How to defeat any boss rush on any BC

Mutations you NEED unlocked:
- Tainted flask
- Demon strength
- Cursed flask

Helpful mutations:
- Emergency triage

When entering the boss rush, go red tree, take any weapon as it doesnt really matter cause youll be doing so much damage.

If you feel like it, use assist mode for the 20% boss health.

When selecting mutation grab Tainted flask, Cursed flask, and Emergency triage (for efficiency, not necessary), and just drink as many flasks as you want. You can theoretically get infinite damage however i 1k-2k curse stacks is sufficient.

After you get a bunch of curse reset your mutations and grab Tainted flask, and Cursed power, you can also take Cursed flask again to keep scaling your damage even further during the boss rush.

Finally you can enter the door, and make sure to pop a flask before fighting for the damage buff from tainted flask.

Weapons:

Cursed sword is by far the best, base cursed sword can get over 100k dps, with a few curse stacks you can just 1 tap bosses.

Serpents fang is very good, very fast and the DOT works well with this build as it ignores the immortality bubble.

Giant killer, i'm not even sure you can get this weapon in boss rush as i haven't seen it in buss rush but if you can it would be good for obvious reasons.

Rapier, high dps and you need to be rolling/parrying regardless to not die.

Assassins knife, staying behind bosses to avoid attacks for free crits is nice.

Panchaku, if you take this take Combo instead of cursed flask after stacking curse.

Hemorrhage, good at attacking from a distance to avoid attacks n stuff.

Fire blast, same as hemorrhage although you have to stand stuff to get good damage.

Shields:

Force shield, by far the best, immortality is good when you cant get hit, no brainer if you can get it from the random 3 item selection.

Front line shield, much easier to come across than the force shield, amazing damage output.

Assault shield, good mobility, particularly good for mama tick and conjunc.

Bloodthirsty shield, high dps and the DOT is amazing.

Abilities:

Flamethrower turret, amazing dps, fire DOT is goated, paired with oil is just top tier

Cleaver, solid for concierge, HOTK, the queen, scarecrow, and the 3 lighthouse ♥♥♥♥♥♥♥.

Powerful grenade, is powerful.