Useful Tips & Tricks for Beginners

Resident Evil 54 · 92 ratings4.9k views99 favorites6 min readby Wesker's LadyUpdated Jul 5, 2025View on Steam ↗

🔴 Reload Tricks

● There are two types of reload in Resident Evil 5: Inventory reload and melee reload

- Inventory Reload: Just drag the appropriate ammo to the weapon you want to reload
- Melee Reload: Press the reload key (R by default) before performing a melee attack

Note: You can also reload your weapons and organize your inventory when doing actions, like climbing ladders / fences or picking up objects. Use those tricks to your advantage!

Note #2: This can save you a lot of money, especially the RELOAD upgrades
Note #3: Melee Reload doesn't works with enemies lying on the ground

-------------------------- Inventory reload & melee reload examples -----------------------------

🔴 Normal Draw & Quick Draw

● There are two ways to change weapons in Resident Evil 5: Normal Draw & Quick Draw

- Normal Draw: Just press the desired key (1,2,3) for change to the weapon you want
- Quick Draw: While aiming with a weapon, press the desired key (1,2,3) + attack key

Note: Quick Draw has its advantages, skiping the aiming animation and shooting directly
Note #2: This can be especially useful when using rocket launchers (slow animation)
Note #3: If you are a controller player, use the arrows (◁ ▷ △ ▽ ) for change weapons

● How to organize your inventory depending if you are using Keyboard & Mouse or Controller:

● Video examples:

------------------------------ Normal Draw & Quick Draw examples ------------------------------

🔴 Invincibility trick

● You obtain "invincibility frames" when picking up objects (like ammo / money) or jumping over fences. This is useful when you have a lot of enemies surrounding you or can't aim in time

Note: Don't pick up everything when fighting a lot of enemies. This trick can save you
Note #2: This trick can be useful on higher difficulties, especially Professional

------------------------------ pick up & fence invincibility examples ------------------------------

🔴 How to dodge enemies correctly

● Dodge enemies is the key for not receive damage on higher difficulties

- Correct way: Wait for the enemy to attack. Then, get through to one of his sides
- Wrong way: Go through to one of his sides directly (enemy attacks has "auto-aim")

Note: Be careful with the Majinis that carry long melee weapons (ex: pipes). Kill them quickly

Note #2: Ndipaya Majinis can be difficult to dodge due their spears (their basic attacks has long range). These enemies require you to adopt a more agressive game style rather than dodge

Note #3: Enemies can also throw their melee weapons at you. You can either move right / left or shoot them. You can do the same with molotovs and dynamites (can be useful for groups)

-------------------------------------- Correct & Wrong examples ---------------------------------

🔴 Killing parasites easily (Mutated Majinis)

● The most useful way to kill parasites in Resident Evil 5 is by using Flash Grenades or Rounds

Note: As soon you get the Grenade Launcher, it will be more rentable to kill parasites: You can carry more Rounds than Grenades per slot (Flash Rounds = 12, Flash Grenades 5) + you can use "Quick Draw" trick with it. Also, you can buy Flash Rounds for a cheap price (Flash Grenades not)

Note #2: The parasites emerges when landing a critical hit or the enemy has low HP. You can get more information about it in the "Avoiding Mutations / Clean Kills" section

● Here a list of the different mutation types / parasites:

- Adjule: a parasite with tentacles and teeths
- Bui Kichwa: a spider-type parasite
- Kipepeo: a flying-type parasite
- Duvalia: a shell-like parasite
- Cephalo: A "worm" looking parasite

🔴 Avoiding Mutations / Clean Kills

● The best ways to avoid mutations in Resident Evil 5 are: Neck Breaker and Throat Slit moves. These moves are a insta-kill. Remember that it only works on regular Majinis!

- Neck Breaker: Performed by Chris only
- Throat Slit: Performed by Sheva only

Note: Some enemies in the campaign has an scripted mutation. Meaning, that Majini will always mutate when receiving a critical hit or being low HP. Take notice about which enemies has scripted mutations and not and use that to your advantage!

Note #2: The dogs can mutate into Adjules at will / randomly

------------------------------- Neck Breaker & Throat Slit examples ------------------------------

🔴 Best way to save your partner in PRO difficulty (Coop Only)

● There are two ways to save your partner from "dying status": with healing and resuscitate.
Professional difficulty is one of the most demanding and hard difficulties of the game!

- With healing: Takes time to take out the spray or herbs. Health bar doesn't stop going down
- With resuscitate: Instantly saves your partner from dying and health bar stops going down

🤔 Curious fact: When playing SOLO and using a healing item for save your partner, the health bar stops going down. By the other hand, in COOP, the health bar goes down while healing

Note: The only healing you need to keep in a PRO run are the red herbs
Note #2: Protect your partner until you find a green herb and mix it with the red one
Note #3: If your partner receive another hit after you resuscitate it, is a game over

● With healing and without healing (resuscitate) examples:

🔴 Save with Flash Grenade

This only works in Amateur, Normal and Veteran difficulty. Very useful when your partner is far away from you + surrounded. You can also use the Grenade Launcher with Flash Rounds. That way the enemies will be stunned and won't be able to attack your partner until you arrive.

❗ Note:
by the mid-late game, there will be some enemies inmune to flash grenades, such as the Ndipaya and the military Majinis. They wear some kind of masks made of wood / metal. The wood masks can be broken but not the metalic ones.



🔴 Difference between Bulletproof & Melee Vest in PRO difficulty

● These vests protect you really well on NORMAL and VETERAN difficulty. But on PRO, this is another story. Here I will show you the huge difference between them:

Note: Keep in mind that equipping them will take you one inventory slot each. By not using them, you can have one / two free slots in your inventory. It is up to you to sacrifice some defense for more ammo / weapons. Once you get used to the game, you won't need them

- Melee vest overview (based on Professional difficulty):

- Bulletproof vest overview (based on Professional difficulty):

🔴 Other minor tips that can be useful

- You can knock down the Majinis easily by shooting their legs when they are charging at you
- Hand Grenades / Mines can be also useful against Duvalias and Cephalos (insta-kill)
- Some enemies can't climb. Use that to your advantage and kill them from a safe spot
- Reapers (big bugs) are weak against Electric and Flash Rounds (using the Grenade Launcher)
- All bosses are weak against Rocket Launcher (some need a especific moment to use it right)
- Flash Rounds are effective against wood shields and dynamite / molotov Majinis
- Chris Safari & Warrior costumes can be useful against enemy flash grenades (late game)

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