Walks aimlessly and performs 2 attacks

• Spawn Spider
  Fires 2 Spider enemies towards the player

• Ipecac
  Fires two Ipecac-like projectiles towards the player

• Death
  Upon death Super Sloth drops either a tarot card or the Bob’s Curse item

Tips for the fight:

• Prioritise killing the spiders over damaging Super Sloth

Mini-Bosses – Ultra Pride

Appears in: Mini-boss room (Boss)
HP: 85
Stage HP: 25

Attacks & Behavior:

• Behavior
  Exists as two entities; Edmund (large entity) and Florian (small entity). Both have different attack sets

• Attacks & Behavior (Edmund)
  • Walks aimlessly and performs either of these two attacks:
  • Fires three arcing, homing projectiles towards the player
  • Fires a long line of creep in the closest cardinal direction to the player

• Behavior (Florian)
  • Floats towards the player and fires a homing shot towards them if they’re close enough. Occasionally teleports to a location further from the player.

• Death
  If Edmund is killed last, they drop the Left Hand trinket. If Florian is killed last, they have a chance to drop the Eternal D6 item. Otherwise, Florian drops a random room clear pickup

Tips for the fight:

• Only take the Left Hand if you’re in a bad place in terms of health. The constant red chests may be a good source of soul hearts.

Mini-Bosses – Krampus

Appears in: Devil Room
HP: 60
Stage HP: 45

Attacks & Behavior:

• Behavior
  Floats around aimlessly and performs two attacks

• Brimstone Lasers
  Stops and fires four brimstone lasers in either cardinal or diagonal directions. The lasers rarely can rotate by 90 degrees when fired. This will be telegraphed by Krampus dashing towards the player before firing the lasers

• Projectiles
  Fires a triple shot and then a quad shot towards the player

• Death
  Upon death Krampus will always drop either the Lump of Coal item, or the Head of Krampus item

Tips for the fight:

• [none]

Mini-Bosses – Uriel & Gabriel

This section hosts information for the following bosses:

• Uriel
• Gabriel

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Appears in:

• (Boss) In an Angel Room from an angel statue. It needs to be bombed to summon the boss
• Cathedral (Enemy, extremely rare)

HP: 400

Attacks & Behavior:

• Behavior
  Tries to position himself above the player. Performs 2 attacks

• 5-Shot
  Folds his wings and fires a spread of five shots towards the player shortly after

• Lasers
  Fires lasers in either of these two patterns
  • One laser towards the bottom of the screen
  • Two diagonal lasers downwards

  This attack is telegraphed by Uriel’s glowing hands

Tips for the fight:

• Stay horizontal to Uriel to not get hit by the lasers

Appears in:

• (Boss) In an Angel Room from an angel statue. It needs to be bombed to summon the boss
• Cathedral (Enemy, extremely rare)

HP: 660

Attacks & Behavior:

• Behavior
  Tries to position himself above the player. Performs 3 attacks

• Projectile Ring/Diagonal Lasers
  Folds his wings and either fires out a ring of 12 projectiles or fires lasers in diagonal directions

• Spawn Angelic Baby
  Folds his wings and spawns an Angelic Baby shortly after

• Cardinal Lasers
  Gabriel’s hands start glowing before he fires lasers in cardinal directions

Tips for the fight:

• Prioritise killing the Angelic Babies over damaging Gabriel

Bosses – Introduction

Bosses are very strong monsters found in Boss Rooms at the end of a floor. Bosses need to be killed to progress to the next floor. Boss encounters can have a few properties, listed below

Champions

• Most bosses, just like enemies, have a champion version associated with them, which give them unique abilities/traits

Posthumous/alternate versions

• Certain bosses are strongly related to other bosses i.e. by being their posthumous form (e.g.: Gemini (Normal), Blighted Ovum (posthumous), Steven (Alternate)). These alternate/posthumous versions are usually harder than the base version, but appear later in the game. Alternate versions of bosses often need to be unlocked first before they can appear in runs. They also often have their own specific boss rewards which override the normal Boss Room pool items.

Double Troubles

• Sometimes when entering a boss room, you can stumble upon a Double Trouble. This version of a boss room contains 2 bosses (most of the time, they’re exactly the same (example: Monstro + Monstro)) from the previous chapter

All bosses are listed below in their own sections. Bosses will be ordered in the chapter they appear in, with the exception of alternate or posthumous bosses, which will be grouped with the base boss. In such case the section title will have a number in parentheses, indicating how many versions of this boss there are, including the base boss. (example: Bosses – Monstro (3), Bosses – Harbingers (5)).
If the boss does not have their alternate/posthumous version, the number will not appear (example: Bosses – Baby Plum)

Bosses – Gemini (3)

This section hosts information for the following bosses:

• Gemini
• Blighted Ovum
• Steven

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Appears in:

• Basement, Burning Basement (Boss)
• Caves, Catacombs (Double Trouble)
• Womb, Utero, Scarred Womb, Sheol, Cathedral, The Chest (Enemy)

HP: 280 (each twin has 140)
Description: Simple chaser boss. The main, bigger twin is called Contusion and the smaller one is called Suture.

Behavior:

• Contusion chases the player with Suture attached to them
• Contusion occasionally speeds up, indicated by a different animation, before stopping shortly after to catch their breath for around 3 seconds.
• Suture fires a projectile at the player if they’re in their line of sight. This line of sight can be blocked by solid obstacles.
• When Contusion is killed, Suture detaches and starts floating towards the player. Suture takes heavy knockback from tears during this phase.
• Killing Suture before killing Contusion does not change Contusion’s behavior.

Tips for the fight:

• It’s often better to kill Suture first, as they can become a pretty big annoyance if Contusion is killed first. Suture can easily be reached or even bombed while Contusion is catching his breath.
• Contusion is easy to avoid if there are rocks in the arena, which the player can hide behind.
• If you have a surplus of bombs, you should definetely bomb Suture. Takes only two bombs and makes the fight a lot easier and faster.

Champion versions:

• Cyan:
  • No difference in behavior. Contusion drops a soul heart if killed last.
• Green:
  • Twins start separated. No other difference in behavior

Appears in:

• Cellar (Boss)
• Necropolis (Double Trouble)
• Sheol, Cathedral, The Chest, Dark Room (Enemy)

HP: 140
Description: Posthumous version of Gemini. Significantly harder than the base boss. Twin names are the same as Gemini’s

Behavior:

• Contusion chases the player and occasionally speeds up. Unlike normal Contusion, blighted Contusion does not stop to catch their breath. Blighted Contusion also leaves behind damaging creep behind them
• Suture is now detached from Contusion and is immortal. They slowly float towards the player. They also fire a brimstone laser if the player is horizontal to them. They only die once Contusion is killed.

Tips for the fight:

• The creep is the main source of damage you take in this fight. It’s usually unavoidable, so if you have bombs, use them. This fight is best finished fast.
• Alternatively you can use flight to hover over a rock and pick off blighted Contusion from a safe place. Note that Suture will still be able to hit the player, so you’ll have to change your safe spot every now and then

Appears in:

• Basement, Burning Basement (Boss)
• Sheol (Enemy)

HP: 280 (each twin has 140)
Unlock method: Defeat Basement 40 times
Description: Alternate version of Gemini. Reference to Time ♥♥♥♥ by Edmund McMillen. Slightly harder than the base boss. The twins do not have names, they will be referred to as Big Steven and Little Steven.

Behavior:

• Behavior is very similar, almost identical to Gemini.
• Big Steven chases the player, occasionally speeding up before needing to catch their breath for 3 seconds.
• Little Steven is directly attached to Big Steven. They fire projectiles at the player if they’re in their line of sight, just like Suture.
• Little Steven will detach when Big Steven’s health reaches <50%. After this, they behave identically to an enraged Suture, chasing the player and taking heavy knockback from tears.
• Upon death, Big Steven releases 2 radial bursts of fast and slow moving projectiles.
• Upon death, Little Steven releases a single burst of medium speed projectiles.

Tips for the fight:

• As with Gemini, it’s best to take care of Little Steven first.
• As with Gemini, taking cover behind rocks helps a lot to dodge Big Steven.
• The projectile bursts upon their death have a fixed pattern. These projectiles always go in cardinal and ordinal directions, meaning the player can dodge them easily as long as they are not cardinal or ordinal to the twins when they die.

Bosses – Dingle (2)

This section hosts information for the following bosses:

• Dingle
• Dangle

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Appears in:

• Basement, Burning Basement (Boss)
• Caves, Catacombs, Womb (Double Trouble)
• Chapter III, Chapter IV, Cathedral, The Chest (Enemy)

HP: 300
Description: Simple boss, but can overwhelm the player at times.

Behavior & Attacks:

• Behavior
  Stands still and cycles between three attacks

• Triple Shot
  Smiles and fires a triple shot towards the player shortly after

• Whistle
  Whistles, spawning 1-3 Dips in the process, before firing a triple shot towards the player.

• Dash
  Dashes three times at the player in quick succession, before stopping to catch their breath.

Tips for the fight:

• Always keep your distance during this fight.
• When Dingle is whistling, the Dips might rarely fly out instead of spawning normally, which usually will hit the player if they’re standing close to Dingle.
• You can easily manage dodging 0-4 Dips alongside Dingle, but if more spawn in, they will become difficult to dodge.

Champion versions:

• Black
  • Has one, very fast dash instead of three
  • Spawns Spiders instead of Dips
  • Triple Shot is replaced by 8 shots travelling outwards in ordinal and cardinal directions
• Red
  • Has four, slower dashes instead of three
  • Spawns Red Poop obstacles instead of Dips

Appears in:

• Basement, Burning Basement (Boss)
• Necropolis, Womb (Double Trouble with Brownie)
• Chapter III (Double Trouble with Turdlings)
• The Chest (Enemy)

HP: 375
Unlock method: Defeat ??? as 3 different characters
Description: Alternate version of Dingle. Harder than the base boss.

Attacks & Behavior:

• Behavior
  Stands still and cycles between three attacks

• Triple Shot
  Smiles and fires a triple shot towards the player shortly after

• Whistle
  Whistles, spawning 1-3 Brownie Dips in the process, before firing a triple shot towards the player

• Dash
  Dashes two times in quick succession at the player. Rarely, Dangle may spawn a Corn Mine when beginning the dash, which explodes immediately, poisoning him. When poisoned, Dangle will leave behind damaging creep.

Tips for the fight:

• Keeping distance is even more of a priority with Dangle; his Brownie Dips always fly out instead of spawning in gently, which more often than not will result in the player getting hit if they’re in close-medium range of Dangle.
• Always prioritise killing Brownie Dips, their movement is very erratic. With 3.50 damage, they can be killed in one shot.

Bosses – Duke of Flies (4)

This section hosts information for the following bosses:

• Duke of Flies
• Lil Blub
• The Husk
• Min Min

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Appears in:

• Chapter I (Boss)
• Chapter II (Double Trouble with either Monstro, Rag Man or another Duke)
• Chapter III, Chapter IV, Cathedral, The Chest (Enemy)

HP: 110
Description: Enemy-spawner-type boss. Uses their spawns both as a shield and main attack.

Behavior & Attacks:

• Behavior
  Slowly floats diagonally and cycles between three attacks

• Attack Flies
  Spawns 3 Attack Flies if less than 5 flies are orbiting him

• Large Attack Fly
  Spawns a Large Attack Fly which instead of orbiting Duke, goes straight for the player

• Release Flies
  If >4 Attack Flies are orbiting Duke, he sends them outwards, making them stop orbiting Duke and instead chase the player

• Death
  Duke of Flies bursts into Flies and Attack Flies upon death

Tips for the fight:

• Due to his low HP, it’s usually best to focus on his spawns before they overwhelm the player
• Duke due to his low speed can easily be bombed, lowering his health to 10 HP, making the fight an even bigger cakewalk

Champion versions:

• Green
  • Spawns Moters instead of Large Attack Flies
  • Fires blood shots in ordinal & cardinal directions upon sending flies towards the player
  • Can release flies at any moment, not just when >4 are orbiting Duke.
• Orange
  • +15% size
  • +25% health (for a total of 137.5 HP)
  • Spawns Suckers instead of Large Attack Flies

Appears in:

• Downpour, Dross (Boss)

HP: 130
Description: Alternate, water bloated version of the Duke of Flies. Harder than the base boss

Behavior & Attacks:

• Behavior
  Floats diagonally and cycles between five attacks

• Small Leeches
  Spawns 2-3 Small Leeches which swarm Lil Blub until he performs another attack.

• Large Leech
  Spawns a single, larger Small Leech which chases Isaac

• Radial Burst
  Fires out 6 projectiles in a radial burst

• Leap
  Leaps at the player. Upon landing, either:
  • creates a burst of disorganized arcing projectiles

  or

  • fires out 8 shots in cardinal and ordinal directions

  When low on health, Lil Blub can chain this attack up to five times, and will use this attack more often in general

• Death
  Upon death, Lil Blub bursts into a fountain of projectiles which rain down shortly after.

Tips for the fight:

• A single bomb can bring down Lil Blub to just 30 HP, making the fight way easier
• Keep your distance

Appears in:

• The Catacombs (Boss)
• The Depths, Necropolis (Double Trouble)
• Utero, Sheol, The Chest, Dark Room (Enemy)

HP: 150
Description: Posthumous version of the Duke of Flies. Slightly harder than the base boss

Attacks & Behavior:

• Behavior
  Flies diagonally at high speeds while cycling between three attacks

• Flies & Spiders
  Spawns 1-2 Attack Flies along with a Spider. The Attack Flies will orbit the Husk, blocking shots

• Projectile Spray
  Fires a spray of projectiles, similar to Monstro

• Release Flies
  Releases flies, making them chase the player, while also firing 8 shots in cardinal and ordinal directions.

• Death
  Upon death, the Husk bursts into Flies, Attack Flies and Pooters

Tips for the fight:

• A single bomb can reduce the Husk’s health to just 50 HP, making the fight much easier
• Due to Husk’s low health, the player should prioritise his spawns instead, as they can overwhelm the player if not dealt with
• Keep your distance
• Boom Flies spawned by the Dark Gray champion Husk can damage him, wounding him heavily.

Champion versions:

• Dark Gray
  • Reduced movement speed
  • +15% size
  • +56% HP (for a total of 234)
  • Spawns Boom Flies instead of Spiders/Attack Flies
• Red
  • Increased movement speed
  • -25% size
  • Only performs projectile-based attacks

Appears in: Downpour (Boss)
HP: 280
Description: Alternate version of the Husk, technically also the posthumous version of Lil Blub. Harder than the Husk.

Attacks & Behavior (First Phase):

• Behavior
  Floats slowly towards the player and cycles between two attacks

• Spawn Willo
  Spits out a Willo, which fires at the player before returning to orbit Min Min. These Willos can also fire at the player at random while orbiting Min Min. There is a max limit of 4 Willos orbiting Min Min. After this limit has been reach she can perform the Triple Shot attack.

• Triple Shot
  Causes all orbiting Willos to fire out three projectiles opposite towards Min Min’s position.

• Phase 2
  After reaching around 40% HP, Min Min sheds the corpse she’s hiding in and triggers Phase 2

Attacks & Behavior (Second Phase):

• Behavior
  Floats towards the player and cycles between four attacks

• Attack Kept: Triple Shot
  Min Min can still perform Triple Shot.

• Attack Kept: Spawn Willo
  Min Min can still perform Spawn Willo.

• Spawn Willo (modified)
  Min Min spawns up to 4 Willos at once before performing Triple Shot.

• Release Ring
  Min Min releases all orbiting Willos to chase the player. These Willos come back to Min Min shortly after.

• Lights
  Min Min disappears into the floor and spawns five groups of 1-5 lights at random positions in the room. Willos appear shortly after out of those lights before firing at the player and disappearing back into the light

Tips for the fight:

• High damage is really useful as it allows the player to one-shot Willos. The least amount of damage you need to do so is 6.00
• As always, keeping your distance is a good move
• This is the only Duke fight out of the four on which bombs do not almost insta-kill the boss. Still, 2 bombs can immediately force Min Min into phase 2

Bosses – Harbingers (5) #1

This sections hosts information for the following bosses:

• Famine
• Pestilence
• War
• Death
• Conquest

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Appears in:

• Chapter I (Boss)
• Sheol, Cathedral, The Chest, Dark Room (Enemy)

HP: 240
Unlock method: Defeat Mom
Description: First and arguably the easiest of the harbingers. Very simple attack set. Has two phases

Attacks & Behavior (First Phase):

• Behavior
  Slowly floats vertically in the direction of the player and cycles between two attacks

• Spawn Pooter
  Spawns a Pooter with a limit of 2 in the room at once.

• Charge
  When the player is horizontal to Famine, they charge, going through the wall and reappearing on the other side.

• Phase 2
  Reducing Famine’s HP to around 30% triggers Phase 2

Behavior (Second Phase):

• Behavior
  Famine’s stead and also their body explodes, leaving the head. This head floats towards the player slowly and continuosly shoots a triple shot towards Isaac

Tips for the fight:

• Pooters are usually a big nuisance on this fight, so try to keep forcing Famine to charge by staying horizontal to him.
• While not necessary, circling Famine in phase 2 usually results in the player never getting hit
• While not necessarily a tip for the fight itself, it’s still worth to mention that Famine has a significantly higher chance of spawning as the Basement/Cellar/Burning Basement I or II boss if the player used the Book of Revelations at least once in Chapter I

Champion versions:

• Blue
  • Charges more often
  • Veers slightly towards the player while charging
  • Instead of spawning Pooters, Famine shoots out 6 shots in a hexagonal pattern in a random orientation
  • During Phase 2, Famine shoots a Monstro-like spray instead of his usual triple shot

Appears in:

• Chapter II (Boss)
• Sheol, Cathedral, The Chest, Dark Room (Enemy)

HP: 280
Unlock method: Defeat Mom
Description: Second harbinger. Slightly harder than Famine. Has two phases

Attacks & Behavior (First Phase):

• Behavior
  Floats around randomly, leaving creep behind themselves. Cycles between two attacks

• Ipecac Shot
  Shoots an Ipecac-like shot at the player. This shot leaves damaging creep upon contact.

• Spawn Maggot
  Spawns either a Charger or a Spitty with a maximum of 4 spawns in the room at once.

• Phase 2
  Depleting around 40% of Pestilence’s HP triggers the second phase

Attacks & Behavior (Second Phase):

• Behavior
  Pestilence’s head explodes. Floats around randomly, leaving creep behind themselves. Cycles between two attacks

• Spawn Attack Fly
  Spawns two Attack Flies

• Ipecac Shot
  Shoots an Ipecac-like shot at the player. This shot leaves damaging creep upon contact. Pestilence performs this attack more often in this phase

Tips for the fight:

• The creep can sometimes lock you in if you’re not careful. Be smart about where Pestilence’s Ipecac shots land.
• If you have a surplus of bombs, you can bomb Pestilence twice to instantly initiate the second phase, eliminating most of the challenge in this fight.
• While not necessarily a tip for the fight itself, it’s still worth to mention that Pestilence has a significantly higher chance of spawning as the Caves/Catacombs/Flooded Caves I or II boss if the player used the Book of Revelations at least once on Chapter II

Champion versions:

• Light Gray
  • Leaves slowing, non-damaging white creep instead of the usual, damaging green creep.
  • Spawns Trites instead of Chargers/Spitties in Phase 1
  • Spawns Spiders instead of Attack Flies in Phase 2
  • Shoots 6 shots in a hexagonal pattern in a random orientation instead of the Ipecac shot

Appears in:

• Chapter III (Boss)
• Sheol, Cathedral, The Chest, Dark Room (Enemy)

HP: 500
Unlock method: Defeat Mom
Description: Third horseman. Slightly harder than Pestilence. Has two phases

Behavior & Attacks (First Phase):

• Behavior
  Floats around randomly and cycles between three attacks

• 8-Shot
  Fires eight shots in cardinal and ordinal directions

• Charge
  Charges off-screen and reappears from the other side. War stops charging after he has crossed the screen three times

• Troll Bombs
  Ascends off-screen and spawns five troll bombs, before reappearing from the side shortly after

• Phase 2
  Dropping War’s HP to ~40% triggers Phase 2

Behavior (Second Phase):

• Behavior
  War’s stead blows up, dropping him on the ground. War starts chasing the player, gradually building up speed. Dealing enough damage to War makes him trip, which resets his speed.

Tips for the fight:

• Repositioning the troll bombs using your tears can often save you from getting hit by them, when they knock each other across the screen.
• War can get easily stuck on a bomb in Phase 2, dealing considerable damage to him.
• While not necessarily a tip for the fight itself, it’s still worth to mention that War has a significantly higher chance of spawning as the Depths/Necropolis/Dank Depths I boss if the player used the Book of Revelations at least once on Depths/Necropolis/Dank Depths I

Champion versions:

• Dark Grey
  • +15% size
  • +25% HP (for a total of 625)
  • Summons two mega troll bombs during Troll Bombs instead of five troll bombs
  • Summons a single troll bomb when charging.
  • Shoots six projectiles in a hexagonal pattern when he trips

Bosses – Harbingers (5) #2

Section had to be split due to section text limt

Appears in:

• Chapter III (Boss)
• Sheol, Cathedral, The Chest, Dark Room (Enemy)

HP: 450
Unlock method: Defeat Mom
Description: Fourth horseman. Can sometimes get replaced by Conquest. Significantly harder than War. Has two phases

Attacks & Behavior (First Phase):

• Behavior
  Floats around randomly and cycles between three attacks

• Scythes
  Spawns a single scythe on each of the four walls of the room. These scythes will accelerate towards the player shortly after.

• Homing Scythes
  Spawns two homing scythes in a random position in the room, which chase the player until destroyed

• Hourglass
  Uses an Hourglass-like effect on the player, slowing down their movement and tear speed

• Phase 2
  Depleting enough of Death’s HP triggers the second phase

Behavior (Second Phase):

• Behavior
  Death dismounts his horse and floats around randomly, while the horse charges through the top, middle and then the bottom of the screen until destroyed. Death himself during this will only spawn two Knight enemies periodically.

Tips for the fight:

• Staying close to a wall prevents a non-homing scythe from spawning, this can be used to make dodging this attack easier.
• Homing scythes should be prioritised. So should be the Knights in Phase 2
• Death’s stead takes damage whenever Death takes damage in Phase 2, meaning that focusing on the horse during the second phase is usually a lost cause.
• While not necessarily a tip for the fight itself, it’s still worth to mention that Death has a significantly higher chance of spawning as the Womb/Utero/Scarred Womb I boss if the player used the Book of Revelations at least once on Womb/Utero/Scarred Womb I

Champion versions:

• Black
  • +15% size
  • +25% HP (for a total of 562.5)
  • Can’t use the Hourglass in Phase 1
  • Spawns Kamikaze Leeches instead of homing scythes
  • Spawns Red Maws instead of Knights

Appears in:

• Chapter III (Boss)
• Cathedral, The Chest, Dark Room (Enemy)

HP: 500
Unlock method: Take 10 items from Angel Rooms
Description: Alternate version of Death. Attack set is very similar to War’s. Unlike all the other horsemen, Conquest has only one phase

Attacks & Behavior:

• Behavior
  Floats around randomly and cycles between three attacks

• Charge
  Charges off-screen and reappears on the other side, along with multiple copies of him. These copies all share the same health bar, including Conquest’s.

• Homing Quad Shot
  Shoots out four homing shots in cardinal directions

• Light Beams
  Ascends off-screen and spawns 8-10 Crack of Sky beams in random locations. These beams damage the player

Tips for the fight:

• Stay away from him cardinally; otherwise the homing shots may easily tag you
• Conquest’s clones along with himself take heavy knockback from tears, this can either save the player from being hit or do the opposite.

Bosses – Fistula (2)

This section hosts information for the following bosses:

• Fistula
• Teratoma

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Appears in:

• Caves, Flooded Caves (Boss)
• Caves, Flooded Caves, Depths, Dank Depths, Chapter IV (Enemy, only in small form)
• Depths, Dank Depths, Chapter IV, The Chest (Enemy, in medium form)
• Chapter IV, Corpse, Sheol, Cathedral, The Chest (Enemy, in large form)

HP: 60 (Large), 15 (Medium), 8 (Small)
Description: Low health, but can overwhelm the player with ease.

Behavior:

• Starts in the large form and floats diagonally around the room. Upon death, splits into four medium parts. Each medium part splits into two small parts. Each small part splits into a single Charger, unless it is over a pit/obstacle; in such case, no charger will be spawned.

Tips for the fight:

• As stated in the description, this boss can overwhelm the player quickly. If possible, take care of a single part at a time.
• Having piercing helps a lot in this fight.

Champion versions:

• Dark Gray
  • +15% size
  • +25% HP
  • Decreased movement speed
  • Large part splits into three medium parts instead of the usual four
  • Small parts spawn Boom Flies instead of Chargers

Appears in:

• Utero (Boss)
• Catacombs, Necropolis, Sheol (Enemy, only in small form)
• Catacombs, Chapter III, Sheol, Dark Room, Corpse (Enemy, in medium form)
• Sheol, The Chest, Dark Room, Corpse (Enemy, in large form)

HP: 60 (Large), 15 (Medium), 8 (Small)
Description: Posthumous version of Fistula. On par in terms of difficulty.

Behavior:

• Starts in large form and floats diagonally around the room. Killing the large part spawns three medium parts, which then split into two small parts each if killed. The small parts split into two spiders upon death, unless it dies over a pit/obstacle; in such case, no spiders will spawn.

Tips for the fight:

• Same procedure as with Fistula; take care of a single part at a time.
• By the time you reach this boss most of the times you’ll have build good enough to shred Teratoma to bits in seconds.

Bosses – Gurglings (5) #1

This section hosts information for the following bosses:

• Gurglings
• Turdlings
• Gurdy Jr.
• Gurdy
• Mama Gurdy

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Appears in:

• Basement, Burning Basement (Boss)
• Catacombs (Double Trouble with Turdlings)
• Chapter IV (Enemy)

HP: 120 (60 per Gurgling)
Description: First and youngest of the Gurdy family. Low health, yet very annoying.

Behavior:

• Constantly leaves creep behind themselves and charges at the player if they’re cardinally adjacent to them. Upon finishing the charge they either fire 6 shots in a hexagonal pattern in a random orientation or spawn two attack flies.

Tips for the fight:

• The less time you spend fighting them, the better. Just bomb them and get it over with.
• Try to get them to not charge at all, the more they charge, the higher your chances are of getting hit by some random projectile/creep puddle/attack fly/another gurgling/???????????????????
• Do not hit them when they are charging, they take heavy knockback during this and will usually veer right into the player because of that

Champion versions:

• Black
  • Leaves troll bombs at regular intervals when charging
• Yellow
  • Significantly increased movement speed
  • Three Gurglings spawn instead of two
  • Does not leave creep

Appears in:

• Basement, Burning Basement (Boss)
• Catacombs (Double Trouble with Gurglings)
• Chapter IV (Double Trouble with Dangle)
• The Chest (Enemy)

HP: 100 (50 per each Turdling)
Unlock method: Defeat ??? as three different characters
Description: Alternate version of the Gurglings. Slightly harder than the base boss.

Behavior:

• Crawls around the room randomly. Charges at the player when they’re aligned with them in any cardinal direction. They leave brown, slidy creep behind them when charging. At the end of a charge, they spawn 4 Brownie Corns.

Tips for the fight:

• Prioritise the Brownie Corns over anything else, they are a massive nuisance during the fight.
• As with the normal Gurglings, the less time you spend fighting them, the better; just bomb them and get it over with.

Appears in:

• Chapter II (Boss)
• Depths (Double Trouble)
• Chapter IV, Cathedral, The Chest, Dark Room (Enemy)

HP: 250
Description: Second boss in the Gurdy family. Can be annoying sometimes

Behavior & Attacks:

• Behavior
  Stands still and cycles between three attacks.

• Spawn Pooter
  Spawns a Pooter

• Radial Burst
  Jumps and spawns a radial burst of eight projectiles in cardinal and ordinal directions upon landing.

• Charge
  Charges at the player, bouncing of walls and gradually losing speed before coming to a stop. This attack is used more the less HP Gurdy Jr. has and they will use it constantly when below 50% HP.

Tips for the fight:

• Gurdy Jr. takes heavy knockback when charging. This can be used to slow them down greatly, reducing the chance of the player being hit
• Do not prioritise Pooters, as they will most likely die when Gurdy Jr. performs a charge anyway.

Champion versions:

• Blue
  • Two Gurdy Juniors spawn instead of one
  • -42% size
  • -45% HP for each Gurdy Jr. (137.5 for each Gurdy Jr., 275 in total)
  • Only uses Charge
• Gold
  • +15% size
  • +25% HP (for a total of 312.5)
  • Can’t perform Radial Burst
  • Spawns Super Pooters instead of normal Pooters

Bosses – Gurglings (5) #2

Appears in:

• Caves, Flooded Caves (Boss)
• Chapter IV (Double Trouble)
• The Chest (Enemy)

HP: 595
Description: Third boss in the Gurdy family. Stationary turret and monster spawner

Attacks & Behavior:

• Behavior
  Spawns in the upper middle section of the room, sometimes accompanied by additional enemies, and cycles between four attacks

• Spawn Attack Fly
  Spawns two Attack Flies behind them

• Spawn Pooter
  Spawns a Pooter to their right side

• Spawn Boil
  Spawns two Boils to their sides

• 5-Shot
  Shoots a spread of five shots at the player. Gurdy can fire this spread to their sides and in front of them; which side will be chosen depends on the current position of the player; if the player is in the left third of the room, Gurdy will fire the spread to their left; if the player is in the middle of the room, Gurdy will fire the spread in front of them, and if the player is in the right third of the room, Gurdy will fire the spread to their right side.

Tips for the fight:

• Eliminate all the spawns as soon as possible, especially Boils
• The 5-Shot can be easily dodged with practice.

Champion versions:

• Dark
  • +11% size
  • Can’t perform 5-Shot

Appears in: Womb, Scarred Womb (Boss)
HP: 750
Description: Last boss of the Gurdy family. Expect to get hit at least once if you don’t have flight.

Attacks & Behavior:

• Behavior
  Resides at the top of the screen and cycles between four attacks

• Spikes
  Spawns spikes in random locations. There’s a very small delay before they can deal damage
  • Occasionally Mama Gurdy will retreat off-screen before performing this attack. They will perform Vomit shortly after

• Vomit
  Spews vomit-like projectiles towards the bottom of the screen. These projectiles leave slowing, orange creep upon contact with the ground

• 5-Shot
  Fires 1-5 spreads of five projectiles at the player

• Burst
  Fires a disorganized burst of projectiles at the player

Tips for the fight:

• As stated in the description; expect to get hit if you don’t have flight; the spikes do not give you enough time to react and will usually hit you if you get unlucky with where they spawn.
• The Callus trinket does not work against Mama Gurdy’s spikes
• Weaving from left to right and vice versa is usually enough to dodge the projectile attacks

Bosses – The Haunt (3)

This section hosts information for the following bosses:

• The Haunt
• The Forsaken
• The Heretic

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Appears in:

• Cellar (Boss)
• Chapter III (Double Trouble)
• Chapter III, Chapter IV, Sheol, Cathedral, The Chest, Dark Room (Enemy)

HP: 200
Description: Pretty difficult boss, especially in the first phase if you’re on base stats. Has two phases

Behavior (First Phase):

• Behavior
  Is invulnerable and floats around randomly with three Lil Haunts circling them. After a while, one Lil Haunt becomes vulnerable and starts chasing the player. Killing the first Lil Haunt makes the last two become vulnerable. Killing these two starts the second phase

Attacks & Behavior (Second Phase):

• Behavior
  Loses invulnerability. Floats to the top of the room and starts moving left and right along the wall, while cycling between two attacks. The Haunt will dash towards the player if said player is near the top wall.

• 5-Shot
  Fires a spread of five projectiles towards the bottom of the screen. This attack is not telegraphed

• Brimstone Laser
  Fires a brimstone laser. This attack is slightly telegraphed

Tips for the fight:

• Due to how Lil Haunt AI works, you’re usually going to get cornered by them. Try to kill them quickly if possible
• The best solution for this boss is to just straight up bomb them twice when the second phase begins; this can easily be done by quickly running to the top of the screen and planting a bomb; the Haunt will dash towards it and get stuck on it right before it explodes.
• The best way to not get hit during Phase 2 is to attack the Haunt in between their attacks; after they attack, you get a guaranteed 2-3 second window to attack the boss.
• If you get the Pink champion, for the love of god please bomb it.

Champion versions:

• Black
  • Only two Lil Haunts circle the Haunt; these two L. Haunts will become vulnerable at once
  • Can’t perform Brimstone laser; instead, spawns 1-2 spiders
• Pink
  • -50% HP (for a total of 100)
  • Only one Lil Haunt will circle the Haunt
  • Their brimstone laser attack gets upgraded; instead of one laser heading straight down, two diagonal ones get fired, which also bounce off walls once.
  • 5-Shot gets replaced by a spread of eight shots aimed towards the player

Appears in:

• Flooded Caves, Catacombs (Boss)
• The Chest, Dark Room (Enemy)

HP: 220
Unlock method: Defeat ??? as three different characters
Description: Posthumous version of the Haunt. Actually easier than the base boss

Behavior:

• Behavior
  Starts vulnerable. Spawns 1-2 Bonies and becomes invulnerable as long as at least one Bony is alive. When the Bonies are killed, the Forsaken moves to the center of the room and fires three rotating brimstone lasers, before spawning Bonies again shortly after.

Tips for the fight:

• You can get around 2-3 free hits on the Bonies when they spawn in. Makes fighting them easier.
• Staying horizontal to the Forsaken is usually recommended, as the lasers never spawn facing horizontally.

Champion versions:

• Black
  • Bony spawns get replaced by Black Bonies
  • Spawns 4 Dank Death’s Heads instead of using the brimstone attack

Appears in: Mausoleum (Boss)
HP: 789
Description: Techincally a posthumous version of The Haunt. Is difficult, but also is actually one of the easier Mausoleum bosses. Has two phases

Behavior (First Phase):

• Behavior
  Five Exorcists spawn in a star pattern in the middle of the room. These Exorcists are invincible and resurrect the Heretic, before they get turned into Fanatics. These Fanatics are killable and chase the player, occasionally firing two spiraling shots. During all this, the Heretic is idle and invincible. After killing all enemies in the room, the Heretic becomes vulnerable and Phase 2 begins

Attacks & Behavior (Second Phase):

• NOTE
  The Heretic’s arena always contains several unlit fireplaces, which are used in the Laser attack

• Behavior
  Floats around randomly and cycles between three attacks

• Fireballs
  Lobs seven fireballs towards the player which spawn 6 fires in a hexagonal, fixed pattern upon contact with the ground. Landing locations of the fireballs are marked. After all fireballs explode, the Heretic lunges towards the player. Upon landing, eight lines of fire spread out in cardinal and ordinal directions.

• Laser
  The Heretic lights up 5-6 fireplaces scattered around the edges of the room, before spawning brimstone lasers between them. The order of lighting the fireplaces indicates the direction in which the lasers will be travelling

• Charge
  Floats off-screen before charging in from the side towards the player. In total, the Heretic charges 4 times. Sometimes, the Heretic might disappear instead of biting down on the player, only to reappear and repeat the attack for a theoretical total of five charges.

• Death
  Upon death, Heretic’s eye hits the ground and spawns lines of fire in all cardinal directions

Tips for the fight:

• The exorcists, while appearing as invincible, can be in fact killed in certain circumstances, for example: when a Euthanasia tear hits one of them, they will be killed regardless of their invincibilty. This however has no effect on the resurrection process.
• During the Laser attack, it’s usually best to hug one of the side walls if you can’t keep up with the laser order. Staying in the middle of the room is always a death wish

Bosses – Larry Jr. (4)

This section hosts information for the following bosses:

• Larry Jr.
• The Hollow
• Tuff Twins
• The Shell

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Appears in:

• Basement, Burning Basement (Boss)
• Chapter II (Double Trouble with either Monstro, Pin or another Larry Jr)
• Chapter III (Double Trouble with Sisters Vis)
• Chapter II, Chapter III, Chapter IV, Sheol, The Chest (Enemy)

HP: 22 per segment
Description: Simple, segmented worm-like boss.

Behavior:

• Behavior
  Crawls around the room randomly, turning when met with an obstacle or a wall. Leaves behind poop grid tiles occasionally. Splits into two functioning copies upon destroying a segment if the right conditions are met.

Tips for the fight;

• If possible, stay away and pick Larry off from a distance.
• The poop tiles that Larry leaves behind do not drop pickups. However, exiting the room and returning will make the poops spawn pickups again.
• Sometimes a Grub enemy may replaced a second Larry Jr., if such case occurs, kill the Grub immediately, as they can be a big nuisance

Champion versions:

• Blue
  • +15% size
  • +45% HP (for a total of 32 per segment)
  • Reduced movement speed
  • Does not spawn poop
• Green
  • Sometimes fires a projectile in the direction they’re facing

Appears in:

• Catacombs (Boss)
• Depths (Double Trouble)
• Chapter III, Chapter IV, Sheol (Enemy)

HP: 22 per segment
Description: Posthumous version of Larry Jr. Slightly harder than the base boss

Behavior:

• Behavior
  Flies diagonally around the room, bouncing off walls. Leaves behind poop grid tiles occasionally. Splits into two functional copies of itself when a segment is destroyed, if the right conditions are met.

Tips for the fight:

• As with Larry, keep your distance and pick them off from far away.
• The poop trick with Larry applies to this boss as well.
• As with Larry, a Grub may replace one of the Hollows. If such case occurs, kill the Grub immediately, as they can be a big nuisance

Champion versions:

• Dark Gray
  • +15% size
  • +25% HP (for a total of 27.5 per segment)
  • Each segment has a chance to spawn a Boom Fly when destroyed
• Gold
  • +15% size
  • +25% HP (for a total of 27.5 per segment)
  • Each segment drops a coin upon death
• Green
  • Stops occasionally to fire a triple shot in front of itself
  • Each segment has a chance to spawn a Charger when destroyed

Appears in: Mines (Boss)
HP: 35 per segment
Description: Alternate, mines-themed version of Larry Jr. Unlike during the Larry fight, a Grub cannot replace one of the Tuff Twins. Significantly harder than the base boss

Behavior:

• Behavior
  Crawls around randomly around the room, turning when met with an obstacle or wall. Is indestructible by default because of their rock armor. Spawns Inks if the head segment has armor. Each segment has their own armor. This armor can be destroyed using explosives, whether they be your own bombs or the red bombs spawned by Bomb Grimaces, which always spawn along with the boss. An exposed segment takes damage normally and also spews out blood shots in a small radius if it’s a body segment, or spawns a Sucker if if’s a head segment. Just like Larry Jr., a Tuff Twin can split into two functioning copies upon destroying a segment if the right conditions are met.

Tips for the fight:

• As with Larry Jr., keep your distance
• Explosions aren’t the only thing that can destroy their armor; special tears from the Terra and Sulfuric Acid items can also destroy their armor, eliminating the need to screw around with bombs.
• Their boss room is easily identifiable; it is always a double room (rectangular shape). Unfortunately, this doesn’t always mean that the boss will be the Tuff Twins, as Great Gideon also always spawns in a double room. However, they only spawn in a vertical double room, so if you see a horizontal double room, you can be sure that it’s the Tuff Twins

Appears in: Ashpit (Boss)
HP: 35 per segment
Description: Alternate, mines-themed version of the Hollow. Technically also a posthumous version of the Tuff Twins. On par with difficulty to the Tuff Twins.

Behavior:

• Behavior
  Unlike all the other worm bosses, the Shell always spawns in a pair of worms, 5 segments each. Flies diagonally, bouncing off walls and slightly veering towards the player if they’re in close distance. Same armor mechanic as the Tuff Twins (Bomb Grimaces also spawn), however, the head is indestructible no matter what and is only killed after the segment attached to it is killed. Exposed middle segments shoot triple shots at the player occasionally, while exposed end segments spawn Fly Bombs. Unlike the Tuff Twins, fully armored versions do not do anything and just fly around the room. This worm boss cannot split into two functioning copies, as opposed to all of the other ones.

Tips for the fight:

• Tackle things one at a time; focus on one worm, destroy a part of their armor, kill the segments and you’ve got yourself a breather, repeat. This boss can get quite hectic if multiple segments are exposed at once
• Just like the Tuff Twins, the Shell always spawns in a double room in a random orientation. If you see a horizontal double room as the boss room in the Ashpit, expect the Shell. If you see a vertical one, it can either be the Shell or Great Gideon

Bosses – Monstro (3)

This section hosts information for the following bosses:

• Monstro
• Monstro II
• Gish

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Appears in:

• Basement, Burning Basement (Boss)
• Chapter II (Double Trouble with either Larry Jr., Fistula, Duke of Flies or another Monstro)
• Chapter III, Chapter IV, Cathedral, The Chest, Dark Room (Enemy)

HP: 250
Description: Baby’s first boss. Simple attack set, that at the same time doesn’t consist of moving in a random direction

Attacks & Behavior:

• Behavior
  Stands still and cycles between three attacks

• Hop
  Hops towards the player

• Spray
  Fires a spray of disorganized projectiles towards the player

• Leap
  Leaps off-screen and attempts to land on the player. Releases a spray of projectiles in all directions upon impact

Tips for the fight:

• Monstro can sometimes spawn with enemies alongside them. Prioritise them before dealing with Monstro
• Other than that it’s just dodging their attacks while dealing damage
• If you get the red champion version, it’s best to just bomb one of the red Monstros and finish them off to make the fight way easier

Champion versions:

• Gray
  • +15% size
  • +25% HP (for a total of 312.5)
  • Can’t perform Leap
• Red
  • Two Monstros spawn instead of one
  • -25% size
  • -55% HP (112.5 HP per each red Monstro, 225 in total)

Appears in:

• Depths, Dank Depths (Boss)
• Sheol, Cathedral, The Chest, Dark Room (Enemy)

HP: 633
Description: Posthumous version of Monstro. Significantly tankier, but not much harder

Attacks & Behavior:

• Behavior
  Stands still and cycles between three attacks

• Hop
  Hops towards the player

• Brimstone Laser
  Fires a brimstone laser horizontally if the player is in the line of fire.

• Double Leap
  Leaps towards the player, attempting to land on them. Fires 8 projectiles in cardinal and ordinal directions upon impact. Afterwards, Monstro II repeats the process, but instead spawns 4 Suckers upon impact.

Tips for the fight:

• After spawning the four Suckers, the player can provoke Monstro II to fire their brimstone laser, which will eliminate most of the spawned Suckers
  • Monstro II landing on top of the Suckers kills them as well

Champion versions:

• Red
  • -20% size
  • Faster movement speed and attack speed
  • Spawns two Suckers instead of four

Appears in:

• Depths, Dank Depths (Boss)
• Dark Room (Enemy)

HP: 633
Unlock method: Complete Chapter III 20 times
Description: Alternate version of Monstro II. Easier than Monstro II.

Attacks & Behavior:

• Behavior
  Stands still and cycles between three attacks

• Hop
  Hops towards the player

• Tar Bomb
  Fires an Ipecac-like shot towards the player. This shot leaves black, slowing, yet non-damaging creep behind upon contact with the ground

• Double Leap
  Functions exactly to Monstro II’s Double Leap, except the first leap spawns a puddle of black creep, and the second leap spawns two Clots

Tips for the fight:

• Prioritise Clots, they can catch the player off guard with ease
• If you have flight, you can just float over an obstacle to prevent Gish from moving, since they then will have nowhere to move to. Gish may still rarely fire a tar bomb though

Bosses – Pin (4)

This section hosts information for the following bosses:

• Pin
• Wormwood
• The Frail
• Scolex

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Appears in:

• Cellar (Boss)
• Chapter II (Double Trouble with Mega Fatty, Larry Jr., Chub, Blighted Ovum or another Pin)
• Chapter III, Chapter IV, The Chest (Enemy)

HP: 100
Description: Worm-type boss, leaps out of the floor to attack the player.

Attacks & Behavior:

• Behavior
  Cycles between two attacks

• Leap
  Leaps from a distance of 4-6 tiles towards the player, often firing four shots in ordinal directions from its last segment. Retreats away from the player after burrowing back into the ground

• Bomb Shot
  Fires an Ipecac-like shot towards the player

Tips for the fight:

• Do not get cornered
• A single bomb can instakill Pin, so if you have a surplus of bombs, you know what to do.

Champion versions:

• Black
  • Shoots out 6 spiraling shots instead of the Bomb Shot, similar to the Nightcrawler enemy
  • Shoots 6 blood shots instead of 4 when leaping

Appears in: Downpour, Dross (Boss)
HP: 200
Description: Downpour-themed version of Pin. Significantly harder than the base boss.

Attacks & Behavior:

• Behavior
  Cycles between two attacks, performs a special attack once at 33% health

• Lunge
  Lunges from a pit towards the player, releasing 4 shots in cardinal directions once, chasing them afterwards in a small zig-zag pattern. Returns back to the nearest pit after a while.

• Projectile Spray
  Emerges from a pit and fires a Monstro-like spray of projectiles towards the player before swiftly descending back into the water

• 33% HP
  At 33% HP, Wormwood abandons their current waypoint and paths to the nearest pit. After fully submerging, Wormwood starts poking the player from underneath the floor, spawning Pit grid tiles. Wormwood pokes the player 3-6 times in total before trying to breach the wall. This will be telegraphed by a crack appearing at the left/right wall at the player’s current horizontal position.
  Upon breaching the wall, Wormwood flies out horizontally at very high speeds, spawning 3 Small Leeches in the process

Tips for the fight:

• For some reason, when Wormwood hasn’t fired the 4 shots after they have lunged, they can’t be damaged, meaning you’ll have to wait for Wormwood to fire the four shots before you can hit them.
• The pit tiles spawned by Wormwood, when they’re at low health, can sometimes make dead ends, which can become fatal, especially if the player doesn’t have flight. Be wary of where Wormwood is spawning these grid tiles.

Appears in: Catacombs, Flooded Caves (Boss)
HP: 300 (100 in first phase, 200 in second phase)
Unlock method: Defeat ??? as three different characters
Description: Posthumous version of Pin. Harder than the base boss. Has two phases

Attacks & Behavior (First Phase):

• Behaves identically to Pin. Dealing 100 damage to the Frail triggers Phase 2

Attacks & Behavior (Second Phase):

• Behavior
  Cycles between three attacks

• Leap
  Leaps out of the ground towards the player, often firing out 4 shots in ordinal directions, each of which then split into four more shots in cardinal or ordinal directions

• Brimstone Laser
  Emerges head first and either:
  • Fires two Brimstone Lasers towards the player’s position one after another
  • Fires a single, spinning Brimstone Laser, which follows the player’s movements

• Creep Burst
  Emerges tail first and a burst of white projectiles in all directions. These projectiles leave white, slowing yet non-damaging creep upon landing

Tips for the fight:

• Keep your distance, especially when The Frail is leaping
• If you cannot afford to get hit, you should focus on dodging all of Frail’s leaps. You get an attack window when The Frail is using their brimstone laser attacks.

Champion versions:

• Black
  • Phase 1 gets skipped completely, including health, meaning the Frail has 200 HP instead of 300

Appears in: Womb, Scarred Womb (Boss)
HP: 300
Description: Womb-themed Pin. Hardy, but has a pretty simple attack set.

Attacks & Behavior:

• Behavior
  Is invulnerable except for their blinking, red tail segment, which takes damage normally.

• Leap
  Leaps towards the player from a distance of around 4-6 tiles. Unlike Pin or Frail, Scolex does not fire out blood shots when flying through the air.

• Projectile Spray
  Emerges head first and fires a Monstro-like spray of projectiles at the player.

• Blood Bombs
  Emerges tail first and fires three Ipecac-like shots towards the player

Tips for the boss:

• This boss is a patience test more than anything, just keep dodging. The Blood Bombs attack is a pretty good attack window for the player

Bosses – Widow (2)

This section hosts information for the following bosses:

• Widow
• The Wretched

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Appears in:

• Cellar (Boss)
• Scarred Womb, Cathedral, The Chest, Dark Room (Enemy)

HP: 130
Description: A Trite on drugs. Relatively difficult.

Attacks & Behavior:

• Behavior
  Stands still and cycles between three attacks

• Hop
  Hops towards the player

• Spawn Sack
  Spawns a Sack enemy, while also leaving a puddle of white, slowing yet non-damaging creep

• Spawn Spider
  Spits out a Spider

Tips for the fight:

• The Widow can kill her own spawns if she lands on top of them. This can be used to quickly deal with the Sacks she spawns
• Running in a big circle around the arena is usually a good way to dodge her attacks
• A single bomb can bring her down to 30 HP

Champion versions:

• Red
  • -50% size
  • Spawns Boils instead of Sacks
  • Spawns Attack Flies instead of Spiders
• Black
  • Spawns Big Spiders instead of Sacks
  • White Creep turns into Black Creep, no functional difference
  • Fires out 6 blood shots in a hexagonal pattern in a random orientation instead of spawning spiders

Appears in:

• Catacombs (Boss)
• Depths (Double Trouble)
• Utero, Sheol, The Chest, Dark Room (Enemy)

HP: 215
Description: Posthumous version of the Widow. Slightly harder than the base boss

Attacks & Behavior:

• Behavior
  Stands still and cycles between three attacks

• Hop
  Hops towards the player

• Radial Burst
  Leaves a puddle of white, harmless creep and fires out 8 shots in cardinal and ordinal directions

• Spawn Random Spider
  Spawns either:
  • 2 Spiders
  • 1 Big Spider
  • 1 Trite

• Death
  Spawns 1-3 Spiders right when her health goes down to 0. Stay alert, as it can easily catch you off guard

Tips for the fight:

• The Wretched can kill her own spawns if she lands on top of them. This can be used to quickly deal with the spiders she spawns
• Running in a big circle around the arena is usually a good way to dodge her attacks
• By the time you reach Chapter II you should have a handful of bombs on you. Two bombs is enough to bring the Wretched down to just 15 HP

Bosses – Little Horn (2)

This section hosts information for the following bosses:

• Little Horn
• Big Horn

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Appears in:

• Chapter I (Boss)
• Depths, Necropolis (Double Trouble with Rag Man)
• Dank Depths (Double Trouble with Loki)
• Womb, Utero (Double Trouble with The Fallen)
• Sheol, The Chest, Dark Room (Enemy)

HP: 200
Unlock method: Defeat ??? as three different characters
Description: Stubby demon that uses ranged attacks and tries its best to avoid the player, often causing damage to themselves in the process.

Attacks & Behavior:

• Behavior
  Floats away from the player and cycles between six attacks

• Teleport
  Spawns a pitfall under itself and teleports in a random location away from the player

• Spawn Dark Ball
  Spawns a Dark Ball

• Spawn Pitfall
  Spawns 3-5 pitfalls which move outwards

• Spawn Pitfall Trap
  Spawns a single pitfall under itself, which stays for several seconds before disappearing

• (Mega) Troll Bomb
  Spawns a pitfall under itself and throws a troll bomb/mega troll bomb into it shortly after. The bomb then appears near the player

• Chain Teleport
  Jumps into a pitfall, while leaving a troll bomb behind themself, and appears shortly after in a random place. The process is repeated 3-5 times

Tips for the fight:

• It’s not uncommon to see fireplaces in Little Horn’s arena. The player can make Little Horn retreat towards them, potentially dealing heavy damage to them.
• Another way in which Little Horn can damage themself is by taking damage from their own troll bomb. There aren’t many good ways to force that to happen though, it’s mostly just a matter of luck
• If you encounter the Orange champion and haven’t got any armor, say goodbye to your Deal Room chance; the orange bombs are really janky and at times can deal contact damage without the player actually being near one.

Champion versions:

• Orange
  • Can’t spawn Mega Troll Bombs
  • Instead of a Dark Ball, Little Horn spits out an orange bomb towards the player. This bomb deals contact damage and leaves a damaging fire upon exploding.
  • Little Horn also throws orange bombs instead of normal troll bombs, except when using the Chain Teleport attack
• Black
  • Cannot attack with troll bombs or pits of any kind. Instead, Little Horn only spawns Dark Balls and teleports around

Appears in:

• Chapter II (Boss)
• The Chest, Dark Room (Enemy)

HP: 480
Unlock method: Defeat ??? as 6 different characters
Description: Adult version of Little Horn. Harder than the base boss

Attacks & Behavior:

• Behavior
  Stationary. Uses their arms and head to attack the player. Has 4 arm attacks and 3 head attacks

• Arm Attacks
  2-3 pitfall-like holes spawn, out of which Big Horn’s hands come out shortly after. These hands can either:
  • Throw a single troll bomb towards the player
  • Throw a spread of three troll bombs towards the player. These bombs have a chance to have the effects of Hot Bombs, or Sad Bombs if Big Horn is fought in the Flooded Caves.
  • Quickly slap the ground three times, while simultaneously moving towards the player
  • Bring out a Little Horn, which spawns three Dark Balls. If Big Horn dies when holding Little Horn, Little Horn will continue the fight, albeit with very low HP

• Head Attacks
  A single, slightly larger pitfall spawns, out of which Big Horn comes out shortly after. Big Horn can either:
  • Spawn two, large Dark Balls, which move diagonally across the room
  • Spawn a single, large Dark Ball, which homes in on the player
  • Combine the two previous attacks and spawn two diagonally moving balls and one homing one

Tips for the fight:

• Prioritise killing any Dark Balls that are on the screen
• After Big Horn has spat out the Dark Ball(s), there is a brief window where a bomb can be knocked into their mouth, dealing considerable damage.

Bosses – Rag Man (2)

This section hosts information for the following bosses:

• Rag Man
• Rag Mega

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Appears in:

• Cellar, Burning Basement (Boss)
• Depths, Necropolis (Double Trouble with Little Horn)
• Mausoleum, Sheol, Cathedral, The Chest, Dark Room (Enemy)

HP: 200
Unlock method: Defeat ??? as three different characters
Description: All-around difficult boss. When you see him in the Basement, you might as well just restart.

Attacks & Behavior:

• Behavior
  Walks around randomly and cycles between three attacks

• Homing Shots
  Fires 1, 3 or 5 homing shots at the player in quick succession

• Spawn Ragling
  Ragman throws his head, which rolls around, gradually losing speed. When the head has come to a stop, a Ragling spawns from it. Ragman himself during this attack will behave like a Gusher, walking around randomly and spewing shots. As opposed to normal Gushers, Rag Man’s shots will home in on the player if they’re close enough, indicated by their purple appearance

• Revive
  Briefly stops and revives any surrounding Ragling corpses. This attack always heals Rag Man for 10 HP

Tips for the fight:

• This fight becomes hectic very fast. With base stats, Rag Man’s head and his Raglings have too much HP to kill them quick enough to not overwhelm the player after a while.
• Rag Man’s shots home in extremely well, even being able to perform a tight loop to reach the player. Stay far away from them
• If you have two or more bombs and got no use for them, you might as well bomb Rag Man twice and finish him off before he has a chance to attack.

Champion versions:

• Black
  • Rag Man’s head spawns 2 Spiders instead of a Ragling
  • Can’t revive Raglings. Instead, Rag Man fires a Monstro-like spread towards the player
• Orange
  • Can’t fire homing shots

Appears in:

• Chapter II (Boss)
• Mausoleum, The Chest, Dark Room (Enemy)

HP: 120
Unlock method: Defeat ??? as six different characters
Description: Posthumous/evolved version of Rag Man. Easier or harder, depending on how you handle the fight

Attacks & Behavior:

• Behavior
  Floats diagonally and cycles between three attacks. Has 3 invincible balls orbiting him. These balls detach from Rag Mega one by one and start chasing the player after Rag Mega has taken enough damage

• Spawn Ragling
  Spawns a Ragling

• Resurrection Beams
  Spawns three beams, which revive any dead Raglings they hit

• Invincibility
  Wraps himself in bandages, becoming invincible for a short while

Tips for the fight:

• This isn’t even a suggestion, just bomb him

Bosses – Baby Plum

Appears in:

• Chapter I (Boss)
• Sheol, Cathedral (Enemy)

HP: 234
Description: Boss version of a Red Boom Fly. Fairly simple boss

Attacks & Behavior:

• Behavior
  Floats towards the player and cycles between three attacks

• Twirl
  Twirls towards the player, sending out a spiral of projectiles

• Slam
  Slams into the ground, spawning a puddle of creep and firing out two rings of fast and slow projectiles

• Bounce
  Spits a diagonal stream of projectiles, propelling herself backwards and bouncing off any walls

• Death
  Upon death, Baby Plum releases a ring of 10 projectiles

Tips for the fight:

• The player doesn’t necessarily have to kill Baby Plum to end the fight. Baby Plum can be spared by not dealing any damage to her for around 20-40 seconds. This will make Baby Plum fly off-screen and award the player the Plum Flute item. Subsequent spares also reward the player with the Plum Flute.
• Baby Plum will often spawn with a few Red Boom Flies alongside her. Prioritise them
• Keep your distance

Bosses – Rainmaker

Appears in: Downpour (Boss)
HP: 240
Description: Simple, yet tricky at the same time.

Attacks & Behavior:

• Behavior
  Very slowly floats towards the player and cycles between four attacks

• Water Line
  Spawns a horizontal line on both sides, 6 projectiles each and fires them towards the player shortly after

• Water Ring
  Spawns a ring of 12 projectiles around themself and fires them towards the player shortly after

• Bubble
  Spawns a large bubble above their head and pops it, releasing a burst of projectiles in random directions

• Twirl
  Twirls towards the player while spawning projectiles near themself. These projectiles hover in the air for a short time before being fired towards the player. At the end of this attack Rainmaker releases an additional radial burst in cardinal and ordinal directions

• Death
  Upon death, the Rainmaker kills all of their projectiles, effectively turning the room into a safe space

Tips for the fight:

• Due to their Water Line attack, staying horizontal to Rainmaker is generally a bad move
• Walking in a big circle around the room is an easy and good way to dodge Rainmaker’s attacks

Bosses – Clog

Appears in: Dross (Boss)
HP: 420
Description: Tanky, yet simple. Turns into a mess if not handled correctly

Attacks & Behavior:

• Behavior
  Sits in the middle of the screen and cycles between four attacks

• Spawn Drip
  Spawns Drips until there are 2-4 of them in the room

• Spawn Poop
  Creates three lines of farts. Each fart has a chance to spawn a poop. 1-2 of these poops will be Corny Poops

• Spin
  Spins, causing the water to circulate around them, catching the player and any other entities in its current. Clog only performs this attack if there are >2 Drips in the room

• Projectile Spirals
  Shoots out four spiraling lines of projectiles. These lines can either consist of fast projectiles, with large gaps in between, or slow projectiles with small gaps in between

• Death
  Upon death, Clog kills all Drips in the room. Other entities unaffected

Tips for the fight:

• During the Spin attack, try to stay against the current, picking off any Drips that come by. Do this especially when there are any poops/corny poops in the room
• The Flush! active item insta-kills Clog
• The player will be unaffected by the water current if they have flight
• Butt Bombs heal Clog, making them ineffective against them
• Spawn Poop is completely RNG-dependent when it comes to getting hit. The poop lines can be in any orientation, and rarely you may get unlucky enough to end up with a corny poop right in your face

Bosses – Colostomia

Appears in: Dross (Boss)
HP: 380
Description: A sack of sh#t, both literally and figuratively. Explosion-themed in regard to its attacks. Expect to lose some HP on this boss. Has two phases

Attacks & Behavior (First Phase):

• Behavior
  Stands still and cycles between two attacks

• Slide
  Slides in the closest cardinal direction to the player, releasing shots perpendicularily from both sides and creating trails of explosive gas

• Butt Bomb
  Fires a Butt Bomb towards the player. This bomb can blow up the nearby explosive gas

• Phase 2
  Dropping Colostomia to 50% HP triggers the second phase

Attacks & Behavior (Second Phase):

• Behavior
  The bag containing Colostomia explodes, leaving Colostomia adhered to the floor. This new form cycles between three attacks and constantly generates harmful brown creep in its vicinity

• Leap
  Repositions itself by jumping to another nearby location, releasing 8 shots upon landing

• Fart
  Farts, creating a ring of explosive gas

• Butt Bombs
  Fires 2 Butt Bombs towards the player

Tips for the fight:

• Try to get Colostomia to slide for as little distance as possible, in order to limit how many projectiles they fire out.
• Be wary of where the explosive gas is. One wrong slide can cover the entire room with gas
• Unlike the first phase, the second phase is fairly easy. Once you’ve killed the first phase you basically won the fight. Just keep your distance.

Bosses – Turdlet

Appears in: Dross (Boss)
HP: 180
Description: Fairly simple segmented boss, but can catch the player off guard at times. Has two phases

Behavior (First Phase):

• Behavior
  Always spawns in 5 segments, including the head. Constantly moves in wide turns to reach the player. Occasionally huddles together and springs back shortly after, moving very fast and bouncing off any obstacles or walls. At around 40% HP Turdlet enters Phase 2

Behavior (Second Phase):

• Behavior
  Splits into two copies of itself, each of which have two segments. These copies have the same AI as Turdlet’s first phase

Tips for the fight:

• This boss is so simple and fragile that there are no real tips for them.

Bosses – Chub (4)

This section hosts information for the following bosses:

• Chub
• CHAD
• Carrior Queen
• The Matriarch

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Appears in:

• Caves, Flooded Caves (Boss)
• Chapter II (Double Trouble with Pin)
• Chapter III (Double Trouble with Gurglings or another Chub
• Chapter III, Chapter IV, Corpse, Cathedral, The Chest, Dark Room (Enemy)

HP: 350
Description: Boss version of the Chargers. Simple, but tanky.

Attacks & Behavior:

• Behavior
  Crawls around randomly

• Charge
  Charges at the player when they’re aligned cardinally to it. Chub can eat bombs while charging, stopping them briefly before dealing considerable damage to them

• Spawn Charger
  Spawns a Charger

Tips for the fight:

• This fight is a test of patience more than anything, especially with base stats. You can speed up the process by bombing Chub
• Prioritise killing Chub’s spawns

Champion versions:

• Cyan
  • Reduced movement speed
  • +15% size
  • +25% HP (for a total of 437.5)
  • Spawns Boils instead of Chargers
• Orange
  • Increased movement speed
  • -15% size
  • -15% HP (for a total of 297.5)
  • Spawns Spitties instead of Chargers

Appears in:

• Caves, Flooded Caves (Boss)
• The Chest (Enemy)

HP: 350
Unlock method: Complete Chapter II 30 times
Description: Alternate version of Chub. Slightly harder than the base boss

Behavior:

• Behavior
  CHAD’s behavior is identical to Chub’s with a few exceptions, these are:
  • CHAD spawns Suckers instead of Chargers
  • CHAD gets faster and smaller the less HP they have

Tips for the fight:

• The tips for Chub also apply for this boss.

Appears in:

• Catacombs (Boss)
• The Chest, Dark Room (Enemy)

HP: 350
Description: Posthumous version of Chub. Significantly tankier than the base boss. Has two phases

Attacks & Behavior (First Phase):

• Behavior
  Crawls around randomly. Is invulnerable, except for the last, fleshy segment which takes damage normally

• Spawn Red Poop
  Spawns a permanent red poop

• Charge
  Charges at the player when they’re aligned cardinally to it. Carrior Queen can eat bombs while charging, stopping them briefly before dealing considerable damage to them

• Phase 2
  Bringing Carrior Queen down to 50% HP triggers the second phase

Behavior (Second Phase):

• Behavior
  Crawls diagonally, bouncing off of any rocks, walls or poops

Tips for the fight:

• Don’t bother with trying to damage their behind. If you have bombs, use them

Champion versions:

• Pink
  • Increased movement speed
  • +100% HP (for a total of 700)
  • Phase 2 nonexistent
  • Occasionally spawns small Heart enemies, which damage Carrior Queen when they die

Appears in:

• Womb, Scarred Womb (Boss)
• Cathedral, The Chest (Enemy)

HP: 700
Unlock method: Defeat ??? as 6 different characters
Description: A mix of Chub and Fistula. Significantly harder than the base boss. Has three phases

Attacks & Behavior (First Phase):

• Behavior
  Hops randomly around the room and cycles between three attacks. Spawns 1-2 small Fistulas after taking 140 damage, and 100 damage afterwards

• Spawn Fistuloid
  Sacrifices 30 HP to spawn a Fistuloid, which either chases the player or orbits the Matriarch, with a cap of 4 on screen at once.

• Chubbers
  Jumps and spawns 8 Chubber projectiles in cardinal and ordinal direction upon landing, which then rebound back to the Matriarch

• Projectile
  Spews out a projectile, which leaves creep in its trajectory and also upon landing

• Phase 2
  Bringing the Matriarch down to around 50% HP triggers Phase 2

Attacks & Behavior (Second Phase):

• Behavior
  No visual indication of the phase switch. Retains all attacks from Phase 1

• Fistuloid Swarm
  Rapidly spawns Fistuloids, which blink red, before dying, and shooting their maggots in the process.

• Phase 3
  Bringing the Matriarch down to around 20% HP triggers Phase 3

Behavior (Third Phase):

• Behavior
  Plays a short stagger animation before splitting into one medium Fistula, two small Fistulas, a Fistuloid and a low health Chub. The behavior of the Chub is slightly different; Chub will always charge upon spawning and will spit any bombs that they eat back out towards the player.

Tips for the fight:

• Let’s face it, this fight is a mess. Pay attention to anything that’s either near your character or anything that’s approaching it, and react accordingly. Especially watch out for the creep-leaving projectiles

Bosses – Dark One (2)

This section hosts information for the following bosses:

• Dark One
• Adversary

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Appears in:

• Catacombs (Boss)
• Sheol, The Chest, Dark Room (Enemy)

HP: 520
Description: Fairly simple attack set, not much else to say

Attacks & Behavior:

• Behavior
  Floats around randomly and cycles between four attacks

• Darkness
  Dims the room, causing a Curse of Darkness-esque effect for a short time

• Projectile Burst
  Fires out a ring of 12 projectiles in all directions

• Charge
  Charges towards either edge of the screen and wraps around two times before stopping. Uses this attack more often if the player is horizontal to the Dark One

• Brimstone
  If the player is below the Dark One, they have a chance of firing a Brimstone laser downwards

Tips for the fight:

• For obvious reasons do not stay below the Dark One. Staying horizontal to them isn’t a good move either, unless you want to fight for eternity, since the Dark One is hard to hit when charging. Staying above the Dark One gives you the biggest window to attack, but watch out for the ring of projectiles, as it can easily catch you off guard

Appears in:

• Necropolis (Boss)
• Sheol, The Chest, Dark Room (Enemy)

HP: 520
Description: Posthumous version of the Dark One. Harder than the base boss

Attacks & Behavior:

• Behavior
  Floats around randomly and cycles between four attacks

• Darkness
  Dims the room, causing a Curse of Darkness-esque effect for a short time

• Spawn Spiders
  Spawns 3 Spiders

• Leap
  Flies off-screen and tries to land on the player. Creates rock waves stretching for ~3 tiles upon landing

• Brimstone
  If the player is adjacent cardinally to the Adversary, they fire a Brimstone laser in the closest cardinal direction to the player. This beam bends slightly and follows the player’s movements

Tips for the fight:

• The Brimstone beam curves significantly the further you are from the boss. Stay close to them in order to avoid damage
• Prioritise killing the spiders

Bosses – Mega Fatty (3)

This section hosts information for the following bosses:

• Mega Fatty
• The Cage
• Sisters Vis

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Appears in:

• Caves, Flooded Caves (Boss)
• Chapter II (Double Trouble with Pin)
• Chapter III (Double Trouble with another Mega Fatty)
• Chapter III, Chapter IV, Sheol, Cathedral, The Chest, Dark Room (Enemy)

HP: 600
Description: Absolute tank. Fights with them are usually very long and frustrating

Attacks & Behavior:

• Behavior
  Stands still and cycles between four attacks

• Leap
  Leaps off-screen and tries to land on the player. Spawns a puddle of harmful creep on impact

• Fast Leap
  Leaps off-screen extremely fast and tries to land on the player. Spawns a puddle of harmful creep on impact

• Vomit
  Breathes in, pulling in any entities towards them and vomits out a stream of projectiles into the air, which come back down shortly after. This stream constantly aims at the player’s position

• Fart
  Farts and either spawns 1-3 Dips or launches a spray of projectiles behind them

Tips for the fight:

• Keep moving to avoid the Fast Leap.
• Prioritise damaging Mega Fatty over their spawns, only killing them when they’re in your way. The less time the fight takes, the better

Champion versions:

• Brown
  • +15% HP (for a total of 690)
  • Can’t perform Vomit
  • Releases 3-4 rock waves upon impact when performing Leap (not Fast Leap). These waves spawn in a random orientation, but they usually go in cardinal directions, slightly shifted to the left/right depending on the player’s position
• Red
  • -33% size
  • -10% HP (for a total of 540)
  • Creates Red Poop instead of Dips
  • Shoots out 6 projectiles in a hexagonal pattern upon landing when performing Fast Leap
  • Fires out four spiraling lines of projectiles which radiate outward during Vomit instead of the usual stream of projectiles

Appears in:

• Depths (Boss)
• Womb, Utero (Double Trouble)
• Sheol, The Chest, Dark Room (Enemy)

HP: 800
Description: Posthumous version of Mega Fatty. Even tankier than the base boss (even has more HP than Mom), however the difficulty is sort of on par.

Attacks & Behavior:

• Behavior
  Stands still and cycles between four attacks

• Leap
  Leaps off-screen and tries to land on the player. Spawns 4 rock waves and a puddle of creep upon impact

• Spawn Vis
  Spawns a grey-colored Vis. The change is purely cosmetic

• Vomit
  Vomits out 4 spiraling lines of projectiles which radiate outward. These lines have a chance to have holes in them, giving more room to dodge.

• Roll
  Curls up into a ball and rolls around the room, bouncing off walls. With enough knockback, Cage’s trajectory can be changed.

Tips for the fight:

• You have way more reaction time with the Cage than with Mega Fatty. The Cage makes up for that by having slightly more difficult attacks however
• Unlike during the Mega Fatty fight, prioritise killing Cage’s spawns over dealing damage to the Cage
• The “Slow” status effect works on the Cage in a detrimental way to the player, as it can make dodging Vomit harder.
• Staying diagonal to the Cage usually lets you avoid the rock waves

Champion versions:

• Green
  • Periodically leaves harmful green creep
  • Can’t spawn Vises
• Pink
  • Two Cages spawn instead of one
  • -50% HP (400 for each pink Cage, 800 in total)
  • Can’t leap

Appears in:

• Chapter III, Utero, Scarred Womb (Boss)
• Chapter III (Double Trouble with Larry Jr.)
• Chapter IV (Double Trouble with either the Husk or Lokii)
• Sheol, The Chest, Dark Room (Enemy)

HP: 700 (350 per sister)
Unlock method: Defeat ??? as 6 different characters
Description: Technically an alternate version of The Cage, suggested by visual and attack similarities. Surprisingly easier than the Cage, even easier than Mega Fatty in fact. Has two phases

Attacks & Behavior (First Phase):

• Behavior
  Spawns in two. Stands still and cycles between three attacks

• Roll
  Both sisters curl up in balls and start rolling around the room, bouncing off walls and eachother. One sister will leave green creep and start rolling towards the player, while the other will leave brown creep and roll away from the player. One sister stops rolling before the other, opens their chest, faces the player in the closest cardinal direction to them, and does either one of these two attacks:
  • Fires a gigantic Brimstone beam, which rarely also sweeps back and forth in a wide arc
  • Fires 2-4 lines of slow-moving projectiles

• Spawn Vis/Begotten
  Each sister spawns one Vis or Begotten, for a total of 2 Vises/Begottens

• Laser
  Both sisters leap into the air and land on either the horizontal or vertical walls before opening their chests and firing a massive brimstone laser in front of them for a short time.

• Phase 2
  Killing either of the two sisters triggers Phase 2

Behavior (Second Phase):

• Behavior
  The remaining sister becomes enraged. When enraged, they’re unable to leap, and will always fire a laser or the projectile waves after rolling. If the remaining sister was the one that was spawning brown creep, the creep will be green instead

Tips for the fight:

• The only attack that can catch the player off guard are the rolls they often perform. Just like the Cage, a Sister Vis can be redirected if enough knockback is dealt to them
• Their laser attack gives the player a very large attack window
• Try to distribute damage evenly along the two sisters, as focusing on just one will make the other one prematurely enraged

Bosses – Mega Maw (2)

This section hosts information for the following bosses:

• Mega Maw
• The Gate

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Appears in:

• Caves, Flooded Caves (Boss)
• Chapter IV, Sheol, Cathedral, The Chest, Dark Room (Enemy)

HP: 350
Description: Boss version of the Maw enemy. Relatively difficult attack set

Attacks & Behavior:

• Behavior
  Stationary. Cycles between three attacks

• Projectile Spray
  Breathes in and fires a Monstro-like spray of projectiles at the player shortly after

• Spawn Hopper
  Spawns a hopper

• Fire
  Shoots out fast fire projectiles in either of these three patterns:
  • Two rings of five spread out flames. Each ring rotates in different directions
  • A ring of nine flames
  • A rotating ring of nine flames

Tips for the fight:

• Focus on dodging the fire attacks; non-fire attacks give you a decent attack window
• Prioritise Hoppers only if they’re close

Champion versions:

• Black
  • Can’t shoot fires
  • Spawns 1-2 spiders instead of Hoppers
• Red
  • Has a different and significantly harder-to-dodge set of attacks. Projectiles of this attack deal a full heart of damage.
    • Fires a ring of 9 blood shots that spiral outward
    • Fires 4 lines of curving blood shots
    • Fires 4 lines of waving blood shots
    • Fires 10 lines of blood shots in all directions

Appears in:

• Depths, Dank Depths (Boss)
• Womb, Utero (Double Trouble with another Gate)
• Sheol, The Chest, Dark Room (Enemy)

HP: 500
Description: Technically a posthumous version of the Mega Maw, even though the Gate depicts a giant Host.

Attacks & Behavior:

• Behavior
  Stationary. Cycles between three attacks

• Spawn Leaper
  Spawns a Leaper, which lands anywhere in the room

• Brimstone
  Fires a Brimstone laser which connects with all alive Leapers, or other enemies, but doesn’t necessarily connect with the player.

• Blood Shots
  Fires blood shots in either of these three patterns:
  • A ring of 9 projectiles rotating in either direction while spiraling outwards
  • Two rings of 6 projectiles which rotate in different directions while expanding outwards
  • A ring of 11 projectiles in all directions

Tips for the fight:

• Same tips as for Mega Maw; focus on dodging projectiles and attack when the Gate is using their non-projectile attacks
• Stay far away from any Leapers and make sure to stand above the Gate when they’re using their Brimstone attack

Champion versions:

• Black
  • +25% HP (for a total of 625)
  • Flings Big Spiders at the player instead of spawning Leapers
  • Does not perform the Brimstone attack
• Red
  • Has a different, more complex set of attacks
    • Fires 5 lines of slow-moving homing purple shots.
    • Fires 8 lines of blood shots that spiral outwards.
    • Fires 7 lines of blood shots that pulsate outwards.
    • Fires 8 lines of blood shots that move outwards in a zigzag pattern.

Bosses – Peep (2)

This section hosts information for the following bosses

• Peep
• Bloat

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Appears in:

• Chapter II (Boss)
• Womb, Scarred Womb, Sheol, Cathedral, The Chest, Dark Room (Enemy)

HP: 450
Description: Meaty sack of piss. Run ender if you’re either low on health or still on default stats.

Attacks & Behavior:

• Behavior
  Very slowly slides around randomly, cycling between three attacks. At 75% and 25% HP, one of Peep’s eyeballs pop out of their head. These eyeballs move diagonally and are invincible, killed only by Peep’s death.

• Leap
  Leaps into the air and tries to land on the player. Spawns a radial burst of projectiles upon impact

• Radial Burst
  Hops and releases a radial burst of projectiles on impact

• Creep
  Spawns a puddle of yellow creep under themself

Tips for the fight:

• Keep an eye on Peep’s eyeballs. Staying above Peep usually gives the player the least chance to be hit by them

Champion versions:

• Dark Cyan
  • Starts with both eyes popped out
• Yellow
  • -15% size
  • Constantly leaves creep under themself

Appears in:

• Necropolis, Utero (Boss)
• Cathedral, The Chest, Dark Room (Enemy)

HP: 450
Description: Posthumous version of Peep. Slightly harder than the base boss

Attacks & Behavior:

• Behavior
  Spawns along two invincible eyes. These eyes float diagonally and die only when the Bloat dies. Bloat itself slowly slides around randomly, cycling between four attacks

• Brimstone
  If the player is horizontal to the Bloat or below it, the Bloat fires Brimstone lasers either to its sides or below it, depending on the player’s position. The Bloat cannot fire these lasers above themself

• Radial Burst
  Jumps and releases a radial burst of projectiles upon landing

• Creep
  Spawns large puddles of red creep around itself

• Leap
  Leaps into the air and tries to land on the player. Spawns a puddle of creep and sends out a radial burst of projectiles upon impact

Tips for the fight:

• For obvious reasons, do not stay horizontal to, or below the Bloat. Try to stay above them. If this isn’t possible, stay diagonal to them and wait until they leap and relocate themselves to a better position, where you can hit them from above.
• Just like with Peep, keep an eye on the Bloat’s eyeballs

Champion versions:

• Green
  • Fires three Ipecac-like shots instead of their usual radial burst
  • Spawns 1-2 Chargers alongside releasing red creep

Bosses – Polycephalus (3)

This section hosts information for the following bosses:

• Polycephalus
• Stain
• The Pile

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Appears in:

• Catacombs (Boss)
• Caves (Double Trouble)
• Chapter III, Chapter IV, Sheol, The Chest, Dark Room (Enemy)

HP: 200
Description: Burrows underground and jumps out near the player to surprise them. Even then they’re a fairly simple boss

Attacks & Behavior:

• Behavior
  Burrows underground, becoming invincible and after some time also invisible, as the ground sprite becomes gradually smaller the longer Polycephalus is underground. Approaches the player while underground and pops back up when near them before performing any of these four attacks

• Spawn Round Worm
  Spawns a Round Worm

• Projectile Spray
  Fires a Monstro-like projectile spray at the player

• Radial Burst
  Fires 8 projectiles in cardinal and ordinal directions

• Triple Shot
  Fires a wide triple shot at the player

Tips for the fight:

• When Polycephalus goes underground, make sure to stay near them, to ensure that they pop back up before the ground sprite fades away. The last thing you want is a Polycephalus, which could pop up virtually anywhere, even right on you.
• Back up from Polycephalus when they’re about to perform an attack. This gives you moderate time to react.
• A good attack window is when Polycephalus is done with performing their attack and is about to burrow underground
• Prioritise Polycephalus’ spawns over them
• Just two bombs can make quick work of Polycephalus, and when you encounter the Bright Red champion, even a single bomb can make the fight drastically easier

Champion versions:

• Bright Red
  • Spawns in two. Each bright red Polycephalus has 100 HP instead of 200.
  • Cannot spawn Round Worms
• Dark Red
  • Summons Para-Bites instead of Round Worms
  • Every projectile-based attack is replaced by a ring of six projectiles

Appears in:

• Caves, Flooded Caves (Boss)
• Sheol, The Chest, Dark Room (Enemy)

HP: 400
Unlock method: Defeat ??? as three different characters
Description: Posthumous version of Polycephalus. Slightly harder than the base boss

Attacks & Behavior:

• Behavior
  Behavior is identical to Polycephalus’; burrow > pop up near the player and perform attack > repeat. Their attack set is different however

• Spawn Charger
  Spawns two Chargers

• Tendrils
  Whips out its tendrils to their right and left side, spawning creep below them and near Stain themself.

• Projectile Barrage
  Sends out two, spiral-like barrages of projectiles. The first consists of fast-moving bullets which gradually slow down, and the second consists of slow-moving bullets which gradually speed up

Tips for the fight:

• Same strategy as with Polycephalus
• Do not stay horizontal to the Stain to avoid damage from their tendrils

Champion versions:

• Gray
  • Spawns Round Worms instead of Chargers
  • Can’t perform Projectile Barrage

Appears in:

• Necropolis, Ashpit (Boss)
• The Chest, Dark Room (Enemy)

HP: 580
Description: Posthumous version of the Stain. Significantly harder than the Stain

Attacks & Behavior:

• Behavior
  Slowly moves towards the player, cycling between four attacks

• Spawn Bony
  Spawns a Bony

• Spikes
  Spawns lines of spikes in the cardinal directions, starting from the edges of the arena and moving towards the Pile.

• Burrow
  Burrows underground and quickly repositions themself to another random point in the room, indicated by where the ground sprite is moving. Pops back up shortly after and fires a line of 5 projectiles towards the player. The Pile performs this attack 3 times in total before switching to the next one

• Charge
  Charges towards the player, stopping only when met with a wall. Creates two diagonal rock waves away from the wall upon impact along with a spray of projectiles which is aimed towards the player

Tips for the fight:

• Pray to RNGesus that the Pile ends up not performing either Charge or Spikes, as most of the times when the Pile will be performing these attacks you will be in a spot, where it is hard to dodge them.
• Heavily prioritise killing Bonies over damaging the Pile

Bosses – Bumbino

Appears in:

• Chapter II (Boss)
• Cathedral (Enemy)

HP: 385
Description: Bumbo as a boss. An annoying one at that.

Attacks & Behavior:

• Behavior
  Walks towards the player, swiping at any obstacles in the way, destroying them. If there are any coins on the ground, Bumbo prioritises collecting coins over killing the player. Cycles between three attacks. All of Bumbino’s attacks deal a full heart of damage

• Double Swipe
  Swipes once at the player, and then swipes again, but in the opposite direction. After swiping twice, Bumbino smashes the ground, releasing rock waves diagonally and firing rock projectiles in all directions.

• Charge
  If the player is close to the wall and is aligned vertically to Bumbino, they quickly charge at the player and only stop when they hit a wall. Upon impact, Bumbino sends a spray of rock projectiles behind them and rocks start falling from the ceiling. Their landing position is telegraphed by a small shadow that appears for ~1s before the rock falls.

• Butt Bomb
  Rarely launches a butt bomb towards the player

Tips for the fight:

• This fight can go two ways; either you have a build that can melt Bumbino in seconds or Bumbino melts you in seconds. You’re almost guaranteed to get hit at least once in this fight.
• When the rocks start falling down, constantly path to the nearest area without shadows to ensure that no rocks hit you.
• Since Bumbino only uses Charge when they’re vertically aligned to you, you’d think that constantly staying horizontal to them would avoid having to dodge Charge at all if Bumbino can’t perform the attack in the first place, however, Bumbino tries very hard to constantly cycle between his Charge and Double Swipe attacks, meaning that after Double Swipe, Bumbino is going to perform Charge no matter what, and will align themself with the player to do so. Even then, staying horizontal to them is somewhat difficult, considering that obstacles are often present in the arena in large amounts.

Bosses – Reap Creep

Appears in:

• Depths, Dank Depths, Mines (Boss)
• The Chest (Enemy)

HP: 690
Description: A Wall Creep combined with a Blind Creep and a Rage Creep turned into a boss. Relatively hard attack set. Has three phases

Attacks & Behavior (First Phase):

• Behavior
  Spawns in the middle and quickly hops onto the northern wall. Tries to align itself vertically to the player afterwards.

• Spawn Wall Creep
  Spawns a Wall Creep on either the left or right wall

• Projectile Stream
  Fires a continuous stream of projectiles, while trying to align with the player

• Phase 2
  Bringing Reap Creep down to 66% HP triggers Phase 2

Attacks & Behavior (Second Phase):

• Behavior
  Switches to its Blind Creep form and loses all attacks from Phase 1.

• Spawn Enemy
  Spawns either a Trite or 3-4 spiders

• Projectile Spray
  Fires a large, Monstro-like projectile spray

• Projectile Waves
  Fires a few waves of spaced projectiles

• Phase 3
  Bringing Reap Creep down to 33% HP triggers Phase 3

Attacks & Behavior (Third Phase):

• Behavior
  Switches to its Rage Creep form. Loses all attacks from Phase 2

• Brimstone Laser
  Charges up, before firing a brimstone laser in either of these two patterns:
  • One, semi-large brimstone laser aimed at the bottom of the screen. When charging up, and when using the attack itself, Reap Creep tries to align with the player. This attack is telegraphed by a coarse inhale.
  • Four diagonal lasers, 2 on each side, which partially close in on the center. When charging up, and when using the attack itself, Reap Creep tries to align with the player. This attack is telegraphed by a deep “hum”.

• Charge
  Charges to either the left or right side of the screen, causing rocks to fall from above. Their landing position is indicated by a small shadow, ~1,5s before they collide with the ground. Some of these rocks have a chance to be spiders, or Rock Spiders if Reap Creep is fought in the Mines.

Tips for the fight:

• During Phase 1, stay in the middle of the screen to avoid being hit by a newly spawned Wall Creep
• During Reap Creep’s attacks in Phase 2, stay to him aligned horizontally as much as possible. This will either dodge the projectile waves completely or give you tons of room to dodge the projectile spray
• During both Phase 1 and 2, prioritise Reap Creep’s spawns over damaging Reap Creep
• During Phase 3, listen to Reap Creep to know which brimstone attack is coming up. Alternatively, staying horizontal to the Reap Creep can avoid both attacks. However, because the northern side of the arena is always one big pit, you need flight to align yourself horizontally to Reap Creep. Even without flight, you still have a ~20-degree margin of error, so if you can’t align yourself perfectly, you still have a chance of dodging the attack

Bosses – Hornfel

Appears in: Mines (Boss)
HP: 240
Description: Bomb-themed boss. Uses minecarts to move around. Has two phases

Attacks & Behavior (First Phase):

• Behavior
  Spawns in a special boss room, where there are multiple boss room doors connected to each other using rails. Hornfel rides along these tracks while cycling between four attacks. Sometimes Hornfel may enter the arena alongside 2 Fly Bombs. Sometimes an additional minecart enters the arena, which contains either a Fireplace or TNT or an enemy.

• Bombs
  Throws 1-2 bombs at the player. These have a chance to be Hot Bombs or Sad Bombs

• Brimstone Bombs
  Throws three brimstone bombs in random places

• Decoys
  Enters the arena alongside two decoys, which have little to no HP and explode into 6 troll bombs upon death.

• Bomb Flurry
  Accelerates along one set of tracks, rapidly throwing out bombs near himself, before eventually slowing down and puking out a fireball, which spawns lines of fire along the cardinal directions upon impact.

• Phase 2
  Depleting all of Hornfel’s HP triggers Phase 2

Behavior (Second Phase):

• Behavior
  Runs to the nearest boss room door in an attempt to escape. If Hornfel manages to escape, the fight ends

• Death
  If you manage to kill Hornfel before he escapes, he can drop either three bombs, the Brimstone Bombs item, or the Remote Detonator item.

Tips for the fight:

• Hornfel is immune to his own explosions. Player-created explosions still hurt him though
• If the Decoy attack happens right after Brimstone Bombs, the decoys might get unavoidably killed by the Brimstone Bomb lasers, spawning 12 troll bombs
• Enemies inside minecarts almost never attack, so it’s pointless to focus on them
• During Bomb Flurry it’s best to just stay as far away from Hornfel as possible and just wait out the attack
• Prioritise killing any Fly Bombs that may be present

Bosses – Great Gideon

Appears in: Mines, Ashpit (Boss)
HP: 6 waves
Description: Stone grimace on drugs. Summons enemies to fight for them.

Attacks & Behavior:

• Behavior
  Spawns near the northern wall of the room. Spawns six waves of enemies. The player needs to defeat the wave before going onto the next. Great Gideon additionally performs attacks of their own. These include:

• Projectile Bubble
  Spits five projectiles in a cone shape towards the player. The center projectile is significantly bigger and stops mid-trajectory before exploding into 8 projectiles which travel in cardinal and ordinal directions

• Vacuum
  Sucks in all entities and also causes harmful rock projectiles to spawn along the left, right and back walls, which get sucked in as well.

• Furnace
  Heats up and spews out fiery projectiles towards the bottom middle of the screen. Some of these projectiles leave damaging fire behind.

• Special Attack
  Once the 4th wave spawns in, Great Gideon will always create a line of Pit tiles towards the bottom of the screen, which divides the arena into two “rooms”. There will always be one gap in this line, allowing the player to go to the other side if needed.

• Death
  Killing all 6 waves deactivates Great Gideon, ending the fight

Tips for the fight:

• The camera for some reason likes to pan to Great Gideon when they’re using the Vacuum attack. This can easily result in the player getting hit by an unexpected rock. This can be partially remedied by staying at the bottom of the arena.
• If you have a Chaos Card which you do not want to use for any specific final boss, you can use it on Great Gideon to open up a special crawlspace. This crawlspace contains loot in the form of two chests, a single key and two items.
  • Make sure to hit Great Gideon themself with the card, not their spawns.

Bosses – Singe

Appears in: Ashpit (Boss)
HP: 444
Description: Explosion/fart/spike-themed boss. Tough fight if not dealt with fast enough.

Attacks & Behavior:

• Behavior
  Always spawns alongside 4 spiked rocks, which can be knocked about by explosions or physical contact. Slowly walks towards the player and cycles between four attacks

• Charge
  Erratically runs towards the player, before stopping to explode.

• Fart
  Farts, creating explosive gas

• Stagger
  Depleting enough of Singe’s HP triggers this attack. Suddenly stops, before exploding into the air, creating a small circle of pits. Lands back down shortly after somewhere near the player. An additional spiked rock lands along Singe.

• Fiery Fart
  After the second Stagger, Singe can perform this attack. Stands still and farts fire at the player, while also being pushed back. This fire can travel for as much as 4/5 of the horizontal room length

Tips for the fight:

• The spiked rocks can fall into pits, despawning them. However, they come back shortly after whenever Singe performs Charge
  • Only one rock comes back per Charge.
• Explosion-based items like Ipecac, or Dr. Fetus can also knock the spiked rocks around. This can be used to intentionally despawn them, making the fight easier. More often than not though, this combo results in unnecessary damage.
• The spiked rocks can damage Singe if they have enough momentum

Bosses – Loki (2)

This section hosts information for the following bosses:

• Loki
• Lokii

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Appears in:

• Chapter III (Boss)
• Utero (Double Trouble)
• Chapter IV, Sheol, Cathedral, The Chest, Dark Room (Enemy)

HP: 350
Description: Very simple attack set, which may still catch the player off guard sometimes.

Attacks & Behavior:

• Behavior
  Always spawns alongside a single Poky. Floats around randomly and cycles between two attacks. Loki also occasionally teleports to a random place in the room

• Spawn Boom Fly
  Spawns a Boom Fly

• Projectiles
  Fires projectiles in either of these two patterns:
  • 8 projectiles in all directions
  • 4 projectiles in cardinal directions followed by 4 projectiles in ordinal directions and then 4 projectiles in cardinal directions again.

Tips for the fight:

• [none]

Appears in:

• Chapter IV (Boss)
• Utero, Sheol, The Chest, Dark Room (Enemy)

HP: 700
Description: Posthumous version of Loki. Slightly harder than the base boss

Behavior:

• Behavior
  The fight is identical to fighting 2 Loki’s at once. The only difference is that both of the Loki’s spawn Red Boom Flies instead of normal Boom Flies

Tips for the fight:

• Focus on one Lokii at a time

Bosses – Mask of Infamy (2)

This section hosts information for the following bosses:

• Mask of Infamy
• The Visage

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Appears in:

• Necropolis (Boss)
• Dark Room (Enemy)

HP: 350 (150 mask, 200 heart)
Description: Tedious. That’s all. Has two phases

Behavior (First Phase):

• Behavior
  Always spawns alongside its heart. Is invulnerable until the heart is destroyed. The mask turns to the player and chases them at an increased speed if they’re adjacent to the Mask of Infamy in any cardinal direction. Paths directly to the player every time the heart takes damage. The heart can fire 8 shots in all directions if the player is nearby

• Phase 2
  Killing the heart triggers phase 2

Behavior (Second Phase):

• Behavior
  The mask can now be damaged by shooting its eye in its back. The front is still invulnerable though. The behavior of the mask is otherwise the same.

Tips for the fight:

• This fight is extremely tedious without piercing shot, as at most you’ll get one or two shots at the mask before it starts chasing you in Phase 2. More often than not it’s just better to bomb it twice to finish it off quickly

Appears in: Gehenna (Boss)
HP: 620
Description: Gehenna-themed version of the Mask of Infamy. Significantly harder than the base boss. Has three phases

Behavior (First Phase):

• Behavior
  In the first phase, the mask and heart are bound together by a chain, which has 150 HP. This chain also has a fixed length, and extends to only four tiles, however, the mask can temporarily extend the chain and ram into the nearest wall, spawning a burst of rock projectiles, before returning back to the original chain.

• Phase 2
  Killing the chain triggers the second phase

Attacks & Behavior (Second Phase):

• Behavior (Mask)
  Behaves identically to the Mask of Infamy in its second phase. Can be used by the heart to perform certain attacks. The mask can also be deactivated permanently, until Phase 3 begins, if it takes 100 damage.

• Behavior (Heart)
  Avoids the player and occasionally fires a chain towards the mask and performs one of the following four attacks:

• Brimstone Helix
  The heart pulls the mask to itself and causes the mask to fire two brimstone lasers in a double helix pattern. This causes both to get slightly pushed back

• Swing
  Attaches the chain to the mask and swings it around in a spiral while also bringing the two closer. The mask fires purple projectiles outward while being reeled in. If the mask collides with wall before it unites with the heart, it creates rock projectiles on impact
  • The mask will not fire projectiles when it’s deactivated

• Leap
  Pulls the mask in, leaps off-screen and tries to land on the player. Creates diagonal rock waves and a disorganized burst of rocks upon impact.

• Chain
  Swings the chain at the player instead of the heart. If the chain connects, the player is unavoidably brought into the heart, dealing contact damage in the process. If the chain hits a wall, the heart is pulled towards it, creating a burst of rocks and purple projectiles. This attack can only be used when the mask is deactivated

• Phase 3
  Bringing the heart down to 50% HP triggers Phase 3

Attacks & Behavior (Third Phase):

• Behavior
  The heart sheds its outer layer and gains a new set of attacks, while discarding the previous one. Erratically floats around randomly

• Energy Ball
  Spawns an energy ball. These are used in other attacks and can be killed; they have 50 HP. If the mask is deactivated, any energy ball that collides with it will reactivate it, causing it to fire a brimstone laser backwards, which propells it into a wall. The mask spawns a burst of rocks upon contact with the wall. Energy balls which collide with the activated mask still interact with it; causing it to fire another brimstone laser behind itself

• Radial Burst
  Briefly stops and fires a ring of 16 projectiles

• Fiery Radial Burst
  If there are 3 or more energy balls in the arena, the mask deactivates and the mask starts charging up before releasing 4 waves of tightly-packed fires and 4 short-ranged diagonal brimstone lasers. The only way to dodge this attack is to hide behind the mask.

Tips for the fight:

• Deactivating the mask in Phase 2 makes the fight slightly easier. Other than that there’s not much else to say, seriously; you either melt the boss immediately or the boss melts you immediately.

Bosses – The Siren

Appears in: Mausoleum (Boss)
HP: 666
Description: Uses your familiars as an additional way to attack you.

Attacks & Behavior:

• Behavior
  Floats around randomly and cycles between six attacks

• Charm
  Sings, turning the player’s familiars against them. These familiars will start orbiting the Siren.

• Spawn Siren Minion
  If the siren has less than three familiars/orbitals orbiting her, she spawns 3 minions of her own. These minions behave identically to Brother Bobby.

• Familiars
  Glides around, letting her familiars use their effects against the player. After a while, the Siren swings in the direction of the player, releasing her ring of familiars. This ring will explode into a ring of projectiles upon contact with a wall. The amount of projectiles in the ring depends on the amount of familiars killed. The player’s familiars will not be killed and will be returned to the player instead. They will still count towards the projectile ring, however

• Creep
  Sinks into the floor, chasing the player, indicated by the black creep she leaves behind. Reappears shortly after.

• Scream
  Screams and starts emitting a shockwave and spawning nine pulsating rings of projectiles, one after another. The shockwave pushes the player and their projectiles back like an inverted Gaping Maw

• Swipe
  Swipes at the player and additionally fires a 5-shot towards them

Tips for the fight:

• During Charm, more often than not, your familiars will deal immediate contact damage to you when they become charmed. This can be remedied by positioning them correctly. This is not the case for orbitals; they will immediately be teleported to the Siren
• Turn down your volume if you have it high. The screams are ear-wrenching

Bosses – Horny Boys

Appears in: Gehenna (Boss)
HP: 707
Description: Hornfel and Loki fused together. Semi-difficult

Attacks & Behavior:

• Behavior
  Floats around randomly and cycles between five attacks

• Projectiles
  Chains together numerous consecutive tear patterns while gradually increasing the rate in which they are fired. At the end of the attack, Hornfel vomits out three fireballs, which leave fire lines in cardinal directions

• Brimstone Bombs
  Teleports, while throwing short-fused Brimstone Bombs. In total, the Horny Boys teleport 3 times.

• Sad Bombs
  Throws Sad Bombs at their feet to create a smokescreen, before teleporting to another location and repeating the attack. In total, the attack is performed 5 times
  • The Sad Bombs work normally, and spawn a radial burst of 8 projectiles in all directions

• Triple Bomb
  Juggles three bombs and fires them at the player shortly after. These bombs have a chance to be Hot Bombs or Sad Bombs

• Spawn Boom Fly
  Spawns a Boom Fly accompanied by three Eternal Fly Bombs orbiting it.

Tips for the fight:

• [none]

Bosses – Blastocyst

Appears in:

• Womb, Scarred Womb (Boss)
• Chapters I-IV (Enemy, in small form)
• Chapter IV, The Chest, Dark Room (Enemy, in medium form)
• Sheol, The Chest, Dark Room (Enemy)

HP: 460 in total (Large form has 190 HP, medium form has 75, small forms have 30. There is 1 large form, 2 medium forms and 4 small forms in total)
Description: Only the large form is a somewhat difficult boss. The rest is a cakewalk.

Attacks & Behavior (Large Form):

• Behavior
  Stands still and occasionally hops towards the player. Cycles between two attacks

• Hop
  Hops, creating a disorganized burst of projecitles around themself

• Leap
  Leaps and tries to land on the player. Upon impact, creates a radial burst of 8 projectiles which travel in all directions

• Medium Form
  Killing the large Blastocyst makes it split into two medium copies of itself

Behavior (Medium Form):

• Behavior
  Hops around aimlessly and sometimes spawns a hexagonal burst of projectiles upon impact

Behavior (Small Form):

• Behavior
  Hops around aimlessly and sometimes fires 4 shots in cardinal directions

• Death
  When the small form killed, an Embryo enemy is left behind

Tips for the fight:

• Once you kill the large form, you basically won the fight

Bosses – Daddy Long Legs (2)

This section hosts information for the following bosses:

• Daddy Long Legs
• Triachnid

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Appears in:

• Utero (Boss)
• Cathedral, The Chest, Dark Room (Enemy)

HP: 500
Description: A literal giant enemy spider. Mainly uses their legs to attack the player

Attacks & Behavior:

• Behavior
  Stationary. Cycles between three attacks

• Stomp
  Stomps the player 4 (occasionally five) times, before slamming down in the vertical middle of the screen, firing out 8 shots in all directions

• Quick Stomp
  Stomps 4 times at random locations. One of these is guaranteed to be near the player

• Spawn Spider
  Spawns 2-3 Spiders

Tips for the fight:

• During Stomp, do not stand in the vertical middle of the screen. Otherwise you’ll take unavoidable damage when Daddy Long Legs slams down

Appears in: Utero, Scarred Womb (Boss)
HP: 500
Unlock method: Defeat Isaac 10 times
Description: Alternate version of Daddy Long Legs. Slightly easier than the base boss

Attacks & Behavior:

• Attacks & Behavior
  Behavior of Triachnid is identical to that of Daddy Long Legs, except Triachnid uses only three limbs at a time, and each of his attacks spawn slowing, white creep. Triachnid also spawns a single Trite instead of spiders

Tips for the fight:

• Same as Daddy Long Legs; during Stomp, do not stand in the vertical middle of the screen. Otherwise you’ll take unavoidable damage when Triachnid slams down

Bosses – Mr. Fred

Appears in: Womb, Scarred Womb (Boss)
HP: 500
Description: Boss version of the Fred enemy. Extremely easy.

Attacks & Behavior:

• Behavior
  Stationary. Stays in the middle of the room and cycles between three attacks. He also spawns alongside 4 Homunculi. He can release them at any time.

• Spawn Fred
  Spawns a Fred

• Burrow
  Burrows into the ground and reappears shortly after, releasing 8 shots in all directions

• Creep Shot
  Fires out four large projectiles in cardinal directions, which leave creep behind themself. They leave a bigger puddle of creep upon contact with the ground

Tips for the fight:

• The Homunculi that accompany Mr. Fred cannot release themself, and are only released under Mr. Fred’s command

Bosses – Rotgut, Chimera, The Scourge

This section hosts information for all of the corpse bosses: Rotgut, Chimera, and the Scourge

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Appears in: Corpse I (Boss)
HP: 1800
Description: A boss so complex you might as well classify it as a final boss. If you encounter them, say goodbye to your run. Has three phases

Behavior (First Phase):

• Behavior
  Stationary. Sits in the middle of the room and spews projectiles and enemies everywhere.

• Phase 2
  Killing the first phase forces Rotgut to suck the player inside themself. This triggers Phase 2

Attacks & Behavior (Second Phase):

• Behavior
  The player jumps into Rotgut and enters a crawl space-like interior, with a maggot sitting on the right. The interior consists of two floors: the platform, and the floor. The maggot’s attacks are the following:

• Brimstone Laser
  Fires a brimstone laser which covers the entire floor of the room

• Bomb
  Spits out a projectile, which lands on the platform. Upon contact, this projectile splits into multiple arcing projectiles

• Vomit
  Charges up before vomiting projectiles, Attack Flies and Maggots towards the floor.

• Waving Shots
  Spews out a couple of projectiles moving in a wave pattern. These projectiles cover both the platform and the floor

• Gas & Projectiles
  Spews out projectiles and toxic gas towards the platform

• Phase 3
  Killing the maggot lets the player enter the heart chamber, where Phase 3 begins

Behavior (Third Phase):

• Behavior
  Sits at the top middle of the screen, similar to Mom’s Heart or It Lives. Each pulse of the heart releases a ring of projectiles. The other attacks are so complex and undodgeable that it’s not even worth it to describe them.

Tips for the fight:

• Either you melt the boss instantly or you die instantly, there’s no other fucking tip. This boss is impossible

Appears in: Corpse I (Boss)
HP: 950
Description: Similar in difficulty to Rotgut. Their lower HP makes them an easier fight than Rotgut, even though both are impossible anyway

Attacks & Behavior:

• nope, i’m done, i’m fucking done– i spawn him in, take a look at his attacks and immediately decide that whoever was designing this sodding piece of shit was on some HEAVY drugs. i am not going to waste my precious time on describing each of his attacks in detail because 3/4 of them are impossible to dodge anyway. i’m done. fuck the scourge, fuck this game, fuck my life, fuck everything. the fact that i’m even writing this instead of following protocol just shows how bullshit this boss is.

Tips for the fight:

• 🙂

Appears in: Corpse I (Boss)
HP: 545
Description: Unlike the other two, this one can actually be dodged consistently. Has two phases

Attacks & Behavior (First Phase):

• Behavior
  Chases the player while performing any of these four attacks:

• Spawn Maggots
  Spawns 5 small Maggots

• Spawn Sick Boom Fly
  Spits out a Sick Boom Fly and slaps it towards the player

• Jump
  Jumps twice towards the player. During the first jump, Chimera fires out 8 projectiles in all directions upon impact, and during the second jump, they release rock waves in all diagonal directions

• Vomit
  Vomits out 8 Ipecac-like projectiles towards the player’s position. Landing positions are marked

• Phase 2
  Bringing Chimera down to roughly 50% HP triggers Phase 2

Attacks & Behavior (Second Phase):

• Behavior
  Chimera performs one last charge before tripping, which divides the head and body into separate entities. Both have a unique set of attacks

• Attacks & Behavior (Body)
  • Chases the player while occasionally peforming any of the attacks below
  • Fires a brimstone laser downwards, which propells it into a wall
  • Runs towards the player and starts rolling around
  • If the head dies first, it starts endlessly rolling around

• Attacks & Behavior (Head)
  • The head slides around aimlessly while performing any of the attacks below
  • Fires 4 waves of 5 lines of projectiles at the player
  • Dashes three times towards the player. The third dash is always aimed towards the body, which picks up the head and throws it towards the player. The head during this will leave projectiles behind itself and will spawn a disorganized burst of projectiles upon collision with a wall
  • If the body dies first, the head will continuously perform long charges towards the player

Tips for the fight:

• Focus on Chimera’s spawns during Phase 1; they become a real nuisance if not dealt with quickly
• Staying far away from the head during Phase 2 gives you more reaction time to dodge the projectile attack it rarely performs

Bosses – Dogma

Unlike what you’d think, Dogma, by the game’s definition at least, is NOT a final boss, mostly because they don’t have their own completion mark, but also because their relatively low health and simple attack set would not classify them as a final boss anyway, even if they’re a part of the Beast fight.
The Ultra Harbingers will be listed inside of the Beast’s final boss section.

HP: 2400
Armor: 30
Description: Dogma is the first boss out of 6, which the player fights in the Home floor. They are Isaac’s portrayal of the christian broadcasts he used to watch with his mother. Has two phases

Attacks & Behavior (First Phase):

• Behavior
  Dogma is tethered to the TV, which protects him from damage. This TV needs to be destroyed to allow the player to hit Dogma. Damaging creep actively appears under Dogma throughout the entirety of Phase 1

• Aura Tears
  Dogma will fire 3-4 waves of godhead-like tears. Staying in their aura for too long damages the player

• Tear Burst
  Dogma will fire 4 consecutive bursts of tears, each one containing more tears than the previous one. When below 60% health, Dogma will sometimes stop the tears mid-flight, leaving them to float in place. This variation occurs more often the less health Dogma has

• Laser Tears
  Dogma will fire 3-4 waves of a random arrangement of tears, which spawn harmless beams upon landing. After a while, damaging lasers spawn in place of these beams.

• Static Brimstone
  Dogma will fire a brimstone beam in the closest cardinal direction to the player. This beam actively bends towards the player, and will switch sides if the player moves too far away from it. The laser can switch only 3-4 times

• Phase 2
  Destroying the TV triggers the second phase

Attacks & Behavior (Second Phase):

• Behavior
  Upon destroying the TV, Dogma falls into the ground and reappears shortly after as an orb, which grows a pair of wings. This new form will slowly float towards the player.

• Feather Spread
  Dogma will gather their wings together and fire a spread of feathers towards the player. This is usually the first attack that Dogma performs

• Orb of Light
  Dogma will create a ball of light over their head. Harmless beams of light protrude from this ball, which then stop and become damaging lasers. This attack repeats 3 times in total before Dogma throws the ball towards the player which does the same attack, albeit with a smaller amount of beams. Dogma will not attack until the ball and its’ beams have disappeared.

• Ophanim
  Dogma shapeshifts into a winged wheel and flies out of the screen. Shortly after Dogma charges towards the player from the same direction they disappeared from, simultaneously firing 3 layers of 12 feathers. Dogma will charge the player 6 times in total before the attack is over.

• Death
  Depleting Dogma’s health kills them, gives the player the Dogma item, and triggers the Beast fight

Tips for the fight:

• The player spawns extremely close to Dogma, and not moving or moving up always results in the player being damaged. To avoid this, instantly move down to get away from Dogma before he deals contact damage to the player.
• The only really difficult attack the first phase has is the brimstone beam, which can still be dodged consistently with practice. The best way to dodge this attack is to stay diagonal to Dogma, and trying to get the laser to switch as many times as possible
• The player has to stand for a decently long time inside the tear aura to actually get hit, meaning you get tons of room for error during this attack. Just make sure not to hit the tear itself
• Staying far away from Dogma allows for more reaction time
• When Dogma enters their second phase, the player can put a bomb near them when they appear as an orb, the bomb doesn’t make much of a difference but it’s at least something.
• The only breather you get during the second phase is the ball of light attack, which is usually easy to avoid and pretty slow-paced.
• Running around in circles during the Ophanim attack is usually surprisingly effective, just make sure not to hit the feathers. Try to put as much distance between you and Dogma before he releases the 3 layers of feathers.
• The feather spread can catch you off guard, keep your distance
• A useful attribute to have in this fight is speed. 1.50-2.00 speed is optimal, while anything below 1.00 can sometimes result in unavoidable damage

Bosses – Universal

This section hosts information for the following bosses:

• The Fallen
• Headless Horseman

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Appears in:

• Anywhere from Basement II to Womb I if the player has entered the premises of a devil room (Boss)
• Sheol, The Chest, Dark Room (Enemy)

HP: 60
Stage HP: 45
Description: It’s always a pleasant surprise to find this boss. Has two phases

Attacks & Behavior (First Phase):

• Behavior
  Flies aimlessly and peforms 2 attacks

• Projectile Spread
  Fires a spread of three shots, and then four shots towards the player

• Charge
  Starts chasing the player at an increased speed. Once the Fallen takes enough damage, they fire 4 Brimstone lasers in all cardinal directions

• Phase 2
  At 50% HP, the Fallen enters its second phase

Behavior (Second Phase):

• Behavior
  Splits into two copies of itself. These copies have an identical AI to The Fallen in Phase 1

• Death
  Upon death, the Fallen drops an item from the Devil Room item pool instead of the Boss Room pool.

Tips for the fight:

• Focus on one Fallen at once in Phase 2

Appears in:

• Anywhere from Basement II to Womb I (Boss)
• Necropolis (Enemy, only head)
• Sheol, Cathedral, The Chest, Dark Room (Enemy)

HP: 160
Stage HP: 30
Description: It’s always an unpleasant surprise to find this boss. Exists as two separate entities

Behavior:

• Behavior
  Spawns as two separate entities, the head and the body. The head can either shoot a triple shot towards the player or start charging, wrapping around the screen three times before stopping, while the body only shoots Ipecac-like projectiles towards the player, which leave a big puddle of creep upon impact

• Death
  The Headless Horseman always drops the Pony item upon death instead of a Boss Room pool item.

Tips for the fight:

• Focus on the head first; its triple shot is extremely annoying

Boss Rush

Boss Rush is a special optional area located in Chapter III and its alternate versions (including Mausoleum and Gehenna).

It can be accessed only after beating Mom in under 20 minutes (25 in Mausoleum/Gehenna).
Doing so will spawn the door leading to the room. This door will despawn upon exiting the room if the in-game timer goes past 20/25 minutes.

The room itself is a 2×2 room, containing either 2, 4 or 8 items inside, which the player can choose from. Picking up an item despawns the others and triggers the Boss Rush.

The Boss Rush consists of 15 waves, each of which spawns two random bosses that the player needs to fight to proceed to the next wave. The bosses are pulled from Chapters I-III, with a few from Chapter IV as well.

Killing the 15th wave will end the Boss Rush, spawning an additional item as a reward.

The Boss Rush counts as a completion mark, meaning the player will have to complete it with each character in order to 100% the game. Once that’s done though, the player can still use the Boss Rush to their advantage by teleporting out of the room after picking up an item. This is made easier with the guaranteed marked skull in Depths II once the Strange Door has been unlocked.

This method does give you just one item instead of the usual two you’d get from fighting Boss Rush normally, but it beats fighting through 30 bosses, risking your run in the process, especially if your run isn’t suited for such a challenge yet.

Final Bosses – Introduction

Final Bosses are super-strong class bosses, which have special attack patterns, a lot of health, and usually end, or choose the path of your run

In TBoI: Rebirth there are 12 final bosses, with 2 of them being in Greed Mode

Final Bosses – Mom

Appears in: Second floor of Chapter III, regardless of the floor version.
HP: 645
Phases: 1

Arena, Attacks & Behavior:

• Arena
  Mom’s arena has 4 boss room doors in the middle of each wall. Mom can use these doors to perform attacks

• Behavior
  Upon spawing, always stomps once in the middle of the room. Exists off-screen and comes on-screen to perform any of these attacks:

• Stomp
  Grunts before stomping the player with her foot. A giant shadow under the player also telegraphs the stomp
  • The foot deals contact damage even after the stomp

• Flesh
  A bit of Mom’s skin peeps out of the door and spawns a random low-tier monster

• Eye
  One of mom’s eyes peeps out of the door. The eyes are harmless except for their contact damage.

• Hand
  If the player is near any door, one of Mom’s hands rushes out of the door in an attempt to deal contact damage to the player

• Death
  Upon death, Mom:
  • Kills all enemies in the room (except for Globins, which get turned into goo)
  • Drops The Polaroid and/or the Negative items (if unlocked)
    • If the Polaroid or the Negative are not unlocked, Mom will drop an item from the Boss Room item pool
  • Has a 5% chance to spawn the Void gateway (if unlocked) if the player has >20 items or >10 damage.
  • Triggers the Epilogue ending cutscene if she is defeated for the first time

Tips for the fight:

• The player is permanently trapped inside the room, even after Mom has been killed. Make sure that you’re done with everything on the floor before fighting Mom
  • The player can still get out by teleporting, via items such as tarot cards (The Fool, The Hermit, The Moon, The Stars), pills (Telepills effect) or active or even passive items (Teleport, Cursed Eye (charge the shot and bomb yourself while the shot is still charging) etc.)
• If possible, move in a small circle around the middle, to have the best chance of avoiding the stomp while also not risking being hit by the hand. Alternatively, you can stand in a corner, where there’s no obstacles and wait for Mom to stomp there
• Prioritise killing any chaser-type enemies over damaging Mom

Champion versions:

• Blue
  • +23% HP (for a total of 793.4 HP)
  • Spawns different enemies from her normal version, these are:
    • Trites
    • Spiders
    • Big Spiders
    • Buttlicker
    • Keeper
• Red
  • More aggressive AI: doesn’t spawn enemies, uses her hands more often, her eyes shoot a triple shot upon spawning, stomps significantly more often

Alternate path version:
Mom has a special, stronger version of herself, which appears in Mausoleum II or Gehenna II.
The differences between the two versions are:

• Alt Mom can perform a triple-stomp, where she stomps the player three times in quick succession, with the third stomp releasing explosions in cardinal directions
• Alt Mom’s eyes fire brimstone lasers in a double helix pattern if the player is in their line of sight
• The enemies Alt Mom spawns are significantly stronger than default Mom’s. These include:
  • Cursed Globins
  • Fetal Demons
  • Rag Man’s Raglings
  • Suckers
  • Attack Flies
  • Psychic Horfs
• Alt Mom cannot use her hands, unlike default Mom

Final Bosses – Mom’s Heart

Appears in: Second floor of Chapter IV (except for the Corpse), or in Mausoleum II/Gehenna II
HP: 950
Unlock method: Kill Mom
Phases: 3

Arena, Attacks & Behavior (First Phase):

• Arena
  As opposed to Mom, Mom’s Heart’s arena is a normal boss arena. The player always spawns on the middle bottom of the arena, regardless of the door position

• Behavior
  Sits in the top middle of the arena. Spawns accompanied by two eyes. Killing each eye spawns another one in its place at the top of the screen. When fighting the eyes, Mom’s Heart will retreat upwards and fire a pattern of 4 slow projectile lines, which slowly rotate clockwise. Mom’s Heart is invulnerable when she’s in the ceiling. When the second set has been killed, Mom’s Heart alternates between two states

• Projectile State
  Fires projectiles in various patterns, these include:
  • 10 projectiles in all directions that expand outwards either continuously or in a pulsating manner
  • 3 pulsating curved lines of projectiles that rotate and expand outwards
  • 2 rings of ten projectiles that pulsate outwards at different intervals
  • A single, continuous line of projectiles that follows the player
  • 8 slightly curved lines of projectiles that rotate and expand outwards
  • 5 lines of projectiles that mimic the player’s movements
  • 4 curved lines of projectiles that continuously rotate and expand outwards.

• Summon State
  Mom’s Heart spawns two enemies of a singular type and stops performing her special projectile attacks shortly after, before retreating to the ceiling and firing the four projectile lines. Killing the enemies is required to progress, and doing so will revert Mom’s Heart to the projectile state. Just like with the Eyes, the enemies spawned by Mom’s Heart are replaced once by another one after they have been killed.

• Phase 2
  Bringing Mom’s Heart down to 60% HP triggers Phase 2

Behavior (Second Phase):

• Behavior
  Mom’s Heart cannot retreat to the ceiling anymore and constantly performs her projectile attacks along with occasionally spawning two enemies of the same type

• Phase 3
  Bringing Mom’s Heart down to 10% HP triggers Phase 3

Behavior (Third Phase):

• Behavior
  Mom’s Heart abandons all of her previous attacks and fires 4 diagonal brimstone lasers, which rotate either clockwise or counter-clockwise shortly after.

• Death
  Upon death, Mom’s Heart fires out a ring of 14 projectiles and also:
  • Spawns the End Chest
  • Has a 10% chance to spawn the Void gateway (if unlocked)

Tips for the fight:

• High range helps you deal with the Eyes at the beginning of the fight. If you have items like Technology, you can take care of the two side Eyes, and then rush to the top of the screen to quickly kill the two replacements.
• A single bomb can kill Mom’s Heart in any point of time in Phase 3, essentially evading the whole phase altogether

Alternate path version:
Mom’s Heart has a special, stronger version of herself, which appears in Mausoleum II or Gehenna II. To access her, the player needs to complete the Repentance puzzle and open the door leading to her chamber, which appears after defeating Alt Mom. Alt Mom’s Heart has completely different, and much more complex behavior:

• The player needs to kill only two Eyes instead of four.
• Alt Mom’s Heart never retreats to the ceiling except when fighting the Eyes
• Alt Mom’s Heart never summons enemies and is permanently in the projectile state. Her attacks are different from normal Mom’s Hearts. They are the following:
  • 2 interwined rings of 8 projectiles that expand outwards at different speeds.
  • 2 lines of projectiles that rotate and expand outwards in a spiral motion.
  • 5 lines of projectiles that rotate and pulsate outwards.
  • A ring of 12 projectiles that expands outwards, along with 2 rings of 4 projectiles that expand outwards and rotate in opposite directions at a higher speed.
  • 2 rings of 8 projectiles that expand outwards and rotate in opossite directions, creating curved lines that encase certain areas.

Upon death, Alt Mom’s Heart fires the 14-projectile ring, and opens the passageway to the Corpse. This passageway is in the room, in which the player fought Alt Mom

Final Bosses – It Lives!

Appears in: Second floor of Chapter IV (except for the Corpse).
Unlock method: Kill Mom’s Heart 11 times
HP: 950
Phases: 3
Permanently replaces Mom’s Heart in Chapter IV (except for the Corpse) once unlocked

Behavior:

• Behavior
  Behavior is near-identical to Mom’s Heart with a few exceptions:
  • Spawns Knights instead of Swingers, and has a chance to spawn a boss instead of enemies.
    • It Lives can spawn either Chub, Teratoma, Fistula or Polycephalus
  • Shoots one set of double projectiles when retreating upwards after spawning enemies/bosses

• Death
  Upon death, It Lives:
  • Fires out a ring of 14 projectiles
  • Opens the gateway to ??? if it has been killed in under 30 minutes
  • Opens the gateways to Sheol and Cathedral
  • Has a 10% chance to open the gateway to the Void (if unlocked)

Tips for the fight:

• Tips for Mom’s Heart also apply for this boss

Final Bosses – Hush

Appears in: ???
HP: 6666 (7666 if counting the first form)
Unlock method: Defeat Mom’s Heart 10 times
Phases: 8 (3 in first form, 5 in true form)

Arena, Attacks & Behavior (First Form):

• Arena
  Standard 2×2 arena.

• Behavior
  Behaves identically to ???, albeit with 1000 HP instead of 2000 and longer projectile range

• True Form
  Killing the first phase spawns the true form of Hush

Attacks & Behavior (First Phase):

• Behavior
  Emerges from the top middle of the room. Performs 1 attack

• Bullet Hell
  Fires barrages of glowing projectiles in certain patterns, combining 1-3 different patterns of projectiles. These patterns include:
  • Rings of projectiles that alternate between rotating clockwise and counterclockwise as they move outwards.
  • U-shaped salvos aimed at the player.
  • Lines of projectiles aimed at the player that either gain (yellow), lose (blue), or maintain (green) momentum as they travel (these lines have spaces between them every 4-5 shots).
  • 2-4 repeating volleys of 4 projectiles, with equal spacing between each volley (the angle these volleys are shot out at rotates as the attack continues).

• Phase 2
  Hush enters the second phase when brought down to 80% HP

Attacks & Behavior (Second Phase):

• Behavior
  Sinks into the ground, becoming invulnerable. Reemerges after a few seconds and relocates to the middle of the room. Hush retains all attacks from Phase 1 and gain a new one. Its Bullet Hell attack also gains two new patterns, these are:
  • A very dense ring of projectiles with a single gap, aimed towards the player’s general direction
  • 3-5 spirals of projectiles, with even spacing between each spiral

• Hush Flies
  Spawns a swarm of Hush Flies, which either orbit Hush, fly in the direction the player was in when they spawned, or chase the player.
  • These flies have a short invincibility window. This period lasts for ~5s

• Phase 3
  Hush enters the third phase when brought down to 60% HP

Attacks & Behavior (Third Phase):

• Behavior
  Retains all attacks from the previous phases. Gains two more attacks and the Bullet Hell attack gains one more pattern:
  • A very wide spread of projectiles that closes in on where the player was standing when fired.

• Hush Gapers
  Spawns a large amount of Blue Gapers before sinking into the ground to relocate. Hush can rarely spawn Blue Boils while relocating

• Continuum
  Fires three wavy lines of Continuum shots in one of the four cardinal directions. These shots wrap around the screen once while constantly accelerating. Hush performs this attack 2-5 times in a row before moving onto the next one

• Phase 4
  Hush enters the fourth phase when brought down to 40% HP

Attacks & Behavior (Fourth Phase):

• Behavior
  Gains two new attacks. Attack cooldown is significantly reduced

• Panic Bullet Hell
  Hush sinks into the ground and either moves aimlessly or chases the player, while performing the Bullet Hell attack and occasionally spawning Blue Boils. The Panic Bullet Hell can only use patterns from Phase 1 of the true form.

• Splitters
  Hush fires out three, large projectiles. These projectiles split multiple times into three smaller copies of themself. This attack usually covers 2/3 of the arena in projectiles. Hush can, and will usually perform other attack before the projectiles from this attack disappear.

• Phase 5
  Hush enters the fifth phase when brought down to 20% HP

Attacks & Behavior (Fifth Phase):

• Behavior
  Can’t perform Hush Flies anymore. Retains all other attacks from the previous phases and gains one more attack

• Lasers
  Fires two lasers into the air, which come back down shortly after and start chasing the player at rapid speeds. These lasers also leave behind slidy creep. While firing the lasers, Hush will also fire out five, wavy projectile lines.

• Death
  Upon death, Hush:
  • Kills all projectile entities and enemies
  • Drops the End Chest if killed for the first time
  • Opens the gateways to Sheol, Cathedral and the Void on subsequent kills

Tips for the fight:

• An Era Walk rard or the I’m Drowsy pill effect help a lot during this fight. Keep in mind that I’m Drowsy will make it impossible to dodge the laser attack, since the laser speed is based off the player’s unmodified speed
• Try to kill Hush ASAP after they reach 40% HP. Hush in this state can perform some nasty combos, which will usually result in unavoidable damage

Final Bosses – Satan

Appears in: Sheol
HP: 1200
Phases: 3

Arena & Behavior (First Phase):

• Arena
  Standard 1×1 arena

• Behavior
  Satan himself appears as a devil statue. 4 seconds after entering the boss room, The Fallen spawns below the statue, accompanied by 2 Kamikaze Leeches.

• Phase 2
  Killing all of the enemies awakens Satan and triggers Phase 2

Attacks & Behavior (Second Phase):

• Behavior
  The aforementioned statue turns into Satan’s second phase. This new form tries to stay in the middle of the screen and performs three attacks

• Half Rings
  Fires half-rings of 8 projectiles out of both of his hands

• Projectiles
  Fires a spread of 5, then 4 projectiles at the player

• Brimstone
  If the player is below Satan, he can fire a Brimstone laser in either of these patterns:
  • One laser directly downwards from his mouth
  • Two lasers from both of their hands, which partially close in on the center

• Phase 3
  Depleting Satan’s HP triggers the third phase

Behavior (Third Phase):

• Behavior
  Satan flies off-screen and tries to stomp the player using both of their hooves. The stomps happen one after another, and both hooves are retracted when both have stomped. Kamikaze Leeches spawn at random intervals during this phase.

• Death
  Upon death, Satan:
  • Kills all existing Kamikaze Leeches
  • Drops the End Chest (which serves as a gateway to the Dark Room, if the player has the Negative)
  • Has a small chance to spawn the portal to the Void

Tips for the fight:

• Placing a bomb under the statue right before the Fallen spawns eliminates both of the Kamikaze Leeches and in most cases skips the first phase of the Fallen entirely
• Constantly baiting Satan into using his brimstone attack makes the fight trivial
• Prioritise Kamikaze Leeches in Phase 3

Final Bosses – Isaac

Appears in: Cathedral
HP: 2000
Phases: 3

Arena, Attacks & Behavior (First Phase):

• Arena
  Standard 1×1 arena

• Behavior
  Stationary. Lies in the middle of the room and doesn’t attack until damage is dealt to him. After any amount of damage has been dealt, Isaac starts attacking the player

• Projectiles
  Fires projectiles in either of these patterns:
  • 10 lines of projectiles in every direction.
  • 8 groups of projectiles in a that curve back towards him.
  • 8 groups of long-range spinning projectiles along with 10 slightly curved lines of shorter-range projectiles in every direction.

• Phase 2
  Isaac enters his second phase when brought down to 66% HP

Attacks & Behavior (Second Phase):

• Behavior
  Stationary. Isaac stands up and gains a new set of attacks, discarding the old one

• Projectiles
  Fires projectiles in either of these two patterns:
  • Shoots 4 projectiles in a cross pattern, which splits into four short-ranged projectiles after a short time, similar to the Cricket’s Body item.
  • Shoots 8 projectiles in all directions.

• Light
  Summons two beams of light, both in random locations

• Spawn Angelic Baby
  Spawns two Angelic Babies below himself

• Phase 3
  Isaac enters his third phase when brought down to 33% HP

Attacks & Behavior (Third Phase):

• Behavior
  Isaac grows a pair of wings and is no longer stationary. Erratically chases the player and cycles between two attacks

• Projectiles
  Fires projectiles in either of the Phase 1 patterns

• Light Barrage
  Teleports off-screen and summons light beams to cover the screen, starting from one of the top corners to the opposite bottom corner. Isaac always performs this attack at the start of this phase and repeats this process every time he takes a certain amount of damage.

• Death
  Upon death, Isaac:
  • Drops the End Chest (which serves as a gateway to the The Chest, if the player has the Polaroid)
  • Has a chance to open up the portal to the Void

Tips for the fight:

• Isaac’s projectile attacks make it hard to get close to him, or even cardinal to him. Items, which block projectiles are extremely helpful in this fight
• Because Isaac does not attack the player until he takes damage, you can set up a powerful first hit (i.e. using the Remote Detonator to circle Isaac with bombs, and then using it to blow all of them up at once), assuming you don’t have any familiars, which may hit Isaac regardless of whether you want it or not
• If possible, speed through Isaac’s first and second phases, as they can get really hectic if not dealt with quickly

Final Bosses – ???

Appears in: The Chest
HP: 2000
Phases: 3

Arena, Attacks & Behavior (First Phase):

• Arena
  Standard 1×1 arena

• Behavior
  Just like Isaac, ??? lies in the middle of the room, refraining from attacking the player until he himself receives damage. After ??? takes any amount of damage, he starts attacking the player. ??? regardless of current phase:
  • Will fire occasionally projectiles directly towards the player
  • Will have a chance for a few of his projectiles to be homing

• Projectiles
  Fires projectiles in either of these two patterns:
  • Shoots 7-8 rapid-fire lines of projectiles in all directions that expand outwards. After taking enough damage, these lines curve while travelling.
  • Shoots 8 lines of 2 projectiles in all directions that expand outwards. Each line consists of one normal projectile and one homing projectile. After taking enough damage, these lines curve while travelling.

• Spawn Random Fly
  Spawns either an Attack Fly, a Moter or a Pooter to orbit ???
  • The pooters shoot immediately after spawning

• Phase 2
  ??? enters his second phase when brought down to 66% HP

Attacks & Behavior (Second Phase):

• Behavior
  Still stationary. Stands up and gains a new attack set, but doesn’t lose the ability to spawn flies. 2 Eternal Flies start orbiting ???, partially blocking incoming shots

• Projectiles
  Fires homing projectiles in either of these two patterns:
  • 4 projectiles in an offset X pattern.
  • 8 projectiles in all directions.

• Phase 3
  ??? enters his third phase when brought down to 33% HP

Behavior (Third Phase):

• Behavior
  ??? grows a pair of wings and starts slowly hovering towards the player while firing projectile patterns from Phase 1. ??? also spawns flies more frequently and can teleport near the player.

• Death
  Upon death, ???:
  • Drops the End Chest
  • Has a chance to spawn the portal leading to the Void

Tips for the fight:

• Tips for Isaac also apply for this boss

Final Bosses – The Lamb

Appears in: Dark Room
HP: 2600
Phases: 2

Arena, Attacks & Behavior (First Phase):

• Arena
  Standard 1×1 arena

• Behavior
  Floats towards the player and performs three attacks. Attack Flies may rarely spawn when the Lamb is performing their attacks.

• Projectiles
  Fires projectiles in any of these three patterns:
  • 6 rings of 10 projectiles outwards with one projectile always aimed in the player’s direction. The Lamb continues to move towards the player at a very slow pace while performing this attack
  • Rotating waves of 3 projectiles in a around itself in all directions that split apart once they make contact with any surface, similar to the Cricket’s Body item
  • 5 rotating lines of projectiles.

• Homing Projectiles
  Fires 2-4 lines of homing projectiles in a spread, that rotate to follow the player’s movements.

• Explosive Projectiles
  Fires small, Ipecac-like projectiles around itself. The Lamb usually begins the fight with this attack

• Phase 2
  Bringing the Lamb down to 50% HP triggers Phase 2

Attacks & Behavior (Second Phase):

• Behavior
  Splits into two entities: the head, and the body. Both have unique attack sets, and both need to be killed to end the fight

• Attacks & Behavior (Head):
  • Floats towards the player and performs any of the attacks below:
  • Charges extremely fast towards the player, stopping at the edge of the room.
  • Performs any projectile attack from Phase 1
  • Fires four Brimstone beams in the cardinal directions. The beams can rarely rotate 90 degrees either clockwise or counterclockwise.
  • Fires a large burst of homing projectiles towards the player

• Attacks & Behavior (Body):
  • Stationary
  • Fires a large burst of disorganized projectiles in all directions and spawns up to 5 Attack Flies
  • Creates a temporary Curse of Darkness effect upon death

• Death
  Upon death, The Lamb:
  • Drops the End Chest
  • Has a chance to spawn the portal leading to the Void

Tips for the fight:

• This boss can be quite hectic, make sure to kill it fast.
• Projectile-blocking items help a lot in this fight

Final Bosses – Mega Satan

Appears in: The Chest Golden Door/Dark Room Golden Door
HP: 5000
Armor: 90
Phases: 2

Arena, Attacks & Behavior (First Phase):

• Arena
  Standard 1×2 arena, with the upper 1/3 inaccessible. Contains a pentagram in the middle, which the player needs to step on to spawn Mega Satan

• Behavior
  When spawned, Mega Satan sits in the inaccessible part of the room, accompanied by his two hands. Performs 5 attacks

• Projectiles
  Closes his eyes, and fires projectiles in either of these patterns:
  • 3-5 lines of blood projectiles. The angle these shots are fired at alternates between rotating clockwise and counterclockwise. The less lines of projectiles there are, the faster they travel and rotate.
  • Spreads of brown projectiles that split into 4 smaller projectiles after traveling far enough, similarly to the Cricket’s Body item.
  • 2 spirals of blood projectiles that very rapidly rotate clockwise, creating semi-circular waves of projectiles.
  • Rings of blood projectiles, fired in rapid bursts of 3.
  • 2 spirals of blood projectiles that rotate clockwise at different speeds.
  • 3 lines of blood projectiles that alternate between slowly curving right and left with every shot fired. The angle these lines of projectiles are fired out at alternates between slightly rotating clockwise and counterclockwise.

• Mega Blast
  Closes his eyes and fires a wide brimstone laser downwards.

• Head Slam
  Slams his head into the floor 1-3 times, creating disorganized bursts of projectiles with each slam

• Rock Wave
  Holds up one hand and slams it down near the player, creating a circular rock wave, which streches out for 3-4 tiles

• Rock Wave+
  Slams the floor 6 times with both of his hands, creating horizontal rock waves, which travel downwards, and decrease in size as they do so.

• Support
  Occasionally spawns mini-bosses/weak bosses to aid Mega Satan in fighting the player. Mega Satan can spawn the following sets of enemies:
  • Gluttony & Envy
  • Sloth & Pride
  • Wrath & Greed
  • Lust
  • The Hollow

  Stagger 1
  After taking 750 damage (85% HP), Mega Satan backs up into the darkness, becoming invincible.
  Shortly after, Famine and Pestilence spawn.
  Killing both spawns War and Death.
  Killing both of them makes Mega Satan vulnerable again.

  Stagger 2
  After taking 1500 damage (70% HP), Mega Satan becomes invulnerable again and spawns Super Envy.
  Killing Super Envy spawns Super Lust and Super Wrath.
  Killing both spawns Super Greed, Super Sloth, Super Pride and Super Gluttony.
  Killing all four makes Mega Satan vulnerable again

  Stagger 3
  After taking 2250 damage (55% HP), Mega Satan becomes invulnerable again and spawns Fallen Uriel, a reskin of Uriel with slightly more HP.
  Killing Fallen Uriel spawns Fallen Gabriel, which just like Fallen Uriel, has slightly more HP than their normal variant.
  Killing Fallen Gabriel makes Mega Satan vulnerable again.

  Phase 2
  Bringing Mega Satan down to 40% HP triggers Phase 2

Attacks & Behavior (Second Phase):

• Behavior
  Mega Satan falls into the darkness, and pops back up as a skull shortly after. Has a completely new set of attacks, which only include complex projectile patterns; Mega Satan loses his hands and also cannot spawn bosses in this phase.

• Projectiles
  Fires projectiles in either of these patterns:
  • 2 spirals of projectiles that slowly rotate counterclockwise. The shots zig-zag as they travel outward.
  • 2 lines of projectiles that alternate between curving left and right. These lines combine to create curving lines with a safe space that moves from the left of the arena to the right.
  • Rings of projectiles, with every other wave fluctuating in speed as it travels.
  • Many lines of projectiles that slowly curve to the left (black) and right (red); these lines create safe spaces to maneuver in that slowly shift to the right.
  • Many lines of projectiles that wiggle as they travel and slowly curve to the left (black) and right (red); these lines create unmoving safe spaces between them.
  • Six lines of projectiles, half of which slowly curve to the left (black) and right (red). These lines create safe spaces that slowly move towards Mega Satan.
  • Rings of projectiles that rotate clockwise (red) and counterclockwise (black) simultaneously.
  • Several lines of projectiles that slowly wiggle as they travel, similarly to the Wiggle Worm trinket. The angle these shots are fired at either rotates clockwise or alternates between rotating clockwise and counterclockwise.
  • Many lines of projectiles that spin as they travel, similarly to the Ring Worm trinket. The angle these shots are fired at constantly randomizes
  • Dense rings of projectiles that wiggle as they travel.
  • Several lines of projectiles that make large zig-zags as they travel.
  • Several lines of projectiles that continuously converge onto each other

• Death
  Upon death, Mega Satan:
  • Kills all projectile entities
  • Immediately cuts the game to Ending 16 after finishing the death animation
  • Has a 50% chance to not end the game, and instead spawns the End Chest alongside a portal to the Void.

Tips for the fight:

• Even with lots of health, this fight can still screw you over. Make sure to have a really good build, otherwise, you’ll have a bad time
• During the second stagger, prioritise Super Pride over the other three minibosses

Final Bosses – Delirium

Appears in: The Void
HP: 10000
Armor: Variable, and only present in boss form. Does not apply for the true form
Phases: 1

Arena & Behavior:

• Arena
  Standard 2×2 arena

• Behavior
  Stationary in true form. Occasionally teleports to a random position in the room. Transforms into bosses the player has previously fought in their run, and uses their attacks against the player, while also performing its own, unique projectile attacks, which are:
  • 20 projectiles that slowly rotate clockwise or counterclockwise slowly while expanding
  • 16 projectiles outwards in all directions
  • 14 projectiles that rotate clockwise, counterclockwise, or back and forth while expanding.
  • 10 Projectiles that fluctuate in and out while expanding.
  • 8 slow-moving green-tinted Ipecac-like projectiles in all directions.
  • 6 projectiles that travel outwards in a zig-zag pattern.
  • 4 projectiles outwards in a lop-sided cross.
  • 4 lines of 3 projectiles that spiral outwards.
  • Spread of 5 projectiles in Isaac’s direction.
  • A burst of projectiles that travel outwards in random directions
  • A stray short-range projectile in a random direction.

  Delirium’s attack and movement speed increases the more damage they take. This is indicated by them turning red.

• Additional Notes
  • Delirium may rarely transform into two bosses
  • Delirium may assume the form of a champion boss, instead of the normal version
  • Delirium will occasionally switch to its true form for a while
  • When switching to a multi-phase boss, the boss will assume the phase based on Delirium’s current HP
  • Delirium regains a very small amount of health when switching to a boss

• Death
  Upon death, Delirium:
  • Spawns the End Chest upon finishing their death animation

Tips for the fight:

• Delirium gains an absurd amount of boss armor over time, turning even the strongest of builds into dog toys. Make sure to come to the fight with a lot of health, because regardless of how good your build is, the fight will take time
• Particularly horrible bosses to encounter prior to fighting Delirium are:
  • Mama Gurdy (the spike attack and the projectile attacks. also possible telefragging)
  • Mega Satan (ability to summon harbingers/deadly sins/angels)
  • Baby Plum (unfathomable speed when decently enraged)
  • Gemini or Steven (Suture does not disappear when Delirium transforms into another boss)
  • The Haunt (brimstone attack)
  • Fistula or Teratoma (very high speed when in small form)
  • Polycephalus, The Stain or The Pile (pops up right on the player)
  • Adversary (homing brimstone)
  • Daddy Long Legs/Triachnid (for being Daddy Long Legs)
• Due to the previous point, it may sometimes be better to try to head straight for Delirium when in the Void instead of fighting the other bosses
• Constantly keep your eyes on Delirium, do not lose sight.
• A good benchmark when wondering if you can beat Delirium is if you can beat Hush without getting damaged. If you were able to do that, you stand a decent chance at defeating Delirium.

Final Bosses – Mother

Appears in: Corpse II
HP: 4222
Armor: 90
Phases: 2

Arena, Attacks & Behavior (First Phase):

• Arena
  1×1 arena, which gets expanded to 1×2 in Phase 2

• Behavior
  Stays at the top of the screen and cycles between five attacks. Mother takes damage to her head and her two hands, which all share the same health bar, unlike in the Mega Satan fight, where damaging Mega Satan’s hands disables them for a while.

• Knife
  Mother takes out a knife from either her left or right side and throws it towards the bottom of the screen. This knife sends out projectile lines perpendicular to it. When the knife hits the wall it spawns a radial burst of projectiles. This attack happens very fast

• Ground Slam
  Mother slams the ground with either her left or right hand, which releases a radial burst of 5 projectile lines and ~3 maggots.

• Maggots
  Mother straightens her hand, which explodes afterwards, releasing ~7 maggot-like projectile lines which home in on the player after a while.

• Horde
  Mother slightly hides off-screen and summons a horde of undead Isaac-like enemies spawning from the bottom of the screen. Any of these enemies which reach Mother get flung by her at the player. The intensity of the spawning increases until Mother slams both of her fists upwards, which causes all of these enemies to die.

• Fistula
  Mother spits out a fistula-like ball which then she starts knocking at the player. The ball additionally spawns a radial burst of projectiles every time it hits a wall up to 1 times. Mother hitting the ball resets this counter, making the ball able to spawn the burst again. After a while, Mother slams the fistula open, splitting it into smaller parts, which split further and then spawn a horde of maggots.

• Phase 2
  Dealing enough damage to Mother triggers Phase 2.

Attacks & Behavior (Second Phase):

• Behavior
  Mother retreats into herself, and fires a massive Brimstone laser downwards shortly after, which expands the arena. Flies out of the corpse, and Phase 2 is initiated. Slowly floats towards the player and performs four attacks

• Spin
  Mother starts spinning, shooting out small wavy lines of projectiles. This attack lasts around 5 seconds.

• Projectile Ball
  Mother starts sucking in debris from the environment. This debris can damage the player. The direction of the sucking changes depending on the player’s position. After a while, Mother spits out a ball of projectiles, which splits into smaller copies of itself after impact. These copies spawn small radial bursts of projectiles.

• Slide
  Mother jumps into the air, and starts sliding across the side of the room Isaac is in. Mother then slides on the opposite side. After the 2 slides are done, she lands back in the middle, spawning rock waves and short-ranged wavy projectile lines.

• Barrage
  Mother spawns a barrage of projectile lines, indicated by the glowing lines which appear ~0.5s before impact. This attack repeats ~6 times.

• Death
  Upon death, Mother:
  • Kills all projectile entities
  • Spawns the End Chest

Tips for the fight:

• High speed and small size really help for this fight. 1.50-2.00 speed is optimal
• Try not to stress and focus on dodging, attacking in between Mother’s attacks.
• Your success is largely dependant on RNG in Phase 1; if you get the Fistula attack, say goodbye to your run.
• For the Maggots attack, it’s best to stay opposite of the exploding hand; this gives you the most reaction time
• For the Horde attack, it’s best to weave right to left in the bottom-middle of the screen, shooting any undead Isaacs that come from under the player
• For the Spin attack, you can actually just weave up-down/left-right or sometimes even stay in place.
• During the Slide attack, Mother always slides from the side farthest from the player

Final Bosses – The Beast – Ultra Horsemen of the Apocalypse

This section is split into two because of the 8’000 section character limit
Appears in: Hell
HP: 10000 (17800 if counting harbingers) (20200 if counting harbingers and Dogma)
Armor: 60
Phases:

• 3, if counting the Beast itself
• 10, if counting the Beast and the Harbingers
• 12, if counting the Beast, Harbingers and Dogma

This fight is triggered when the player defeats Dogma. The screen turns off like an old TV and a cutscene plays. After it ends, or if skipped, the fight begins.

The boss battle begins by fighting the four ultra harbingers; Ultra Famine, Ultra Pestilence, Ultra War and Ultra Death

HP: 2000
Armor: 30
Phases: 2

Attacks & Behavior (First Phase):

• Behavior
  Appears from the right side of the screen and floats in the air. Cycles between two attacks

• Charge
  Ultra Famine charges off screen and comes back from the same side, shooting five lines of five projectiles in a radial half burst and then floats offscreen and does the same attack from the other side. In total, Famine fires the burst 5 times before the attack ends.

• Oscillation
  Ultra Famine floats off screen and comes back from the same side, oscillating up and down while also spawning flies behind him. These flies stay still in the air for 1-2 seconds before starting to float towards the player

• Phase 2
  Depleting enough of Famine’s health triggers the second phase

Attacks & Behavior (Second Phase):

• Behavior
  Ultra Famine’s body and stead explode, leaving the head, which has only one attack.

• Blood Storm
  Ultra Famine floats to the center of the screen and fires 6 simultaneous bursts of tears with alternating orientations. Stray bullets fly out of Famine very often.

• Death
  Depleting all of Famine’s health kills him and makes Ultra Pestilence spawn

HP: 1800
Armor: 30
Phases: 2

Attacks & Behavior (First Phase):

• Behavior
  Appears from the right side of the screen, accompanied by a swarm of flies, and cycles between two attacks

• Toxic Bomb
  Pestilence shoots a projectile in an arc towards the player’s position. Upon contact with lava, this projectile spawns a column of toxic gas and spawns 4 lava projectiles on each side of the explosion which are launched up to about 3/4ths of the screen’s height. In total, Pestilence shoots three of those projectiles. The toxic gas stays up until the end of the maggot attack

• Maggot Attack
  Pestilence launches a maggot from his right eye, which loops around the screen three times before switching sides and doing the same thing before landing back in Pestilence’s eye. The maggot appears from a random height on the screen, making this attack usually pretty devastating.

• Phase 2
  Depleting enough of Pestilence’s health triggers the second phase

Attacks & Behavior (Second Phase)

• Behavior
  Pestilence’s head explodes, leaving the body. Floats in place and has two attacks.

• Ball of Flies
  Pestilence’s stead sometimes coughs out a ball of flies. This ball floats towards the player and spawns flies upon taking damage.

• Tear Rain
  Pestilence’s body sprays out a spread of tears towards the sky, which fall down slowly shortly after.

• Death
  Depleting all of Pestilence’s HP kills him and spawns Ultra War

HP: 2000
Armor: 30
Phases: 2

Attacks & Behavior (First Phase):

• Behavior
  Appears from the right side of the screen and cycles between two attacks

• Giga Bomb
  Ultra War throws a large bomb, which explodes in a cross pattern, and spawns 8 lines of projectiles flying in both cardinal and diagonal directions when it explodes. In total, Ultra War throws three of these bombs before using his next attack.

• Fireballs
  Ultra War flies off screen and wraps around the lava pool, spawning fireballs in an alternating pattern.

• Phase 2
  Depleting enough of War’s health triggers the second phase

Attacks and Behavior (Second Phase):

• Behavior
  Ultra War’s stead explodes and War himself turns black. Floats midair

• Lunge
  Ultra War starts floating towards the player and lunges at them diagonally, shooting fires in all cardinal directions shortly afterwards. In total, Ultra War lunges two times.

• Bounce
  Ultra War pulls out a giga bomb and hugs it. After it explodes, War starts bouncing upwards before plummetting into the lava. When War emerges, 4-6 lava fireballs launch into the sky.

• Death
  Depleting all of War’s health kills him and spawns Ultra Death

HP: 2000
Armor: 30
Phases: 1

Attacks & Behavior:

• Behavior
  Appears from the right side of the screen and cycles between three attacks

• Scythe Swarm
  Spawns 11 scythes opposite to him, which float towards the player’s position. In total, Death uses this attack three times before switching to the next

• Skull Swarm
  Death floats off-screen and comes back from the same side, accompanied by a swarm of skulls. These skulls oscillate up and down. After a while, Death summons three, harmless scythes which kill all of the skulls

• Shadow Attack
  The screen darkens and death disappears into the darkness. Death appears close to the player and swings his scythe at them. In total, Death performs this attack four times.

• Death
  Depleting all of Death’s health kills him and angers The Beast

Final Bosses – The Beast

Defeating all ultra horsemen spawns The Beast.

Attacks & Behavior (First Phase):

• Behavior
  Appears on the right half of the screen and cycles between three attacks

• Charge
  The Beast charges at the player, while harmful stalactites and stalagmites spawn behind them

• Inhale
  The Beast starts inhaling 8 rings of fire, which have one small gap each, through which the player can fly to avoid damage.

• Giga Brimstone
  At the end of Inhale, the Beast fires a massive Brimstone laser, covering most of the screen. The only safe space is all the way on top of the screen.

• Phase 2
  After the Beast reaches 50% health, the second phase triggers. There is no visual indication of Phase 2 triggering

Attacks (Second Phase):

• Attack Lost: Inhale, Giga Brimstone
  The Beast is no longer able to perform Inhale and Giga Brimstone

• Attacks Kept: Charge (buffed)
  The Beast is still able to perform Charge, and now stalactites can also be broken and will fall down when near the player.

• Radial Burst
  The Beast fires a radial burst of fire, and a burst of fast-moving projectiles, piercing the horizontal safe space in between the fire.

• Souls
  The Beast roars and spawns four Souls of the Beast, which float around in a weird pattern before homing onto the player.

• Submerge
  The Beast submerges into the lava and starts firing fireballs from the lava at increasing intensity. Afterwards the Beast emerges, accompanied by a few more fireballs flying out from the lava.

• Phase 3
  When the Beast reaches 33% health, the third phase triggers

Attacks & Behavior (Third Phase):

• Behavior
  The Beast loses all previous attacks and is forced to submerge and reappear on the other side.

• Charge
  The Beast performs the charge attack endlessly. Stalactite/stalagmite spawns are slightly increased and cannot be broken anymore. The Beast takes visual damage the less health it has.

• Death
  Upon death, the Beast:
  • Triggers the final ending cutscene upon finishing its death animation

Tips for the fight:

• As with the ultra horsemen, the faster you kill the Beast, the less damage you’ll take
• As with the ultra horsemen, high speed helps; 1.50-2.00 is optimal, while anything below 1.00 very often results in unavoidable damage
• Famine’s Oscillate attack is extremely hard to dodge, and will almost always result in the player getting hit if they cannot kill the flies fast enough, which usually happens on a decent-good build. Killing the flies is necessary, as Famine will usually charge from the side the player is currently trying to dodge the flies on, which in most cases results in unfair damage.
• Pestilence’s balls of flies can be knocked into the lava with enough fire rate/knockback, which deals considerable damage to them
• War should be taken care of before they have the chance to lunge for the 3rd time in Phase 2, the 3rd lunge can easily catch the player offguard
• Death’s Scythes can actually be killed. This can be used as a last resort if there is no space to dodge them.
• During Inhale, do not stand close to the Beast. The Beast sucks the player in stronger the closer they are to it, and when standing right next to the Beast it’s near impossible to get out.
• During the buffed charge, you can avoid the falling stalactites either by standing very close to the Beast or by standing very far away from it, since these stalactites always fall when they reach the middle of the screen
• Rotten Tomato is a very good item to have on this fight; the horsemen will have their attention diverted from you and will focus on whatever has the status effect and the Beast itself can get hit by its own stalactites and fire rings.
• Dr. Fetus is an automatic defeat on this fight, and if you have piercing along with it you’re even more screwed.
• Practice makes perfect. This fight is one of the fights that can be no-hit with practice without the need of good RNG (including Dogma)

Final Bosses – Ultra Greed

Appears in: Greed Mode, Ultra Greed Floor
HP: 3500
Armor: 85-170, amount depends on HP lost
Phases: 1 (2 in Greedier Mode)

Arena, Attacks & Behavior:

• Arena
  Standard 1×2 arena, with shopkeepers near both of the vertical walls

• Behavior
  Stands still. Performs 5 attacks. Ultra Greed’s projectile/melee attacks cause the player to drop coins. Ultra Greed can pick these coins up and heal himself using them.
  Ultra Greed’s movement and attack speed increases the less health he has

• Charge
  Moves towards the player if they’re cardinal to Ultra Greed

• Spawn Keeper
  Stomps 4 times, with each stomp spawning a Keeper enemy. There is a cap of 4 Keepers alive at once

• Projectiles
  Spits out 3, 4 or 5 coin projectiles towards the player. Rarely can spit out a Monstro-like spray of coins

• Spin
  Spins, firing coin projectiles in random directions

• Lottery
  Ultra Greed stops moving and his eyes start spinning. The outcome of the roll determines the type of coin that’s going to rain down from the ceiling. 4 possible coin types can spawn:
  • Blank Coin – Spawns if Ultra Greed’s eyes do not match. Deals contact damage. HP withers away over time
  • Key Coin – Spawns if Ultra Greed’s eyes are both keys. Sits in place and if not destroyed, turns into a key after some time, which opens one of the arena doors, spawning a large amount of Greed Gapers
  • Heart Coin – Spawns if Ultra Greed’s eyes are both hearts. Sits in place and if not destroyed, heals Ultra Greed for 13 HP
  • Bomb Coin – Spawns if Ultra Greed’s eyes are both bombs. Sits in place and explodes if not destroyed

• Block
  If there are too many entities in the room, Ultra Greed will assume a defensive stance, making him unable to take damage until most of the entities are killed.

• Death/Phase 2
  Upon death, Ultra Greed:
  • Spawns the End Chest along with the Greed Donation Machine
    • Does not apply for Greedier Mode. In Greedier, Ultra Greed will turn into Ultra Greedier upon death, and will continue the fight

Tips for the fight:

• If you maxed out the Greed Donation Machine already, make sure to bring as little coins as possible during the Ultra Greed fight in order to prevent him from regaining health using your coins
• After Lottery, if the Bomb Coins fell down, make sure to check the shopkeepers and pick up any of the coins dropped by them, so Ultra Greed won’t be able to use them to heal himself
• Star of Bethlehem is a guaranteed win
• Prioritise killing the Keeper enemies over damaging Ultra Greed
• The coins spawned during Lottery have large amounts of HP. Trying to kill them is a lost cause

Final Bosses – Ultra Greedier

Appears in: Greedier Mode, Ultra Greed Floor
HP: 2500
Armor: 60

Attacks & Behavior:

• Behavior
  Spawns from Ultra Greed’s death statue. When spawned, all arena doors spew out a brimstone laser. Has a completely new set of attacks

• Projectiles
  Fires a spread of 3, 4 or 5 explosive projectiles towards the player. Rarely fires a Monstro-like spray of explosive projectiles

• Slam
  Slams his fists into the ground, causing the arena doors to spew out brimstone lasers.

• Leap
  Leaps off-screen and tries to land on the player, while also dropping explosive coins. Spawns 4 rock waves upon impact.

• Stomp
  Stomps the ground 4 times, causing Bomb Coins to fall

• Death
  Upon death, Ultra Greedier:
  • Turns the room to gold
  • Spawns the End Chest along with the Greed Donation Machine

Tips for the fight:

• Keep as much distance between you and Ultra Greedier as possible. Constantly stay in a corner, in which Ultra Greedier is not present and wait for him to leap, before moving to another corner.

Achievements – Introduction

TBoI: Rebirth contains 637 secret screens, assuming all DLCs are installed.
All of these achievemetns will be listed down below, sorted by secret screen number

Base game achievements are from:
ID 1 (Magdalene)
to
ID 178 (Lord of the Flies)

Afterbirth achievements are from:
ID 179 (Fart Baby)
to
ID 276 (Mega)

Afterbirth+ achievements are from:
ID 277 (Backasswards)
to
ID 403 (Bound Baby)

Repentance achievements are from:
ID 404 (Bethany)
to
ID 637 (Dead God)

IMPORTANT:

Most achievements will have “[RTN]” in the “Unlocks:” section of the table.

This stands for “refer to name”, and means that the achievement will unlock the thing it is referring to in the name/image.

For example, the achievement Magdalene (ID 1) will unlock the Magdalene character, as evidenced by the achievement name and picture.

Achievements #1

These are achievements from ID 1 to ID 19

Achievements #2

These are achievements from ID 20 to ID 38

Achievements #3

These are achievements from ID 39 to ID 58

Achievements #4

These are achievements from ID 59 to ID 77

Achievements #5

These are achievements from ID 78 to ID 97

Achievements #6

These are achievements from ID 98 to ID 118

Achievements #7

These are achievements from ID 119 to ID 138

Achievements #8

These are achievements from ID 139 to ID 157

Achievements #9

These are achievements from ID 158 to ID 176

Achievements #10

These are achievements from ID 177 to ID 195

Achievements #11

These are achievements from ID 196 to ID 215

Achievements #12

These are achievements from ID 216 to ID 235

Achievements #13

These are achievements from ID 236 to ID 253

Achievements #14

These are achievements from ID 254 to ID 273

Achievements #15

These are achievements from ID 274 to ID 293

Achievements #16

These are achievements from ID 294 to ID 313

Achievements #17

These are achievements from ID 314 to ID 331

Achievements #18

These are achievements from ID 332 to ID 350

Achievements #19

These are achievements from ID 351 to ID 369

Achievements #20

These are achievements from ID 370 to ID 388

Achievements #21

These are achievements from ID 389 to ID 407

Achievements #22

These are achievements from ID 408 to ID 427

Achievements #23

These are achievements from ID 428 to ID 447

Achievements #24

These are achievements from ID 448 to ID 467

Achievements #25

These are achievements from ID 468 to ID 486

Achievements #26

These are achievements from ID 487 to ID 505

Achievements #27

These are achievements from ID 505 to ID 524

Achievements #28

These are achievements from ID 525 to ID 542

Achievements #29

These are achievements from ID 543 to ID 561

Achievements #30

These are achievements from ID 562 to ID 580

Achievements #31

These are achievements from ID 581 to ID 599

Achievements #32

These are achievements from ID 600 to ID 618

Achievements #33

These are achievements from ID 619 to ID 637

Challenges – Introduction

Challenges were in TBoI since its flash version, introduced in the Wrath of the Lamb expansion.
At that time, the game had a measly 10 challenges.
Nowadays, in TBoI: Rebirth, the game contains 45 challenges, assuming all of the DLC is installed.

Challenges are custom runs, with a specific goal in the form of a final boss, and limitations, which can range from treasure rooms not spawning, to being blindfolded, to having your companion explode every few seconds.

Completing challenges rewards you by unlocking certain things.
Achievements cannot be earned when playing a challenge.

All challenges are listed down below, sorted by the order they appear in the menu.

Challenges #1

Challenges #2

Challenges #3

Challenges #4

Completion Marks

Completion marks and the post-it notes hosting them have been added in TBoI: Rebirth. They track the progress of a character that note is assigned to
Each mark represents a final boss

• The heart represents Mom’s Heart/It Lives!
• The cross represents Isaac
• The square with a dot inside of it represents ???
• The penny symbol represents Greed Mode
• The inverted cross represents Satan
• The hollow rectangle represents The Lamb
• The brimstone symbol represents Mega Satan
• The star represents Boss Rush
• The melted face represents Hush
• The knife represents Mother (Corpse II)
• The note represents The Beast
• The tattered note represents Delirium
• If the boss has been defeated on Hardmode, the mark will have a red outline (and the tattered note will be covered in blood)

Secret Seeds – Introduction

Inputting certain seeds in the main menu activates special effects, that affect your run in different ways. There are 72 such seeds.
The seeds will be categorized into their respective sections.
NOTE: Certain seeds disable achievements.

---

1. In the character selection screen, open the seed input box
2. Type in the seed
3. If inputted correctly, a popup will appear, confirming the activation of the effect

The steps are pictured below

Secret Seeds – Curses

These seeds apply curses to the player for the whole duration of the run.

Secret Seeds – Curse Immunities

These seeds grant immunities to certain/all curses

Secret Seeds – Damage Modifiers

These are all the seeds that have something do to with damage to the player

Secret Seeds – Control Modifiers

These seeds affect the player’s controls

Secret Seeds – Camouflage

These seeds camouflage certain parts of the game or make them straight up invisible

Secret Seeds – Player Appearance

These seeds change how the player’s character looks

Secret Seeds – VFX

These seeds change certain visual effects in the game

Secret Seeds – HUD

These seeds affect the HUD

Secret Seeds – Enemy Modifiers

These are the seeds which affect enemies

Secret Seeds – Sound Modifiers

These seeds affect sounds in the game

Secret Seeds – Miscellaneous

These are the seeds which could not be grouped into their separate categories

Debug Console

The Debug Console is a tool which, as the name suggests, can be used to debug the game.

It can be opened using the ~ key, but needs to be enabled beforehand in the options.ini file,
located inside:

Inside options.ini, you need to find the line EnableDebugConsole=0, and switch the value from 0 to 1. Upon restarting the game, the console will be enabled.

Having the Debug Console enabled will disable achievements if the player has not defeated Mom yet on the current savefile. It will also prevent the player from being able to play daily challenges for as long as it is enabled.

The Debug Console has 35 available commands, plus 10 commands that are hidden from the player.
They will be listed down below.

Debug Console Commands #1

Commands are listed in the order they appear in the console

spawn

Spawns an entity in the center of the room based on the given information
The syntax is as follows:

spawn [enemy].[type].[subtype].[champion]

Spawning invalid entities will usually crash the game.
Spawning the Coplayer entity will crash the game, and can rarely corrupt save data

Example: “spawn 10.3.3.1” This will spawn a maggot-spawning Yellow Champion Rotten Gaper

goto

Teleports the player to the floor’s specific room layout based on the given information.
The syntax is as follows:

FOR NORMAL ROOMS: goto d.[room_ID] FOR SPECIAL ROOMS: goto s.[room_type].[room_ID]

The game will also suggest an x tag alongside s and d, but it does nothing,
and attempting to go to a room using the x tag will not work, and will print an error in the console.

Example: “goto s.boss.1010” This will teleport the player to Monstro’s boss room

stage

Teleports the player to a floor based on the given information
The syntax is as follows:

stage [stage_ID]

Appending a letter to the stage number will send the player to the floor’s alternate version

Example: “stage 6d” This will send the player to Gehenna II

gridspawn

Spawns a grid tile in a specified spot in the room based on the given information.
The syntax is as follows:

gridspawn [tile_ID] [grid_ID]

The player can specify the position where the grid tile will be spawned by appending a grid ID (from 0 to 134) number after the tile ID.
Not appending such a number will result in the command placing the tile in a random grid cell in the room.

Example: “gridspawn 1300 53” This will spawn a TNT tile in grid 53

debug 11 can be used to look up the grid IDs

debug

Toggles a debug mode based on the given number (from 1 to 13)
The syntax is as follows:

debug [#]

debug 1 will draw a marker at the position of each entity
debug 2 will show the tile ID of each grid cell. Usually doesn’t work properly
debug 3 will make the player invulnerable to damage.
debug 4 gives the player a flat +40.0 damage
debug 5 displays room info on the bottom of the screen
debug 6 draws red circles on top of entities which represent their hitboxes
debug 7 displays how much damage entities are taking, including the player
debug 8 gives infinite active item charge
debug 9 gives +50.0 luck
debug 10 makes all enemies take extreme amounts of damage many times per second
debug 11 shows the ID and coordinates of grid cells
debug 12 displays a tiny menu showing the player’s currently held items and temporary effects
debug 13 functions like debug 6, but for grid tiles

giveitem

Gives the player an item based on the given information
The syntax is as follows:

“giveitem [item]” Where [item] represents the item’s name, or its tag composed of its type+ID (e.g. c15, which corresponds to the “<3” item)

The command can be shortened to just g, as shown in the examples below

Examples: “giveitem Polyphemus” will give the player the Polyphemus item “giveitem pol” will also give the player Polyphemus “g c169” will also give the player Polyphemus “g pol” will also give the player Polyphemus

Collectibles are prefixed as follows:

“c” stands for ‘collectible’, and will give the player a passive/active item. Example: c700, which corresponds to the Echo Chamber passive item “t” stands for ‘trinket’, and will give the player a trinket. Example: t128, which corresponds to Finger Bone “p” stands for ‘pill’, and will give the player a pill with a specific pill effect. Example: p15, which corresponds to the Tears Down pill effect “k” stands for ‘card’, and will give the player a card with a specific effect. Example: k1, which corresponds to the ‘0 – The Fool’ tarot card. Runes, soul stones, and other non-pill consumables will also use card IDs

remove

Removes items from the player based on the given information
The syntax is as follows:

“remove [item]” The [item] tag functions identically to giveitem’s [item] tag

The command can be shortened to just r, as shown in the examples below.
An asterisk can also be used to remove one instance of every item in the game from the player’s inventory

Examples: “remove polyphemus” will remove a single instance of the Polyphemus item from the player. “r pol” will also remove a single instance of the Polyphemus item from the player. “r c169” will also remove a single instance of the Polyphemus item from the player. “r *” will remove one instance of every item in the game from the player

costumetest

Grants the player 2-6 random costumes. Used for costume compatibility testing.
The player can append a number to specify the amount of random costumes.

Example: “costumetest 3” will give the player 3 random costumes

time

Prints the in-game time in the console

restart

Restarts the run.
A number from 0 to 40 can be appended to specify which character they want to be after the restart.
Inputting an invalid number will crash the game

Example: “restart 1” will restart the run, and set the current character to Magdalene

listcollectibles

Prints in the console a list of collectibles the player has, and how many of each.

repeat

Repeats the last given command.
A number can be appended to specify how many times the command should be repeated.
This number caps at 10’000

Example: “repeat 109” will repeat the last given command 109 times

clearseeds

Removes all easter egg seeds that are currently active in the run

seed

Starts a run with the given seed

Example: “seed GGGG GGGG” will start a run with the GGGG GGGG seed

challenge

Restarts the run and starts a challenge run based on the given challenge ID (1-45)
Inputting challenge 0 will start a normal run, and not a challenge one.

Example: “challenge 45” will start the DELETE THIS challenge

Starting a challenge run with an invalid ID crashes the game

combo

Gives the player a specified amount of items from an item pool based on the given information.
The syntax is as follows:

combo [pool_ID].[item_amount]

The pool ID is auto-suggested by the console, so I will not be putting every pool in here.

Examples: “combo 0.120” will give the player 120 random items from the Treasure Room item pool “combo 12.1” will give the player a random item from the Curse Room item pool

cutscene

Plays a cutscene based on the given ID (1-26)

Example: “cutscene 10” plays the cutscene for unlocking the Experimental Treatment item

clearcache

Unknown effect.

Debug Console Commands #2

macro

Triggers a set of commands based on the given information.
The commands are as follows:

“macro mom” triggers the following commands: • stage 6 • g Bible • g k5 • debug 3 • debug 4 “macro momh” triggers the following commands: • stage 8 • g Bible • g k5 • debug 3 • debug 4 “macro hush” triggers the following commands: • stage 9 • g k5 • combo 0.8 • combo 2.8 • combo 1.3 • combo 4.3 “macro bigchest” triggers the following commands: • stage 10a • g Polaroid • g Negative • debug 3 • debug 4 • g Mutant • g Soy • giveitem Belt • repeat 5 • giveitem Lord of the Pit • debug 10 • g k5 “macro hud” triggers the following commands: • giveitem Dead Cat • repeat 2 • giveitem Guppy’s Collar • giveitem MEAT! • repeat 12 • giveitem Compass • giveitem Blue Map • giveitem Treasure Map • giveitem Baggy • giveitem p2 • giveitem p3 • giveitem Purse • giveitem Paper Clip • giveitem Petrified • giveitem My Little Unicorn “macro fc” triggers the following commands: • debug 3 • debug 8 • debug 9 • giveitem Soy • giveitem Bar • giveitem Pad “macro ms” triggers the ‘goto s.boss.5000’ command, which teleports the player to the Mega Satan fight. “macro mss” triggers the following commands: • goto s.boss.5000 • giveitem Soy • giveitem Mutant • debug 3 • debug 4 “macro ug” triggers the following commands: • stage 11a • goto s.boss.6000 “macro ugg” triggers the following commands: • stage 11a • goto s.boss.6000 • giveitem Sad Onion • giveitem Sad Onion • giveitem Torn • giveitem Torn • giveitem Mutant • giveitem Pentagram • giveitem A Dollar • giveitem Pyro • giveitem debug 3 “macro qk” triggers the following commands: • giveitem Belt • repeat 5 • giveitem Lord of the Pit • giveitem Treasure Map • giveitem Blue Map • giveitem Compass • giveitem Black Candle • giveitem X-Ray • giveitem We Need to Go Deeper • debug 8 • giveitem Dollar • giveitem Pyro • giveitem Skeleton Key • debug 3 • debug 10

playsfx

Plays a sound effect based on the given ID

Example: “playsfx 791” will play the narrator sound effect for using a ??? horse pill

prof

No function

profstop

Used to stop “prof”

curse

Grants a curse (or a set of curses) based on the given number (1-128)

reseed

Generates a new copy of the current floor using a different run seed

eggs

Unlocks all easter egg seeds. Cannot be undone

copy

Copies a specified amount of previously given console commands into the clipboard.

“copy 3” will copy the last three given commands to your clipboard

luarun

Runs a LUA file based on the file path given

luamem

Reports memory usage for LUA

luamod

Runs a mod’s ‘main.lua’ file based on the mod folder name given

reloadshaders

Reloads graphical shaders

lua

Directly runs a line of LUA code.
The command can be shortened to just “l“

clear

Clears the console

metro

Guarantees the next item chosen when using the Metronome active item.
The syntax works the same as giveitem, or remove

delirious

Guarantees the next boss chosen when using the Delirious active item, based on the boss ID given (1-61)

reloadfx

Reloads floor-specific visual effects

Hidden Console Commands

restock

Restocks all shops

giveitem2

Functionally identical to giveitem, but gives the items to a secondary character instead, such as Esau.
The command can be shortened to just “g2“

Example: “g2 c169” will give the Polyphemus item to the secondary character

remove2

Functionally identical to remove, but removes the items of a secondary character instead, such as Esau.
The command can be shortened to just “r2“

Example: “r2 c169” will remove a single instance of the Polyphemus item from the secondary character

forceroom

Gives 1000.0 weight to the specified room, making it very likely to appear once the reseed command is used to regenerate the floor
Has a syntax identical to the goto command.

Example: “forceroom s.boss.1010” will force the boss room of the reseeded floor to be a Monstro fight.

The command does not overwrite final boss rooms, or rooms of a similar nature, as the forced room follows the same generation rules as a normal room.

addplayer

Adds another player entity based on the given information
The syntax is as follows:

addplayer [amount] [character_ID] The [character_ID] parameter works identically to the one used in the restart command

The player entities have the exact same moveset as the player

rewind

Triggers the Glowing Hourglass active item effect

testbosspool

Prints a list of boss names and percentage chance for them to spawn (100%=10000) for current floor.

netstart

Used in setting up online co-op.
by SlayXc2 explains the process quite well

netdelay

Changes network delay to a specific value (e.g. netdelay 1).
Used to remedy connection issues; the value should be set as low as possible if your connection is good and viceversa

reloadwisps

Reloads Book of Virtues wisps and Abyss locusts

Note Dump

This section hosts any notes, tips or pieces of trivia which were not able to be included in the guide for a multitude of reasons.

Guide Trivia #1: Items

• The most complicated item, based on guide description length, is the Blood Puppy item, with its guide description having 925 characters (spaces included). If we count the notes alongside the description, the character count goes up to 1’219. This equates to roughly 15.2% of a section’s max length
• The most common item, based on the amount of item pools it appears in, is the Mom’s Bottle of Pills item, which appears in seven unique item pools.
• The Scat Man challenge starts you off with the most unique items, at 9.

Guide-making trivia #1: The basics

• Steam guides use BBCode, a simpler form of HTML.
  The Steam version of this language is also limited, since you can’t use [style] tags, [color] tags, etc. (The [img] tag is also now [previewicon]), essentially limiting you to the (almost) very basics.

• The hard character limit of a Steam guide section is 8’000 characters, while the hard limit for section titles is 128. This limit can be surpassed by inserting an image, but saving the section will always result in a “FAILURE CODE: 8” until the characters past 8’000 are removed.

Guide-making trivia #2: Section titles and tag parsing

• Section titles can actually parse just as many tags as section bodies, meaning it is very much possible to put a table in the title of a section, although there will be a huge space below the title.
• The property above also applies to images, although insering them into a title is quite finicky, since you need to insert the image into the body first, and then cut and paste that image code into the title. The resulting title looks extremely awkward depending on what image you use, and usually putting images into the title is just a bad idea, especially since clicking the section will usually result in the user being redirected to the page of the image itself.

Guide Trivia #2: Length

• The guide has 334 sections. If we were to assume that each section reaches the 8’000 character limit, the guide would contain roughly 2.6 million characters. In reality, this number is probably somewhere between 1.3 to 2.0 million. If you were to make a handwritten physical copy of this guide, it would take you a little under a month (26 days) if we were to assume the theoretical 2’600’000 character model.
• If we were to include the entire section list, to the right of the guide, in a single image,
  

  View post on imgur.com

  [imgur.com]. The image is 310 by 10349 pixels and weighs 778 KB (.png format).

Gameplay tricks #1: Increasing FOV

• You can increase the area you can see at once in-game by downscaling the window. For this reason, this method only works in windowed mode.
• If you want to have increased FOV and have the game in fullscreen at once, you’ll have to go to the options.ini file and screw around with the MaxRenderScale= parameter.
• Increasing FOV is super useful in Greed Mode, where awareness is a huge part of how your run is going to go.
• Comparison between FOVs:

  • View post on imgur.com

    [imgur.com]

  • View post on imgur.com

    [imgur.com]

Gameplay tricks #2: Relog scumming

• When in combat, and you’re sure that damage is inevitable and will soon occur, you can exit the run and continue it again. This will set you at the beginning of the room, and respawn all enemies in the spots they spawned in, essentially reverting time and preventing the aforementioned “inevitable” damage.
• This does not reset pickup counts, so if you took a hit, you took a hit, and you’re not going back. This also does not recharge items like the Holy Mantle, or revert Holy Card charges. This method also works for pressing buttons in trap rooms.
• Keep in mind that this technique is pretty scummy, and it’s up to you and your moral compass to decide whether you want to use it or not

Miscellaneous note #1: Plan C against Final Bosses

• Out of the 12 final bosses, Plan C can fully kill 7 of them while also giving the player enough time to live for the completion mark to register. The other four final bosses require Plan C to be used in their last phase for the completion mark to be granted, while killing Mother with Plan C will not grant the completion mark regardless of in which phase the item was used.

Final Boss
Killable w/ Plan C?
Mom
Yes.
Obviously does not grant a completion mark, but Mom is considered a final boss anyway.
Mom’s Heart / It Lives
Yes
Satan
Kills only one phase.
Killing the last phase grants the completion mark.
Isaac
Yes
The Lamb
Kills only one phase.
Killing the last phase grants the completion mark.
???
Yes
Hush
Kills only one phase.
Killing the last phase grants the completion mark.
Mega Satan
Kills only one phase.
Killing the last phase grants the completion mark.
Delirium
Yes (with exploit)[1]
Mother
No
The Beast
Yes[2]
Ultra Greed
Yes.
Kills only one phase in Greedier.
Killing the last phase grants the completion mark.
• [1] – Pausing after every burst of static and unpausing when it goes away lets Delirium die faster, granting the completion mark.
  

  View post on imgur.com

  [imgur.com]

• [2] – This is because all of the Ultra Horsemen and the Beast itself are fully loaded when the player enters the arena. Using Plan C kills all of the Horsemen and the Beast at once, granting the completion mark.

» END «

» END «

Special Thanks

I’d like to thank:

• スydonia for helping me with the Items chapter and for creating the guide for original TBoI, inspiring me to do the Rebirth version
• The Official TBoI: Rebirth Wiki[bindingofisaacrebirth.gamepedia.com] for most of the information

Changelog

Here will be listed all changes made to the guide
Big changes will have their date underlined

Time zone: CEST (GMT+1)

14th July 2018, 20:09
Creation of the guide

12th February 2019, 23:49
Guide published

13th February 2019, 16:26
Fixed alphabetical order in Achievements – Characters

13th February 2019, 21:06
Fixed formatting error in Achievements – Challenges #1

17th February 2019, 14:52
Added note about long loading times in the guide description

5th March 2019, 17:04
Added the Milestones section

9th March 2019, 14:47
Fixed grammatical issues in the Debug Console section

16th March 2019, 22:32
Made some small changes to the Custom Content section

18th March 2019, 22:15
Renamed the Fun Facts section to Fun Facts/Trivia
Added a lot more stuff to the Fun Facts/Trivia section

19th March 2019, 15:46
Added the Future Plans section

20th March 2019, 21:39
Fixed a gramatical issue in the Active Treasure Room Items #4 section

28th April 2019, 12:55
Changed “Secrets” in the Index to “Achievements”

3rd May 2019, 19:11
Added the Perhaps check out my other megaguide: section

17th May 2019, 16:38
Remade the Milestones section

17th May 2019. 16:43
Fixed gramatical issue in the Fun Facts/Trivia section

2nd June 2019, 18:07
Fixed the horrible formatting in the Attributes section
Changed the formatting in this section from [b][h1]date[/h1][/b], [b]event[/b] to [b]date[/b], event

6th June 2019 – The Renovations Update pt. 1
(16:32) Renovated Pickups – Hearts
(16:36) Renovated Pickups – Coins
(16:39) Renovated Pickups – Bombs
(16:40) Renovated Pickups – Keys
(16:46) Renovated Pickups – Chests
(16:50) Renovated Consumables – Tarot Cards
(16:55) Renovated Consumables – Playing Cards
(16:57) Renovated Consumables – Special Cards
(17:03) Renovated Consumables – Runes

9th June 2019, 11:43
Fixed grammatical errors in Victory Laps

10th June 2019, 11:21
Updated Debug Console

22nd June 2019 – The Renovations Update pt. 2
(12:04) Updated Characters
(12:06) Updated Characters #2
(12:08) Renovated Rules – Special Rooms #1
(12:10) Renovated Rules – Special Rooms #2
(12:21) Renovated Rules – Floors
(12:27) Updated Modes
(12:30) Renovated Machines
(12:34) Renovated Status Effects
(12:37) Renovated Tear Effects
(12:44) Renovated Mini Bosses – Other
(12:46) Renovated Bosses – Introduction
(13:16) Renovated 11 achievement sections. The rest is awaiting completion
(24th June, 20:40) Renovated 12 achievement sections
(24th June, 20:46) Renovated Custom Challenge Launcher – Challenge Creation
(24th June, 20:50) Completely renovated ▓ END ▓

[UNKNOWN] 2019, [UNKNOWN]
Added Head of Krampus to Other Items (thanks, shosple colupis)
! ░ This entry was added with the Lump of Coal entry because I forgot to add it.

12th August 2019, 12:57
Added Lump of Coal to Other Items (thanks, HairyOreo)

12th August 2019, 13:07
Added the ANNOUNCEMENTS section

12th August 2019, 13:24
Moved the ANNOUNCEMENTS section to the very top of the guide, and deleted Future Plans

8th November 2019
(16:40) Fixed grammatical issues in Index
(16:45) Fixed grammatical issues in Consumables – Introduction
(16:47) Fixed grammatical issues in Consumables – Tarot Cards
(16:49) Fixed grammatical issues in Consumables – Playing Cards
(16:53) Fixed grammatical issues in Consumables – Special Cards
(16:59) Fixed grammatical issues in Characters – Strategies

9th November 2019
(18:29) Fixed grammatical issues in Modes
(18:30) Fixed grammatical issues in Active Shop Items #3
(18:31) Fixed grammatical issues in Bosses – Chapter I #1
(18:32) Fixed grammatical issues in Bosses – Chapter I #2
(18:34) Fixed grammatical issues in Bosses – Chapter II #1
(18:35) Fixed grammatical issues in Bosses – Chapter II #2
(18:36) Fixed grammatical issues in Bosses – Chapter III #1
(18:37) Fixed grammatical issues in Bosses – Chapter IV
(18:38) Fixed grammatical issues in Final Bosses – Hush
(18:39) Fixed grammatical issues in Final Bosses – The Lamb
(18:39) Fixed grammatical issues in Final Bosses – Mega Satan
(18:40) Fixed grammatical issues in Achievements – ???
(18:41) Fixed grammatical issues in Achievements – Other #1
(18:41) Fixed grammatical issues in Challenges – Tips
(18:42) Fixed grammatical issues in Debug Console
(18:43) Fixed grammatical issues in Fun Facts/Trivia

27th December 2019, 21:17
Removed the Perhaps check out my other megaguide: section, due to the other comprehensive guide being severely outdated. As for the comprehensive guide itself, it’s visibility was set to Private until it has been updated with new content.

27th December 2019, 21:45
Removed the Fun Facts/Trivia section.

27th December, 2019 – Section Names Update
(21:55) Added section name image to Controls
(21:57) Added section name image to Index
(21:58) Added section name image to Environment – Introduction
(21:59) Added section name image to Pickups – Introduction
(22:00) Added section name image to Consumables – Introduction
(22:00) Added section name image to Attributes
(22:01) Added section name image to Characters
(22:02) Added section name image to Rules – Floors
(22:02) Added section name image to Victory Laps
(22:03) Added section name image to Modes
(22:03) Added section name image to Machines and Beggars
(22:04) Added section name image to Status Effects
(22:04) Added section name image to Tear Effects
(22:05) Added section name image to Item Pools
(22:05) Added section name image to Items – Introduction
(22:06) Added section name image to Trinkets – Introduction
(22:07) Added section name image to Transformations – Introduction
(22:07) Added section name image to Enemies – Introduction
(22:08) Added section name image to Mini-Bosses – Introduction
(22:09) Added section name image to Bosses – Introduction
(22:10) Added section name image to Final Bosses – Introduction
(22:11) Added section name image to Achievements – Introduction
(22:11) Added section name image to Challenges – Introduction
(22:12) Added section name image to Completion Marks
(22:12) Added section name image to The Breakening
(22:13) Added section name image to Custom Challenge Launcher – Introduction
(22:14) Added section name image to Debug Console
(22:15) Added section name image to Custom Content – Introduction
(22:16) Added section name image to ▓ END ▓
(22:17) Added section name image to Special Thanks
(22:18) Added section name image to Milestones
(22:19) Added section name image to this section

8th March 2020, 17:00
Changed the wording in Custom Content – Antibirth

8th March 2020, 17:05
Added Lost and Forgotten to the Custom Content section

26th April 2020, 16:21
Removed Fun Facts from the Index, and added Milestones

26th April 2020
(16:37) Updated Environment – Introduction
(16:42) Updated Environment – Rocks
(16:42) Updated Environment – Fires
(16:44) Updated Environment – Poops
<TEXT LIMIT>

Changelog #2

(16:45) Updated Environment – Gaps
(16:46) Updated Environment – Creep
(16:48) Updated Environment – Spikes
(16:48) Updated Environment – Turrets
(16:49) Updated Environemnt – Other

20th June 2020, 11:20
Updated Environment – Creep

23rd June 2020
(15:25) Removed Milestones
(15:26) Modified guide description

21st July 2020. 22:25
Removed Milestones from the index

15th September 2020, 19:42 – 20:00
Updated the visuals and added/updated some information to all “Final Bosses” sections.

18th September 2020, 19:52 – 20:00
Updated descriptions for the following items:

• Monstro’s Lung
• Brimstone

25th October 2020, 18:23 – 18:41
Renovated Rules – Floors
Updated Rules – Special Rooms #1 and Rules – Special Rooms #2
Updated Items – Introduction

24th September 2020
(8:16) Fixed a visual issue in Pickups – Chests
(8:18) Fixed a visual issue in Pickups – Hearts
The fixes above are temporary, and will be replaced by a better looking version later today i am a lazy ass mf

27th January 2021
(13:27) Updated Introduction and changed date formatting in Announcements to ISO 8601

31st January 2021
(21:30) Renamed Characters – Strategies to Characters – Tips
(22:15) Updated tips for challenges 1.-12. in Challenges – Tips. More updates tomorrow, if I don’t forget.

1st February 2021
(8:50) Updated tips for challenges 13.-15. in Challenges – Tips. More updates later this afternoon.
(17:59) Split Challenges – Tips into two parts due to section size limit.
(19:59) Improved visual quality of the table in Enemies – Champions
(19:59) Updated tips for challenges 15.-23. in Challenges – Tips. More updates tomorrow

2nd February 2021
(19:03) Updated tips for challenges 24., 25., 26., 28., 29., 31. and 35.

4th February 2021
(13:34) Updated tip for challenge 27.

8th February 2021
(19:42) Updated tips for challenges 33. and 32.

12th February 2021
(11:25) Changed line length in Trinkets #1.
(11:35) Changed line length in Trinkets #2-#8.

17th February 2021
(07:55) Fixed a typo in Trinkets #6

27th March 2021
(17:04) Fixed a typo in Machines & Beggars

31st March 2021
(21:32) Tweaked visuals in Characters #2
(21:35) Added unlock conditions for Bethany and Jacob & Esau in Characters #2
(22:18) Added a note about how to access The Corpse, it’s located in Characters #2 under Jacob & Esau, but it will be moved into its own separate section once mod support comes back.
(22:21) NOTE: The tables for Bethany and JacobEsau will also not be present. Their tables will be moved to Characters #3, and the unlock conditions will be moved to Characters – Unlock conditions once mod support comes back
(22:24) NOTE: Considering adding a section about easter egg seeds, might do that tomorrow

2nd April 2021
(10:38) Updated recharge for Blank Card in Active Treasure Room Items #1
(11:32) Slightly tweaked some things in Characters #2
(12:32) Tweaked visuals in Characters
(12:44) Tweaked visuals in Characters #2
(13:01) Updated Attributes to match Repentance values
(13:08) Updated tables in Characters #1 to match Repentance values
(13:45) FIxed error in Attributes: base range stat changed from 6.00 to 6.50
(13:48) Fixed the same error in Characters and Characters #2
(13:53) Updated tables in Characters #2 to match Repentance values
(14:03) Updated Custom Content – Antibirth
(14:07) Created Secret Seeds and updated Index
(14:48) Finished Secret Seeds – Introduction
(14:51) Created Secret Seeds – Curses
(15:01) Finished Secret Seeds – Curses
(15:01) Created Secret Seeds – Curse Immunities
(15:06) Finished Secret Seeds – Curse Immunities
(15:10) Created Secret Seeds – Damage Modifiers
(15:15) Finished Secret Seeds – Damage Modifiers
(15:15) Created Secret Seeds – Control Modifiers
(15:20) Finished Secret Seeds – Control Modifiers
(15:30) Made all the secret seeds tables even in width
(15:30) Added a note in THE BREAKENING
(15:32) Created Secret Seeds – Camouflage
(15:36) Finished Secret Seeds – Camouflage
(15:37) Created Secret Seeds – Player Appearance
(15:45) Finished Secret Seeds – Player Appearance
(15:51) NOTE: Taking a short break
(16:51) Created Secret Seeds – VFX
(16:54) Finished Secret Seeds – VFX
(16:55) Created Secret Seeds – HUD
(17:00) Finished Secret Seeds – HUD
(17:03) Created Secret Seeds – Enemy Modifiers
(17:07) Finished Secret Seeds – Enemy Modifiers
(17:08) Created Secret Seeds – Sound Modifiers
(17:11) Finished Secret Seeds – Sound Modifiers
(17:12) Created Secret Seeds – Miscellaneous
(17:26) Finished Secret Seeds – Miscellaneous
(17:54) Updated Characters – Tips and also added tips for the Repentance characters
(17:55) Created Characters #3
(18:30) Finished Characters #3
(18:39) Updated hardmode in Modes to match Repentance
(18:48) Created Characters – Unlock Criteria
(19:00) Finished Characters – Unlock Criteria
(19:02) NOTE: Taking a break from updating the guide for today. I’ll come back with more updates tomorrow
(20:05) Updated 20/20 in Passive Treasure Room Items #1

3rd April 2021
(12:02) Created Rules – Repentance Floors
(14:24) Finished Rules – Repentance Floors
(14:30) Created Rules – Repentance Floors – Unlocking the Corpse
(14:34) Updated Characters – Unlock Criteria
(15:37) Finished Rules – Repentance Floors – Unlocking the Corpse
(15:42) Updated Items – Introduction

4th April 2021
(19:35) Removed fake info in Rules – Repentance Floors – Unlocking the Corpse

6th April 2021
(18:33) Updated description for Technology 2

8th April 2021
(13:11) Updated Debug Console, added (outdated) tags
(13:26) Updated Completion Marks to match Repentance
(13:34) Updated Rules – Repentance Floors, created Rules – Repentance Floors – Going Home
(14:36) Finished Rules – Repentance Floors – Going Home
(16:47) Changed text markup in Bosses – Chapter IV
(16:51) Changed text markup in Bosses – Chapter I #1, Bosses – Chapter II #2, Bosses – Chapter III #1, Bosses – Chapter III #2
(17:02) Updated all final boss images to look better.

9th April 2021
(09:48) Updated Controls; added controls for Jacob & Esau

12th April 2021
(14:38) Created Bosses – Home
(16:02) Finished Bosses – Home
(18:06) Added important note in Bosses – Introduction
(18:14) Created Final Bosses – The Beast
(20:10) Renamed Final Bosses – The Beast to Final Bosses – The Beast – Ultra Horsemen of the Apocalypse
(20:11) Finished Final Bosses – The Beast – Ultra Horsemen of the Apocalypse
(20:12) Created Final Bosses – The Beast
(20:46) Finished Final Bosses – The Beast
(20:47) NOTE: Alright, that’s it for today. Coming back for more tomorrow; gonna start working on the boss section redesigns

14th April 2021
(12:06) Tweaked visuals in Bosses – Home
(12:07) NOTE: Came up with an idea on how to take care of the boss renovation
(12:20) Added tips for the Beast fight in Final Bosses – The Beast
(13:30) Created Enemies – Armor
(14:22) Finished Enemies – Armor
(14:42) Updated Bosses – Introduction
(17:50) 19/102 new boss pictures done, taking a break

Changelog #3

15th April 2021
(11:17) Removed THE BREAKENING and Custom Content from the index
(11:18) Finally decided to remove the THE BREAKENING and Custom Content sections from the guide. These sections were not archived; they are lost forever.
(11:34) Created a temporary checklist section
(18:02) ~32/102 new boss pictures done

17th April 2021
(15:15) 42/102 new boss pictures done
(16:08) [repentance checklist] Visual rework of Rules – Curses finished
(16:17) Visual update to Rules – The Map
(??:??) Renamed Rules – Deal Room Spawning to Rules – Deal Rooms
(16:53) Visual update to Rules – Deal Rooms
(19:10) [repentance checklist] Finished Final Bosses – Mother

18th April 2021
(15:51) [repentance checklist] Added all of the new repentance challenges to Challenges #2

19th April 2021
(20:39) ~60/102 new boss pictures done

20th April 2021
(15:14) 73/73 new boss pictures done; i made a miscalculation and counted final + mini bosses towards the total. working on mini-boss pictures now, since final boss pics were done a long time ago
(16:55) 18/18 new mini-boss pictures done, gonna start taking care of the renovation tomorrow if i feel like it
(21:42) Felt like it, finished Bosses – Geminis. More updates coming tomorrow hopefully
(21:48) Added missing champion versions for Gemini and tweaked visuals in Bosses – Geminis

21st April 2021
(11:40) Finished Bosses – Dingles
(11:43) Updated guide categories and description

22nd April 2021
(10:00) Changed title style of the new boss sections and updated Bosses – Introduction to match the new changes
(12:46) Finished Bosses – Duke of Flies (4)
(12:47) NOTE: dingle is missing his champion versions, gonna add them later
(20:00) Added missing champion versions for Dingle

23rd April 2021
(18:30) Finished Bosses – Harbingers (5) #1
(18:43) Finished Bosses – Harbingers (5) #2

24th April 2021
(20:40) Finished Bosses – Fistula (2)
(20:53) 20% of Bosses – Gurglings (5) done, I’ll do the rest tomorrow

25th April 2021
(13:18) Finished Bosses – Gurglings (5) #1
(13:39) Finished Bosses – Gurglings (5) #2
(21:42) Finished Bosses – The Haunt (3)

26th April 2021
(18:44) 50% of Bosses – Larry Jr (4) done, I’ll do the rest tomorrow

27th April 2021
(11:13) Finished Bosses – Larry Jr (4)
(11:29) Updated Rules – Repentance Floors
(11:58) Heavy content update to Rules – Repentance Floors – Unlocking the Corpse
(12:29) Gallery added to Rules – Repentance Floors – Unlocking the Corpse

28th April 2021
(12:13) Finished Bosses – Monstro (3)

29th April 2021
(11:27) Finished Bosses – Pin (4)

30th April 2021
(11:48) Finished Bosses – Widow (2)
(21:09) Finished Bosses – Little Horn (2)
(22:27) Updated tips for The Beast
(22:30) Updated tips for Dogma

1st May 2021
(18:53) Finished Bosses – Rag Man (2)

2nd May 2021
(15:24) Slight content and visual update to Bosses – Introduction
(16:12) Finished Bosses – Baby Plum
(19:04) Finished Bosses – Rainmaker
(19:15) Finished Bosses – Clog
(19:34) Finished Bosses – Colostomia
(19:50) Finished Bosses – Turdlet
(????) Finished Bosses – Chub (4)

3rd May 2021
(19:27) Updated visuals for Index
(19:52) Finished Bosses – Dark One (2)

4th May 2021
(21:08) Finished Bosses – Mega Fatty (3)

5th May 2021
(17:55) Replaced an incorrect tip in Bosses – Turdlet
(21:47) Finished Bosses – Mega Maw (2)

6th May 2021
(19:03) Finished Bosses – Peep (2)

7th May 2021
(20:04) Finished Bosses – Polycephalus (3)

8th May 2021
(17:40) Finished Bosses – Bumbino
(18:17) Finished Bosses – Reap Creep

9th May 2021
(14:01) Finished Bosses – Hornfel
(14:20) Finished Bosses – Great Gideon
(14:36) Finished Bosses – Singe
(15:16) Finished Bosses – Loki (2)
(20:22) Finished Bosses – Mask of Infamy (2)
(20:41) Finished Bosses – The Siren
(20:52) Finished Bosses – Horny Boys
(21:08) Finished Bosses – Blastocyst
(21:33) Finished Bosses – Daddy Long Legs (2)
(21:45) Finished Bosses – Mr. Fred
(22:35) Finished Bosses – Rotgut, Chimera, The Scourge
(22:35) NOTE: Alright, so that’s the bosses done. I’ll move onto the mini-bosses tomorrow
(22:40) Updated Bosses – Dogma (originally Bosses – Home)
(22:42) NOTE: Forgot about the universal bosses. I’ll have to take care of these tomorrow, got no time right now. I genuinely feel sorry for Steam’s servers desperately trying to figure out what the fuck i’m doing

10th May 2021
(09:03) Forgot to mention; Removed the old boss sections permamently from the guide
(21:48) Updated Mini-Bosses – The Deadly Sins to match the visual style of all Boss sections. Also removed super deadly sins from the section; they’ll be hosted in a section of their own

11th May 2021
(10:42) Updated Bosses – Universal to match the visual style of all Boss sections.
(11:15) Finished Mini-Bosses – The Super Deadly Sins
(11:27) Finished Mini-Bosses – Ultra Pride
(11:32) Finished Mini-Bosses – Krampus
(11:47) Finished Mini-Bosses – Uriel & Gabriel
(12:47) Updated Final Bosses – Mom to match the visual style of all Boss sections and added info about the mausoleum/gehenna version of mom

12th May 2021
(12:23) Updated Final Bosses – Mom’s Heart to match the visual style of all Boss sections and added info about the mausoleum/gehenna version of mom’s heart
(13:33) Updated Final Bosses – It Lives to match the visual style of all Boss sections

13th May 2021
(11:27) Updated Final Bosses – Hush to match the visual style of all Boss sections
(11:54) Added a note about stage HP in Mini-Bosses – Introduction
(14:33) Updated Final Bosses – Satan to match the visual style of all Boss sections

14th May 2021
(09:41) Updated Final Bosses – Isaac to match the visual style of all Boss sections
(10:25) Updated Final Bosses – ??? to match the visual style of all Boss sections

15th May 2021
(14:51) Updated Final Bosses – The Lamb to match the visual style of all Boss sections
(22:05) Updated Final Bosses – Mega Satan to match the visual style of all Boss sections
(22:31) Updated Final Bosses – Delirium to match the visual style of all Boss sections
(22:35) Updated Final Bosses – Mother to match the style of all Final Boss sections
(22:38) Updated Final Bosses – The Beast – Ultra Harbingers of the Apocalypse to match the style of all Final Boss sections
(22:41) Updated Final Bosses – The Beast to match the style of all Final Boss sections
(22:46) removed one (1) apostrophe

16th May 2021
(19:44) Updated Final Bosses – Ultra Greed to match the visual style of all Boss sections
(20:34) Updated Final Bosses – Ultra Greedier to match the visual style of all Boss sections
(20:37) NOTE: the bosses have been finally dealt with, now i can focus on other things

17th May 2021
(22:16) Major visual overhaul to Environment – Rocks

18th May 2021
(11:56) Major visual overhaul to Environment – Fires
(12:41) Major visual overhaul to Environment – Poops

19th May 2021
(20:47) Major visual overhaul to Environment – Gaps
(22:00) Major visual overhaul to Environment – Creep

20th May 2021
(16:35) Major visual overhaul to Environment – Spikes
(17:58) Major visual overhaul to Environment – Turrets
(19:32) Major visual overhaul to Environment – Other

Changelog #4

21st May 2021
(11:35) Major visual overhaul to Pickups – Hearts
(12:00) Major visual overhaul to Pickups – Coins
(12:21) Major visual overhaul to Pickups – Bombs
(12:31) Major visual overhaul to Pickups – Keys
(12:45) Major visual overhaul to Pickups – Batteries
(13:37) Major visual overhaul to Pickups – Chests
(14:09) Major visual overhaul to Pickups – Sacks

22nd May 2021
(13:29) Replaced sprite for the Mimic Chest with the correct one in Pickups – Chests
(14:18) Added the M0DE SEVN secret seed to the secret seed table
(15:56) Major visual overhaul to Consumables – Tarot Cards
(18:10) Finished Consumables – Reverse Tarot Cards
(18:13) Finished Consumables – Reverse Tarot Cards Unlock Conditions

23rd May 2021
(17:12) Major visual overhaul to Consumables – Playing Cards

24th May 2021
(21:43) Major visual overhaul to Consumables – Special Cards

25th May 2021
(21:09) Major visual overhaul to Consumables – Runes

26th May 2021
(10:47) Updated Consumables – Pills
(11:29) Finished Consumables – Pill Effects
(11:44) Finished Consumables – Pill Effects/Notes
(12:29) Major visual overhaul to Attributes

27th May 2021
(08:33) Slight update to Characters
(08:43) Slight update to Characters #2
(09:03) Slight update to Characters #3
(09:36) Visual update to Characters – Unlock Criteria
(11:16) Major update to Characters – Tips #1
(11:50) Finished Characters – Tips #2
(12:16) NOTE: gonna do tainted chars either later in the day or tomorrow. gonna have that table in there as a placeholder for now

28th May 2021
(20:09) Finished Tainted Characters
(20:09) NOTE: this is obviously just a part of the whole thing. not adding a section part number to keep it consistent with the non-tainted char section

29th May 2021
(▓▓:▓▓) Finished Tainted Characters #2
(17:47) Finished Tainted Characters #3
(17:57) Fixed info errors and corrected visuals in Characters
(18:01) Corrected visuals in Characters #2
(18:04) Corrected visuals in Characters #3
(18:08) Slight update to Characters – Unlock Criteria

30th May 2021
(17:45) Finished a part of Tainted Characters – Tips #1
(17:54) Finished Tainted Characters – Tips #1
(18:43) Finished Tainted Characters – Tips #2

1st June 2021
(18:27) Updated tips for Delirium
(18:27) NOTE: wow i really did forget to do anything in regard to the guide yesterday. guess that breaks the update streak
(20:23) I’m disbanding the entire ‘RULES’ section into smaller ones. The Index has already been updated accordingly, but the sections themself will be split up tomorrow.

2nd June 2021
(18:30) Converted Rules – Floors into Floors – Introduction
(21:00) Finished Floors – Chapter I
(21:45) Added a gif showcasing the current in Dross. The best size I could manage without turning the gif illegible was ~1.6MB
(21:58) Embedded a little piece of trivia about Dogma in his boss banner in his section. Hovering over the image should display it. Please report any cases of this not working as intended; I really want to know if this works on various, preferrably all clients.
(22:05) Renamed the corpse and home unlock sections to match the new style

3rd June 2021
(17:44) Finished Floors – Chapter II
(22:38) Finished Floors – Chapter III
(22:41) Corrected info about room size in Attributes
(22:54) Added notes about SVFX for Downpour and Dross

4th June 2021
(16:19) Finished Floors – Chapter IV
(17:20) Finished Floors – The Blue Womb
(17:35) Finished Floors – Chapter V
(17:54) Finished Floors – Chapter VI
(19:11) Finished Floors – Chapter VII (Endgame)

5th June 2021
(15:12) Reworded things in Floors – Unlocking the Corpse and generally improved visuals
(15:32) Reworded and tidied up Floors – Going Home
(16:07) Converted Rules – Special Rooms #1 into Special Rooms – Introduction

6th June 2021
(10:21) Updated tips for a few characters in Tainted Characters – Tips #2, mainly Tainted Forgotten
(15:08) FInished(?) Special Rooms #1
(17:43) Finished Special Rooms #1.
(18:41) Finished Special Rooms #2
(19:28) Finished Special Rooms #3
(19:42) Finished Special Rooms #4
(20:50) Updated Deal Rooms, and removed the Rules – prefix
(20:52) Removed Rules – prefix from Curses
(20:55) Updated The Map, and removed the Rules – prefix
(21:03) Converted Modes into Modes – Introduction
(21:20) Finished Modes – Hardmode
(21:54) Finished a part of Modes – Greed(ier). The rest is coming tomorrow

7th June 2021
(19:07) Finished Modes – Greed(ier)

8th June 2021
(18:55) Updated Machines & Beggars with new visuals and repentance content
(18:55) Deleted Tear Effects
(20:00) Finished Entity Effects
(20:44) Deleted Item Pools and instead merged them into Items – Introduction, which also got an update of its own
(20:49) NOTE: alright, now i’ll see if i can rip the item sprites from the game itself. it should be possible. if i succeed and motivate myself enough to keep doing this, the whole, new, renovated, etc., item section will be done by the end of the month, POSSIBLY before the 20th.
(21:35) NOTE: used the unpacker we got with the game, worked as expected. still need to sort items into passives and actives. i will sort them by internal ID now instead of the name though, since the internal files also sort by ID
(21:41) Updated Items – Introduction accordingly
(22:13) NOTE: all items sorted, ill start working on this tomorrow

9th June 2021
(15:53) Added a single “l”
(19:33) Finished Passive Items #1, the most boring part of this guide renovation begins.
(21:06) Finished Passive Items #1 to Passive Items #4
(22:19) Finished Passive Items #5 and Passive Items #6
(22:20) NOTE: if i keep up this pace, ill be done with the items surely before the 20th

10th June 2021
(16:35) Finished Passive Items #7 and Passive Items #8, and also fixed line length in all item sections
(18:17) Finished Passive Items #9 and Passive Items #10
(20:17) Finished Passive Items #11 and Passive Items #12
(21:04) Finished Passive Items #13

11th June 2021
(19:11) Finished Passive Items #14 and Passive Items #15
(20:09) Finished Passive Items #16

12th June 2021
(10:08) Finished Passive Items #17 to Passive Items #19
(11:27) Finished Passive Items #20 to Passive Items #22
(13:29) Finished Passive Items #23 to Passive items #25
(18:30) added lol.png
(20:29) Finished Passive Items #26 to Passive Items #28
(21:26) Finished Passive Items #29 and Passive Items #30

13th June 2021
(12:17) Finished Passive Items #31
(13:08) Finished Passive Items #32
(13:52) Finished Passive Items #33
(16:29) Removed the Controls section
(17:40) Finished Passive Items #34 and Passive Items #35
(17:40) NOTE: all pre-repentance items finished in just 5 days! pretty good. at this pace i should be done with trinkets in 2-3 days, enemies in a week, and achievements in 1-2 weeks (after i finish the item section, that is. either way, all of the above should be finished before the end of July, possibly even the end of June if a miracle happens)
(18:23) Finished Passive Items #36
(19:12) Finished Passive Items #37
(21:32) Finished a part of Passive Items #38, up to Mars

Changelog #5

14th June 2021
(19:00) Finished Passive Items #38
(20:14) Finished Passive Items #39 to Passive Items #40
(22:08) Finished Passive Items #41 to Passive Items #46
(22:31) Finished Active Items #1
(22:31) NOTE: the passive items are OVER. actives should be finished either on June 16th or June 17th
(22:35) Updated Note
(22:39) Updated Introduction

15th June 2021
(17:00) Finished Active Items #2
(20:32) Finished Active Items #3 to Active Items #6

16th June 2021
(16:36) NOTE: taking a break from active items to focus on things left behind earlier
(19:47) Finally added buckets to Environment – Rocks
(19:55) Finally added gas and the spikeball to Environment – Other
(20:50) Finished Consumables – Soul Stones
(21:05) Finished Characters – Birthright
(21:12) Added Broken Hearts to Pickups – Hearts
(21:19) Added a note about familiars, orbitals, blue flies and blue spiders in Items – Introduction
(21:20) NOTE: “aCtIvEs ShOuLd Be FiNiShEd EiThEr On JuNe 16Th oR jUnE 17tH” my ass
(21:55) Finished Active Items #7

17th June 2021
(13:57) Corrected fake info in Machines & Beggars regarding Crane Games spawning only passive/actives, and not a mix of both
(17:31) Finished Active Items #8
(18:40) Finished Active Items #9
(19:54) Finished Active Items #10

18th June 2021
(18:47) Finished Active Items #11 to Active Items #17
(18:48) NOTE: well, my prediction was somewhat right. gonna start taking care of trinkets soon
(19:10) Finished Special Items #1 and Special Items #2
(21:58) Updated Trinkets – Introduction
(22:37) Finished Trinkets #1
(22:38) NOTE: the table structure allows for 17 tables per section on average, meaning i should be done by the time i reach the 11th or 12th page

19th June 2021
(14:26) Finished Trinkets #2 to Trinkets #4
(18:27) Finished Trinkets #5 to Trinkets #11
(20:28) Finished Trinkets #12 and Trinkets #13
(20:28) NOTE: glad i was somewhat right again about my predicitons. time to take on transformations
(21:18) Updated Transformations – Introduction
(22:35) Finished Transformations #1 and Transformations #2

20th June 2021
(11:21) Updated Enemies – Introduction
(11:32) Renamed and updated Enemies – Armor to Enemies – Entity Armor, Stage HP, and Boss Enemies
(18:38) Finished Enemies – Flies #1 to Enemies – Flies #3
(21:29) Finished Enemies – Spiders #1, Enemies – Spiders #2, and Enemies – Wall Creeps
(21:30) NOTE: Most of the time between 11:32 and 18:38 was spent on downloading enemy pictures, categorizing them, and sorting them. Creating the actual sections is very fast, and I’m expecting to be done with all enemies tomorrow, which is a pretty optimistic forecast, but I’m confident.

21st June 2021
(21:00) Finished Enemies – Poops, Enemies – Worms, Enemies – Maggots, and Enemies – Hoppers
(21:00) NOTE: I’ll be done with all of this either tomorrow of the day after tomorrow

22nd June 2021
(19:17) Finished Enemies – Pacers, Enemies – Maws, Enemies – Gapers, Enemies – Fatties
(23:00) Finished Enemies – Skinnies

23rd June 2021
(13:50) Finished mulligans, clotties, gyros and globins
(13:51) NOTE: im gonna stop writing the full section names because it just takes too long
(15:16) Finished knights, hosts, vises, boils, shopkeepers, gurgles, moles, buttlickers, bats and ghosts
(16:14) Finished bonies and death’s heads
(17:40) Finished whippers, goats, cultists, mom’s hands, masks + hearts, balls, oobs, brains, and guts
(19:52) Finished the rest of the enemies, moving onto achievements

24th June 2021
(13:55) Updated Achievements – Introduction and finished Achievements #1
(14:41) Finished Achievements #2 to Achievements #5
(??:??) Finished Achievements #6 to Achievements #14

25th June 2021
(15:05) Finished Achievements #15
(16:16) Finished Achievements #16
(17:51) Fixed all typos (except for one in the changelog) regarding the word “permament”, which has been corrected to “permanent”
Also removed the Custom Challenge Launcher section from the guide and the index
(21:46) Finished achievements up to #23

26th June 2021
(16:18) Finished all achievements
(18:00) Finished challenges #1 and #2, i’ll do #3 and #4 later
(21:30) Finished the rest of the challenges

27th June 2021
(13:47) Updated Debug Console
(16:40) Finished all console commands
(16:46) Updated » END «
(16:52) NOTE: alright so.. uhh. um.. guess that’s the whole renovation thingy done. didn’t think i’d get to this point. i guess i’ll start adding stuff from my to-do list then, hold on..
(16:54) Updated Bosses – Clog
(17:18) Finished Environment – Shopkeepers
(17:33) Added red rooms to Special Rooms #4

28th June 2021
(11:33) Finished Boss Rush
(11:37) Updated Bosses – Rainmaker
(14:10) Finished Note Dump. I’ll add more if I find something noteworthy
(14:10) NOTE: The “to-do” list is done, which means that this concludes the full renovation. It’s been an interesting journey that has now come to an end. I can finally get some ♥♥♥♥♥♥♥ rest now.

4th July 2021
(19:14) Added Miscellaneous note #1 to the note dump