Beating Uroboros Mkono ( Chapter 5-2 ) with just flame items you get in the chapter finale

According to MiniPlay(CZ), the more FPS you get, the less flame damage you will actually do, based on the distance, this is basically says if the flame grenades travel to a certain distance it will not do flame damage on this boss, although the effect of the flame damage is still there. The flame damage is the effect you need to trigger the weakspot. Because of this, we need to lock the FPS to 60FPS ( recommended ) or 30FPS ( full effect but very bad gameplay so not recommended ).

FIRST METHOD: In-game Framerate
Refresh rate will not affect the game as your focus is on frame rate, locking this seems to work but the in-game lock does have inconsistency.
SECOND METHOD: NVIDIA CONTROL PANEL
This method is more favorable in my opinion, if you have NVIDIA use this
THIRD METHOD: OBS
This third method only works for mid-GPU like GTX 1060 / GTX 1650Ti. If you start recording with encoder on H.264 or QuickSync, the game will most likely drop to 60FPS for smooth rendering while recording. This is a good method to reduce the FPS toward the desired 60FPS

The host MUST be the one to lock their game on 60FPS, this will affect the gameplay condition of the client side aswell ( client doesn't need to stay on 60FPS ). If the host doesn't lock then the client is unable to trigger the weakspot despite locking 60FPS ( i have tested 4 times during random ONLINE session ), same condition applies to the host if they don't lock FPS their game.

As mentioned in the post, you will most likely start with just these items:
Flame Rounds: 5
Flame Grenade: 1 or 2 ( if you picked up 1 grenade when you pick up the SIG MG and kept it till the finale )
I'd recommend you to bring a magnum, prefer an upgraded DAMAGE magnum so you can get the best damage, else like me in this guide to reserve magnum for Wesker fight in Chapter 5-3, i'll use a M3 shotgun that does 900 damage on max upgrade or you can use Hydra SG. For AI, give them your best damage sniper rifle as they will shoot most accurate with. Having pistols are always a great option, especially the SIG P226 ( most damage pistol ) or the M93R ( triple burst DPS ) if your weapons are ran out of ammo

The AI will not likely to attack and keeps following you without shooting if they are on COVER mode, make sure the AI start off with ATTACK mode, that way AI will switch to whatever weapon deals the most damage, in my case a SF75 that does 2000 damage on fully upgraded Damage.
Note It's best sometimes if you start to run around and getting loots, make sure to switch her on COVER to avoid losing crucial sniper / high damage weapon ammo and to avoid her stand still and shooting the boss and start following you. After you loot switch her back to ATTACK if you find a suitable spot for her to shoot.

Not just the flame rounds or grenade that can trigger the weakspots, the explosive containers are also a good way to trigger, here are the locations of them and make sure Mkono consumed these containers then shoot it to trigger the weakspot

Boss Fight video of mine:
TACTICS
The fight will most likely follow this pattern: Weakspot appear -> shoot the 3 weakspots till it's gone -> Fight ends. Simple right? well here are the notes that most player will commonly and mistakenly do:

1. Make sure the boss is not on idle animation, if you shoot too early with the flame rounds or flame grenades. Mkono will scream in agony BUT not trigger the weakspots for you to shoot, STOP shooting and wait till Mkono teleports and reappear THEN start to shoot between it's leg with Flame Rounds or Flame Grenades once WHEN IT STARTS TO MOVE toward you as this is when it's vulnerable animation is triggered.

2. When weakspots appear, keep shooting the weakspot on close range with your shotguns or magnum. AI will automatically shoot these weakspots when it appears. If your CO-OP partner arrives with a sniper, prefer to shoot it at a suitable distance. If you have the sniper same principle although your CO-OP partner needs to have close range to finish the fight and conserve flame items.
3. IF you ran out of flame items mentioned, RESTART CHECKPOINT and try again OR purchase FLAME ROUNDS IN STORE AND TRY AGAIN. Don't bother with the flamethrower, it's the longest and most time consuming method so don't bother, faster to restart !

4. ALL OF YOUR WEAPONS WILL NOT DO DAMAGE TO THIS BOSS ( proven by GE Ultimate Trainer ), YOU CAN ONLY DO DAMAGE TO THE WEAKSPOT, DESTROY 3 OF THEM TO END THE FIGHT!
   

Here are the locations for the ammo / flame grenades you can also get during the fight
Note

• White X: Sniper Ammo
  
• Red X: Flame Grenades ( Total of 3 )
  
• Green X: Shotgun Ammo

In conclusion, the fight is not that hard, it's just poor design from Capcom. I wish they ported the Nintendo Switch port to PC version so we don't have to endure the pain of fighting this spagetti monster.

If you like what i do, you can check my Twitch channel right here. I usually do Resident Evil 5/6 content and many more ( link: https://www.twitch.tv/ladychromatrescu )! Thank you guys for reading this guide post and hopefully you have a great day!

This guide is made by LadyChromatrescu, please do not re-upload this as your own!